How far is Southaven, MS from Picayune, MS?
The driving distance from Southaven, MS to Picayune, MS is about 344.3 miles (554.1 km), with a travel time of about 06h 28m by car.
- The straight-line flight distance is about 309 miles (497.3 km).
- For a round trip, plan for roughly 12h 56m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 28m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Madison County, Mississippi, USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Rain Showers then Mostly Sunny
Chance Rain Showers then Mostly Cloudy
Driving Route Map
The map below follows the saved road route between Southaven and Picayune.
Turn-by-Turn Driving Directions
Step-by-step road directions between Southaven and Picayune.
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1
Start on Five Oaks Drive West
653 ft · 31 sec · Five Oaks Drive West
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2
Turn right onto Haleville Drive
1097 ft · 54 sec · Haleville Drive
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3
At the end of the road, turn left onto Millbranch Road
1307 ft · 39 sec · Millbranch Road
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4
Turn right onto Stateline Road West
1360 ft · 29 sec · Stateline Road West
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5
Take the ramp slight right
2426 ft · 59 sec
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6
Merge slight left
195.5 mi · 3 hr 31 min
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7
Take the exit slight right toward I 20 East, US 49 South: Meridian, Hattiesburg
1.5 km · 1 min
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8
Keep slight right to continue on Richland, Hattiesburg
1.2 km · 2 min
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9
Merge slight left onto Highway 49 South
80.3 mi · 1 hr 37 min · Highway 49 South
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10
Continue straight
2294 ft · 36 sec
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11
Continue straight
1.1 mi · 2 min
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12
Take the exit slight right toward I 59 South: New Orleans, Gulf Coast
1914 ft · 36 sec
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13
Merge slight left onto Lance Corporal Roy M Wheat Memorial Highway
60.7 mi · 1 hr 5 min · Lance Corporal Roy M Wheat Memorial Highway
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14
Take the exit slight right toward MS 43: North Picayune
1355 ft · 33 sec
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15
Turn right onto Highway 43 North
1 mi · 2 min · Highway 43 North
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16
Turn straight
151 m · 22 sec
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17
Turn left
1.5 mi · 2 min
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18
Turn left onto East Canal Street
638 ft · 18 sec · East Canal Street
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19
Arrive at your destination
0 m · 1 sec · East Canal Street
Car Route Details
A richer read on the saved driving route between Southaven and Picayune.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Stateline Road West
Merge slight left
195 mi · 03h 31m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Chance Rain Showers then Mostly Sunny leaving Southaven and Chance Rain Showers then Mostly Cloudy near Picayune.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Southaven to Picayune?
The road trip is about 344.3 miles (554.1 km) and usually takes 06h 28m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Canton is a useful midpoint, sitting about 172.5 miles from Southaven and 171.9 miles from Picayune.
How much longer is the road route than the straight-line distance?
The direct path is about 309 miles (497.3 km), while the road route adds roughly 35.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $46.01 one way or $92.02 round trip. Estimated CO2 is about 108 kg one way.
What should you check before leaving?
Before you leave, expect Chance Rain Showers then Mostly Sunny around Southaven and Chance Rain Showers then Mostly Cloudy near Picayune.
Stop Ideas Near Canton
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Canton.
Union Station
Yazoo City
Vicksburg, MS
Hazlehurst station
Flight Path Map
This map shows the direct air route between Southaven and Picayune. Straight-line distance: 309 mi (497.29 km).
#1 Southaven
The most populous city in DeSoto County, Mississippi.
| Population | 56,644 |
| Coordinates | 34.9889800, -90.0125900 |
| Altitude | 95 |
| Country | United States |
#2 Picayune
City in Pearl River County, Mississippi, United States
| Population | 10,886 |
| Coordinates | 30.5255600, -89.6778800 |
| Altitude | 22 |
| Country | United States |
End: Picayune (-89.67788, 30.52556)
Estimated Travel Time
Distance: 554 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 28m |
| 40 mph (64.37 km/h) | 08h 36m |
| 50 mph (80.47 km/h) | 06h 53m |
| 60 mph (96.56 km/h) | 05h 44m |
| 70 mph (112.65 km/h) | 04h 55m |
| 80 mph (129 km/h) | 04h 17m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $46.01 | $92.02 |
| Mid-grade | $4.26 | $51.75 | $103.49 |
| Premium | $4.63 | $56.19 | $112.39 |
| Diesel | $5.42 | $65.79 | $131.58 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.