How far is Mount Pleasant, SC from Thomasville, NC?
The driving distance from Mount Pleasant, SC to Thomasville, NC is about 279.6 miles (449.9 km), with a travel time of about 05h 22m by car.
- The straight-line flight distance is about 213.8 miles (344 km).
- For a round trip, plan for roughly 10h 45m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 22m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in South Carolina, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Sunny
Driving Route Map
The map below follows the saved road route between Mount Pleasant and Thomasville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Mount Pleasant and Thomasville.
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1
Start on the route
23 m · 10 sec
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2
Turn right onto Coleman Boulevard
72 m · 10 sec · Coleman Boulevard
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3
Turn left onto Chuck Dawley Boulevard
1.3 mi · 2 min · Chuck Dawley Boulevard
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4
Turn straight onto Mark Clark Expressway
12 mi · 15 min · Mark Clark Expressway
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5
Take the exit slight right toward US 52 West, US 78 West: Rivers Avenue
1271 ft · 31 sec
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6
Turn slight right onto Rivers Avenue
1.1 mi · 2 min · Rivers Avenue
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7
Turn straight
534 ft · 21 sec
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8
Take the ramp slight right toward I 26 North: Columbia
2641 ft · 45 sec
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9
Merge slight left
99.2 mi · 1 hr 48 min
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10
Take the exit slight right toward US 1 North: West Columbia
1062 ft · 26 sec
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11
Merge slight left onto Augusta Road
2930 ft · 42 sec · Augusta Road
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12
Turn straight onto Jarvis Klapman Boulevard
2.7 mi · 3 min · Jarvis Klapman Boulevard
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13
Continue on Hampton Street
1.4 mi · 3 min · Hampton Street
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14
Turn left onto Bull Street
1.3 mi · 2 min · Bull Street
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15
Continue on I. DeQuincey Newman Freeway
7.6 mi · 9 min · I. DeQuincey Newman Freeway
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16
Merge slight left onto Charles F Bolden Freeway
71.9 mi · 1 hr 20 min · Charles F Bolden Freeway
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17
Continue on General Paul R Younts Expressway
5.9 mi · 8 min · General Paul R Younts Expressway
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18
Continue on Bill Lee Freeway
2.9 mi · 4 min · Bill Lee Freeway
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19
Continue on I-77 North
1.6 km · 1 min · I-77 North
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20
Continue on Bill Lee Freeway
886 ft · 14 sec · Bill Lee Freeway
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21
Continue on I-77 North
1.5 mi · 2 min · I-77 North
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22
Keep slight right to continue on I-77 North
1.3 mi · 2 min · I-77 North
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23
Take the exit slight right toward I 85 North: Greensboro
2095 ft · 51 sec
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24
Keep slight left to continue on I 85 North: Greensboro
971 ft · 24 sec
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25
Continue straight
1047 ft · 26 sec
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26
Merge slight left onto Julius Chambers Highway
48.1 mi · 55 min · Julius Chambers Highway
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27
Keep slight left to continue on I 85 North: Greensboro, High Point
14.7 mi · 16 min
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28
Take the exit slight right toward Lake Road
895 ft · 24 sec
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29
Turn right onto Lake Road
1248 ft · 36 sec · Lake Road
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30
Continue on Baptist Childrens Home Road
1.6 mi · 2 min · Baptist Childrens Home Road
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31
Turn right
805 ft · 44 sec
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32
Turn straight onto West Main Street
1.5 km · 2 min · West Main Street
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33
Arrive at your destination
0 m · 1 sec · West Main Street
Car Route Details
A richer read on the saved driving route between Mount Pleasant and Thomasville.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 26 North
Merge slight left
99.2 mi · 01h 48m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Mount Pleasant and Sunny near Thomasville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Mount Pleasant to Thomasville?
The road trip is about 279.6 miles (449.9 km) and usually takes 05h 22m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Blythewood is a useful midpoint, sitting about 139.9 miles from Mount Pleasant and 139.7 miles from Thomasville.
How much longer is the road route than the straight-line distance?
The direct path is about 213.8 miles (344 km), while the road route adds roughly 65.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 6:14 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $38.80 one way or $77.60 round trip. Estimated CO2 is about 87.6 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Mount Pleasant and Sunny near Thomasville.
Stop Ideas Near Blythewood
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Blythewood.
Columbia
Camden
Denmark
Florence
Flight Path Map
This map shows the direct air route between Mount Pleasant and Thomasville. Straight-line distance: 213.76 mi (344.02 km).
#1 Mount Pleasant
The second most populous city in Charleston County, South Carolina.
| Population | 92,799 |
| Coordinates | 32.7940700, -79.8625900 |
| Altitude | 3 |
| Country | United States |
#2 Thomasville
City in and the county seat of Thomas County, Georgia, United States
| Population | 26,713 |
| Coordinates | 35.8826400, -80.0819900 |
| Altitude | 259 |
| Country | United States |
End: Thomasville (-80.08199, 35.88264)
Estimated Travel Time
Distance: 450 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 18m |
| 40 mph (64.37 km/h) | 06h 59m |
| 50 mph (80.47 km/h) | 05h 35m |
| 60 mph (96.56 km/h) | 04h 39m |
| 70 mph (112.65 km/h) | 03h 59m |
| 80 mph (129 km/h) | 03h 29m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.94 | $38.80 | $77.60 |
| Mid-grade | $4.40 | $43.38 | $86.77 |
| Premium | $4.80 | $47.36 | $94.72 |
| Diesel | $5.84 | $57.56 | $115.13 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in South Carolina · Oct 15, 2026