How far is Memphis, MO from O'Fallon, MO?
The driving distance from Memphis, MO to O'Fallon, MO is about 172.1 miles (277 km), with a travel time of about 02h 53m by car.
- The straight-line flight distance is about 138.1 miles (222.3 km).
- For a round trip, plan for roughly 05h 47m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 53m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Missouri, USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Patchy Frost then Sunny
Sunny
Driving Route Map
The map below follows the saved road route between Memphis and O'Fallon.
Turn-by-Turn Driving Directions
Step-by-step road directions between Memphis and O'Fallon.
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1
Start on West Monroe Street
530 ft · 13 sec · West Monroe Street
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2
Turn right onto South Market Street
2417 ft · 49 sec · South Market Street
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3
Turn left onto Grand Avenue
33.7 mi · 50 min · Grand Avenue
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4
Take the ramp right toward MO 27 South: Hannibal
1519 ft · 42 sec
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5
Merge slight left onto Avenue of the Saints
46.3 mi · 54 min · Avenue of the Saints
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6
Continue on Avenue of the Saints
3.9 mi · 5 min · Avenue of the Saints
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7
Turn right
1.7 mi · 2 min
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8
Turn right onto Veterans Road
3.2 mi · 6 min · Veterans Road
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9
At the end of the road, turn left onto County Road 422
85 m · 7 sec · County Road 422
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10
Continue on Paris Gravel Road
2539 ft · 1 min · Paris Gravel Road
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11
Take the ramp right
37 m · 3 sec
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12
Merge slight left onto Avenue of the Saints
73.7 mi · 1 hr 27 min · Avenue of the Saints
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13
Take the exit slight left toward I 70 East: Saint Louis
2705 ft · 51 sec
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14
Merge slight left onto Dwight D Eisenhower Highway
6.4 mi · 8 min · Dwight D Eisenhower Highway
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15
Take the exit slight right toward MO K: O'Fallon
1765 ft · 43 sec
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16
Turn straight onto Drennen Parkway
46 m · 3 sec · Drennen Parkway
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17
Keep slight right to continue on Drennen Parkway
51 m · 6 sec · Drennen Parkway
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18
Turn slight left onto MO K: O'Fallon
19 m · 3 sec
-
19
Continue on South Main Street
3115 ft · 2 min · South Main Street
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20
Turn right
8 m · 2 sec
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21
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Memphis and O'Fallon.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Avenue of the Saints
Merge slight left onto Avenue of the Saints
73.7 mi · 01h 27m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Patchy Frost then Sunny leaving Memphis and Sunny near O'Fallon.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Memphis to O'Fallon?
The road trip is about 172.1 miles (277 km) and usually takes 02h 53m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Hannibal is a useful midpoint, sitting about 85.9 miles from Memphis and 86.2 miles from O'Fallon.
How much longer is the road route than the straight-line distance?
The direct path is about 138.1 miles (222.3 km), while the road route adds roughly 34 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 12:42 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $22.89 one way or $45.78 round trip. Estimated CO2 is about 53.9 kg one way.
What should you check before leaving?
Before you leave, expect Patchy Frost then Sunny around Memphis and Sunny near O'Fallon.
Stop Ideas Near Hannibal
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Hannibal.
Quincy
Fort Madison station
Macomb
La Plata
Flight Path Map
This map shows the direct air route between Memphis and O'Fallon. Straight-line distance: 138.14 mi (222.31 km).
#1 Memphis
City in Scotland County, Missouri, United States
| Population | 1,815 |
| Coordinates | 40.4578100, -92.1712900 |
| Altitude | 244 |
| Country | United States |
#2 O'Fallon
The most populous city in St.
| Population | 89,769 |
| Coordinates | 38.8106100, -90.6998500 |
| Altitude | 165 |
| Country | United States |
End: (-90.699849, 38.810674)
Estimated Travel Time
Distance: 277 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 44m |
| 40 mph (64.37 km/h) | 04h 18m |
| 50 mph (80.47 km/h) | 03h 26m |
| 60 mph (96.56 km/h) | 02h 52m |
| 70 mph (112.65 km/h) | 02h 27m |
| 80 mph (129 km/h) | 02h 08m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $22.89 | $45.78 |
| Mid-grade | $4.25 | $25.82 | $51.63 |
| Premium | $4.65 | $28.25 | $56.50 |
| Diesel | $5.30 | $32.20 | $64.39 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 02, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.