How far is Thomasville, NC from Mount Pleasant, SC?
The driving distance from Thomasville, NC to Mount Pleasant, SC is about 280.9 miles (452.1 km), with a travel time of about 05h 22m by car.
- The straight-line flight distance is about 213.8 miles (344 km).
- For a round trip, plan for roughly 10h 45m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 22m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in South Carolina, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Thomasville and Mount Pleasant.
Turn-by-Turn Driving Directions
Step-by-step road directions between Thomasville and Mount Pleasant.
-
1
Start on West Main Street
1.1 mi · 3 min · West Main Street
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2
Turn right onto Baptist Childrens Home Road
1.6 mi · 2 min · Baptist Childrens Home Road
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3
Continue on Lake Road
108 m · 11 sec · Lake Road
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4
Take the ramp right
1339 ft · 33 sec
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5
Merge slight left onto Richard Childress Freeway
62.6 mi · 1 hr 9 min · Richard Childress Freeway
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6
Take the exit slight right toward I 77, US 21: Statesville, Columbia
2079 ft · 51 sec
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7
Keep slight left to continue on I 77 South, US 21 South: Columbia
914 ft · 22 sec
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8
Keep slight right
1463 ft · 36 sec
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9
Merge slight right onto I-77 South
4.2 mi · 6 min · I-77 South
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10
Continue on Bill Lee Freeway
2.9 mi · 4 min · Bill Lee Freeway
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11
Continue on General Paul R Younts Expressway
6 mi · 8 min · General Paul R Younts Expressway
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12
Continue on B. Bayles Mack Highway
47.7 mi · 54 min · B. Bayles Mack Highway
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13
Continue straight
24.5 mi · 26 min
-
14
Keep slight left to continue on Charles F Bolden Freeway
3.3 mi · 4 min · Charles F Bolden Freeway
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15
Continue on William Earle Berne Beltway
12.3 mi · 14 min · William Earle Berne Beltway
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16
Continue on Veterans Memorial Freeway
2.8 mi · 3 min · Veterans Memorial Freeway
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17
Keep slight left to continue on I 26 East: Charleston
1.3 km · 2 min
-
18
Merge slight right
94.6 mi · 1 hr 43 min
-
19
Take the exit slight right toward Aviation Avenue, Remount Road
1137 ft · 28 sec
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20
Keep slight left to continue on Remount Road, Hanahan
1865 ft · 46 sec
-
21
Keep slight right to continue on Remount Road, Hanahan
952 ft · 29 sec
-
22
Turn left onto Remount Road
1932 ft · 45 sec · Remount Road
-
23
Turn right onto Rivers Avenue
1.3 km · 1 min · Rivers Avenue
-
24
Take the ramp slight left
1890 ft · 48 sec
-
25
Merge slight left onto Mark Clark Expressway
11.9 mi · 15 min · Mark Clark Expressway
-
26
Continue on Chuck Dawley Boulevard
1.3 mi · 2 min · Chuck Dawley Boulevard
-
27
Turn right onto Coleman Boulevard
72 m · 13 sec · Coleman Boulevard
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28
Turn left
23 m · 6 sec
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29
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Thomasville and Mount Pleasant.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 26 East
Merge slight right
94.6 mi · 01h 43m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Thomasville and Sunny near Mount Pleasant.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Thomasville to Mount Pleasant?
The road trip is about 280.9 miles (452.1 km) and usually takes 05h 22m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Blythewood is a useful midpoint, sitting about 140.5 miles from Thomasville and 140.4 miles from Mount Pleasant.
How much longer is the road route than the straight-line distance?
The direct path is about 213.8 miles (344 km), while the road route adds roughly 67.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 6:14 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $37.20 one way or $74.40 round trip. Estimated CO2 is about 88.1 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Thomasville and Sunny near Mount Pleasant.
Stop Ideas Near Blythewood
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Blythewood.
Columbia
Camden
Denmark
Florence
Flight Path Map
This map shows the direct air route between Thomasville and Mount Pleasant. Straight-line distance: 213.76 mi (344.02 km).
#1 Thomasville
City in and the county seat of Thomas County, Georgia, United States
| Population | 26,713 |
| Coordinates | 35.8826400, -80.0819900 |
| Altitude | 259 |
| Country | United States |
#2 Mount Pleasant
The second most populous city in Charleston County, South Carolina.
| Population | 92,799 |
| Coordinates | 32.7940700, -79.8625900 |
| Altitude | 3 |
| Country | United States |
End: Mount Pleasant (-79.86259, 32.79407)
Estimated Travel Time
Distance: 452 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 21m |
| 40 mph (64.37 km/h) | 07h 01m |
| 50 mph (80.47 km/h) | 05h 37m |
| 60 mph (96.56 km/h) | 04h 40m |
| 70 mph (112.65 km/h) | 04h 00m |
| 80 mph (129 km/h) | 03h 30m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.75 | $37.20 | $74.40 |
| Mid-grade | $4.23 | $41.92 | $83.84 |
| Premium | $4.63 | $45.83 | $91.67 |
| Diesel | $5.72 | $56.68 | $113.35 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in North Carolina · Oct 15, 2026