How far is Muscle Shoals, AL from Opelika, AL?
The driving distance from Muscle Shoals, AL to Opelika, AL is about 225.2 miles (362.5 km), with a travel time of about 03h 52m by car.
- The straight-line flight distance is about 195.9 miles (315.2 km).
- For a round trip, plan for roughly 07h 44m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 52m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
The most populous city in Alabama.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny then Slight Chance Showers And Thunderstorms
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Muscle Shoals and Opelika.
Turn-by-Turn Driving Directions
Step-by-step road directions between Muscle Shoals and Opelika.
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1
Start on Avalon Avenue
15 m · 9 sec · Avalon Avenue
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2
Turn left onto Woodward Avenue
1.3 mi · 2 min · Woodward Avenue
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3
Continue straight
1 mi · 2 min
-
4
Turn left onto Wheeler Highway
4.3 mi · 6 min · Wheeler Highway
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5
Keep slight right to continue on University of North Alabama Highway
55.1 mi · 1 hr 6 min · University of North Alabama Highway
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6
Take the exit slight right toward I-65 South: Birmingham
1557 ft · 38 sec
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7
Merge slight left onto Heroes Highway
43.8 mi · 47 min · Heroes Highway
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8
Take the exit slight right toward I 22 West, US 31: Memphis, Fultondale
2715 ft · 38 sec
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9
Keep slight left to continue on I 22 West: Memphis
2666 ft · 38 sec
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10
Keep slight left to continue on Montgomery
1940 ft · 28 sec
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11
Merge slight left
3.9 mi · 5 min
-
12
Take the exit slight left toward I 20 East, I 59 North: Atlanta, Gadsden
1037 ft · 25 sec
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13
Merge slight right
1 mi · 2 min
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14
Take the exit slight right toward US 31, US 280: Carraway Boulevard, Downtown
1261 ft · 31 sec
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15
Keep slight left to continue on US 31 South, US 280 East
2557 ft · 1 min
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16
Merge slight left onto Red Mountain Expressway
2.5 mi · 3 min · Red Mountain Expressway
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17
Take the exit slight right toward US 280 East: Sylacauga, Zoo Gardens
17.7 mi · 25 min
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18
Take the exit straight
89.5 mi · 1 hr 49 min
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19
Turn left onto Pepperell Parkway
1.5 km · 2 min · Pepperell Parkway
-
20
Continue on 2nd Avenue
1.4 km · 2 min · 2nd Avenue
-
21
Turn right onto North 10th Street
1793 ft · 50 sec · North 10th Street
-
22
Turn left onto Avenue B
142 m · 23 sec · Avenue B
-
23
Turn right onto South 9th Street
25 m · 4 sec · South 9th Street
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24
Arrive at your destination
0 m · 1 sec · South 9th Street
Car Route Details
A richer read on the saved driving route between Muscle Shoals and Opelika.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
US 280 East
Take the exit straight
89.5 mi · 01h 49m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Partly Sunny then Slight Chance Showers And Thunderstorms leaving Muscle Shoals and Mostly Sunny near Opelika.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Muscle Shoals to Opelika?
The road trip is about 225.2 miles (362.5 km) and usually takes 03h 52m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Birmingham is a useful midpoint, sitting about 112.5 miles from Muscle Shoals and 112.8 miles from Opelika.
How much longer is the road route than the straight-line distance?
The direct path is about 195.9 miles (315.2 km), while the road route adds roughly 29.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 9:16 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $30.11 one way or $60.21 round trip. Estimated CO2 is about 70.7 kg one way.
What should you check before leaving?
Before you leave, expect Partly Sunny then Slight Chance Showers And Thunderstorms around Muscle Shoals and Mostly Sunny near Opelika.
Stop Ideas Near Birmingham
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Birmingham.
Birmingham
Brent, AL
Tuscaloosa
Anniston
Flight Path Map
This map shows the direct air route between Muscle Shoals and Opelika. Straight-line distance: 195.84 mi (315.18 km).
#1 Muscle Shoals
City in Alabama, USA
| Population | 14,877 |
| Coordinates | 34.7448100, -87.6675300 |
| Altitude | 152 |
| Country | United States |
#2 Opelika
City in Alabama
| Population | 31,135 |
| Coordinates | 32.6454100, -85.3782800 |
| Altitude | 246 |
| Country | United States |
End: South 9th Street (-85.378252, 32.645431)
Estimated Travel Time
Distance: 363 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 07h 30m |
| 40 mph (64.37 km/h) | 05h 37m |
| 50 mph (80.47 km/h) | 04h 30m |
| 60 mph (96.56 km/h) | 03h 45m |
| 70 mph (112.65 km/h) | 03h 13m |
| 80 mph (129 km/h) | 02h 48m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $30.11 | $60.21 |
| Mid-grade | $4.26 | $33.86 | $67.72 |
| Premium | $4.63 | $36.77 | $73.54 |
| Diesel | $5.42 | $43.05 | $86.10 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Alabama · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.