How far is Picayune, MS from Southaven, MS?
The driving distance from Picayune, MS to Southaven, MS is about 346.4 miles (557.4 km), with a travel time of about 05h 26m by car.
- The straight-line flight distance is about 309 miles (497.3 km).
- For a round trip, plan for roughly 10h 52m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 26m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Madison County, Mississippi, USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Rain Showers then Mostly Cloudy
Chance Rain Showers then Mostly Sunny
Driving Route Map
The map below follows the saved road route between Picayune and Southaven.
Turn-by-Turn Driving Directions
Step-by-step road directions between Picayune and Southaven.
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1
Start on East Canal Street
638 ft · 22 sec · East Canal Street
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2
Turn right
1.5 mi · 2 min
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3
Turn right onto Highway 43 North
1.1 mi · 2 min · Highway 43 North
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4
Continue on East Sycamore Road
1165 ft · 20 sec · East Sycamore Road
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5
Take the ramp left
1296 ft · 34 sec
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6
Merge slight left
61 mi · 1 hr 5 min
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7
Take the exit slight right toward US 49 North, MS 42 West: Jackson
1123 ft · 39 sec
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8
Continue straight
1.2 mi · 2 min
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9
Continue straight
5.4 mi · 7 min
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10
Continue straight
5.3 mi · 6 min
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11
Continue straight
1077 ft · 14 sec
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12
Continue straight
4.2 mi · 5 min
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13
Continue straight
65.7 mi · 1 hr 20 min
-
14
Take the exit slight right
862 ft · 21 sec
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15
Keep slight left to continue on Jackson
1.1 km · 1 min
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16
Keep slight right
1.5 km · 1 min
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17
Merge slight left
195.7 mi · 3 hr 32 min
-
18
Take the exit slight right toward Southaven, Horn Lake
1717 ft · 44 sec
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19
Turn left onto Stateline Road West
1871 ft · 54 sec · Stateline Road West
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20
Turn left onto Millbranch Road
1285 ft · 37 sec · Millbranch Road
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21
Turn right onto Haleville Drive
1096 ft · 54 sec · Haleville Drive
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22
Turn left onto Five Oaks Drive North
653 ft · 29 sec · Five Oaks Drive North
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23
Arrive at your destination
0 m · 1 sec · Five Oaks Drive West
Car Route Details
A richer read on the saved driving route between Picayune and Southaven.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Jackson
Merge slight left
196 mi · 03h 32m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Rain Showers then Mostly Cloudy leaving Picayune and Chance Rain Showers then Mostly Sunny near Southaven.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Picayune to Southaven?
The road trip is about 346.4 miles (557.4 km) and usually takes 05h 26m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Canton is a useful midpoint, sitting about 172.8 miles from Picayune and 173.5 miles from Southaven.
How much longer is the road route than the straight-line distance?
The direct path is about 309 miles (497.3 km), while the road route adds roughly 37.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 6:08 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $46.28 one way or $92.55 round trip. Estimated CO2 is about 108.6 kg one way.
What should you check before leaving?
Before you leave, expect Chance Rain Showers then Mostly Cloudy around Picayune and Chance Rain Showers then Mostly Sunny near Southaven.
Stop Ideas Near Canton
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Canton.
Union Station
Yazoo City
Vicksburg, MS
Hazlehurst station
Flight Path Map
This map shows the direct air route between Picayune and Southaven. Straight-line distance: 309 mi (497.29 km).
#1 Picayune
City in Pearl River County, Mississippi, United States
| Population | 10,886 |
| Coordinates | 30.5255600, -89.6778800 |
| Altitude | 22 |
| Country | United States |
#2 Southaven
The most populous city in DeSoto County, Mississippi.
| Population | 56,644 |
| Coordinates | 34.9889800, -90.0125900 |
| Altitude | 95 |
| Country | United States |
End: Five Oaks Drive West (-90.012414, 34.988979)
Estimated Travel Time
Distance: 557 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 32m |
| 40 mph (64.37 km/h) | 08h 39m |
| 50 mph (80.47 km/h) | 06h 55m |
| 60 mph (96.56 km/h) | 05h 46m |
| 70 mph (112.65 km/h) | 04h 56m |
| 80 mph (129 km/h) | 04h 19m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $46.28 | $92.55 |
| Mid-grade | $4.26 | $52.04 | $104.09 |
| Premium | $4.63 | $56.52 | $113.04 |
| Diesel | $5.42 | $66.17 | $132.34 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.