How far is Odessa, MO from Saint Charles, MO?
The driving distance from Odessa, MO to Saint Charles, MO is about 195.4 miles (314.5 km), with a travel time of about 02h 56m by car.
- The straight-line flight distance is about 187.3 miles (301.5 km).
- For a round trip, plan for roughly 05h 53m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 56m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
The most populous city in the state of Missouri.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Cloudy
Driving Route Map
The map below follows the saved road route between Odessa and Saint Charles.
Turn-by-Turn Driving Directions
Step-by-step road directions between Odessa and Saint Charles.
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1
Start on West Mason Street
9 m · 5 sec · West Mason Street
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2
Turn right onto South 2nd Street
2611 ft · 2 min · South 2nd Street
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3
At the end of the road, turn right onto West Old U.S. 40
3266 ft · 1 min · West Old U.S. 40
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4
Take the ramp straight toward I 70 East, US 40 East: Columbia
1094 ft · 27 sec
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5
Merge slight left onto Dwight D. Eisenhower Highway
31 mi · 33 min · Dwight D. Eisenhower Highway
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6
Continue on U.S. Submarine Veterans' Memorial Highway
32 mi · 34 min · U.S. Submarine Veterans' Memorial Highway
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7
Keep slight left to continue on U.S. Submarine Veterans' Memorial Highway
22.4 mi · 24 min · U.S. Submarine Veterans' Memorial Highway
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8
Continue on Dwight D. Eisenhower Highway
1.8 mi · 2 min · Dwight D. Eisenhower Highway
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9
Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway
1.6 mi · 2 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
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10
Continue on Sheriff Roger I. Wilson Memorial Highway
1.9 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
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11
Continue on Dwight D. Eisenhower Highway
99 mi · 1 hr 57 min · Dwight D. Eisenhower Highway
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12
Take the exit slight right toward I 70 Business, MO 94: First Capitol Drive, Lewis and Clark Trail
653 ft · 14 sec
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13
Keep slight left to continue on I 70 Business, MO 94 East: First Capitol Drive, Lindenwood University, SSM Health Saint Joseph Hospital
596 ft · 15 sec
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14
Turn straight onto First Capitol Drive
1.5 km · 2 min · First Capitol Drive
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15
Turn slight right onto MO 94
1.4 km · 2 min
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16
Turn left onto South Second Street
1551 ft · 57 sec · South Second Street
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17
Arrive at your destination
0 m · 1 sec · North Second Street
Car Route Details
A richer read on the saved driving route between Odessa and Saint Charles.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Dwight D. Eisenhower Highway
Continue on Dwight D. Eisenhower Highway
99 mi · 01h 57m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Mostly Clear leaving Odessa and Mostly Cloudy near Saint Charles.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Odessa to Saint Charles?
The road trip is about 195.4 miles (314.5 km) and usually takes 02h 56m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Columbia is a useful midpoint, sitting about 96.4 miles from Odessa and 98.9 miles from Saint Charles.
How much longer is the road route than the straight-line distance?
The direct path is about 187.3 miles (301.5 km), while the road route adds roughly 8.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 12:36 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $25.98 one way or $51.96 round trip. Estimated CO2 is about 61.2 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Clear around Odessa and Mostly Cloudy near Saint Charles.
Stop Ideas Near Columbia
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Columbia.
Jefferson City
Sedalia
Hermann
Flight Path Map
This map shows the direct air route between Odessa and Saint Charles. Straight-line distance: 187.31 mi (301.45 km).
#1 Odessa
City in Missouri
| Population | 5,295 |
| Coordinates | 38.9991700, -93.9535600 |
| Altitude | 285 |
| Country | United States |
#2 Saint Charles
A city in St.
| Population | 71,761 |
| Coordinates | 38.7839400, -90.4812300 |
| Altitude | 147 |
| Country | United States |
End: North Second Street (-90.481269, 38.783952)
Estimated Travel Time
Distance: 314 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 30m |
| 40 mph (64.37 km/h) | 04h 53m |
| 50 mph (80.47 km/h) | 03h 54m |
| 60 mph (96.56 km/h) | 03h 15m |
| 70 mph (112.65 km/h) | 02h 47m |
| 80 mph (129 km/h) | 02h 26m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $25.98 | $51.96 |
| Mid-grade | $4.25 | $29.30 | $58.61 |
| Premium | $4.65 | $32.07 | $64.13 |
| Diesel | $5.30 | $36.54 | $73.09 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 29, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.