How far is Gretna, FL from Port Saint Lucie, FL?
The driving distance from Gretna, FL to Port Saint Lucie, FL is about 403 miles (648.5 km), with a travel time of about 05h 59m by car.
- The straight-line flight distance is about 347.2 miles (558.8 km).
- For a round trip, plan for roughly 11h 59m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 59m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Marion County, Florida, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Rain Showers Likely
Mostly Cloudy then Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Gretna and Port Saint Lucie.
Turn-by-Turn Driving Directions
Step-by-step road directions between Gretna and Port Saint Lucie.
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1
Start on 2nd Street
99 m · 26 sec · 2nd Street
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2
Turn right onto Church Street
802 ft · 30 sec · Church Street
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3
Turn left onto Main Street
1.5 km · 2 min · Main Street
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4
Continue on Blue Star Highway
3.1 mi · 4 min · Blue Star Highway
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5
Continue on West Jefferson Street
1.2 mi · 2 min · West Jefferson Street
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6
Turn right onto South Pat Thomas Parkway
3.5 mi · 6 min · South Pat Thomas Parkway
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7
Take the ramp left toward I 10 East: Tallahassee
2044 ft · 50 sec
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8
Merge slight left
114.6 mi · 2 hr 3 min
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9
Take the exit slight right toward I-75 South: Tampa
1959 ft · 37 sec
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10
Merge slight left
107.2 mi · 1 hr 55 min
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11
Take the exit slight left toward Florida's Turnpike South, Orlando
165.2 mi · 2 hr 57 min · Florida's Turnpike
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12
Take the exit slight right toward Port Saint Lucie
1 mi · 3 min
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13
Continue on Southwest Bayshore Boulevard
147 m · 15 sec · Southwest Bayshore Boulevard
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14
Turn right onto Southwest Port Saint Lucie Boulevard
1.4 km · 2 min · Southwest Port Saint Lucie Boulevard
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15
Turn left onto Southeast Airoso Boulevard
1.6 mi · 3 min · Southeast Airoso Boulevard
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16
Turn left onto Southwest Carter Avenue
66 m · 9 sec · Southwest Carter Avenue
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17
Arrive at your destination
0 m · 1 sec · Southwest Carter Avenue
Car Route Details
A richer read on the saved driving route between Gretna and Port Saint Lucie.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Florida's Turnpike
Take the exit slight left toward Florida's Turnpike South, Orlando
165 mi · 02h 57m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Rain Showers Likely leaving Gretna and Mostly Cloudy then Chance Showers And Thunderstorms near Port Saint Lucie.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Gretna to Port Saint Lucie?
The road trip is about 403 miles (648.5 km) and usually takes 05h 59m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Reddick is a useful midpoint, sitting about 200.3 miles from Gretna and 202.7 miles from Port Saint Lucie.
How much longer is the road route than the straight-line distance?
The direct path is about 347.2 miles (558.8 km), while the road route adds roughly 55.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 5:00 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $58.98 one way or $117.97 round trip. Estimated CO2 is about 126.4 kg one way.
What should you check before leaving?
Before you leave, expect Rain Showers Likely around Gretna and Mostly Cloudy then Chance Showers And Thunderstorms near Port Saint Lucie.
Stop Ideas Near Reddick
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Reddick.
Ocala, Florida
Gainesville, Florida
Waldo, Florida
The Villages-Lady Lake, FL
Flight Path Map
This map shows the direct air route between Gretna and Port Saint Lucie. Straight-line distance: 347.22 mi (558.79 km).
#1 Gretna
Human settlement in Gadsden County, Florida, United States of America
| Population | 1,430 |
| Coordinates | 30.6171400, -84.6599100 |
| Altitude | 90 |
| Country | United States |
#2 Port Saint Lucie
The second most populous city in St.
| Population | 209,715 |
| Coordinates | 27.2939300, -80.3503300 |
| Altitude | 5 |
| Country | United States |
End: Southwest Carter Avenue (-80.350328, 27.294381)
Estimated Travel Time
Distance: 648 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 13h 25m |
| 40 mph (64.37 km/h) | 10h 04m |
| 50 mph (80.47 km/h) | 08h 03m |
| 60 mph (96.56 km/h) | 06h 42m |
| 70 mph (112.65 km/h) | 05h 45m |
| 80 mph (129 km/h) | 05h 01m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $58.98 | $117.97 |
| Mid-grade | $4.60 | $65.36 | $130.71 |
| Premium | $4.90 | $69.62 | $139.24 |
| Diesel | $4.35 | $61.86 | $123.71 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · May 13, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.