How far is O'Fallon, MO from Memphis, MO?
The driving distance from O'Fallon, MO to Memphis, MO is about 171.9 miles (276.6 km), with a travel time of about 03h 38m by car.
- The straight-line flight distance is about 138.1 miles (222.3 km).
- For a round trip, plan for roughly 07h 17m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 38m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Missouri, USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Patchy Frost then Sunny
Driving Route Map
The map below follows the saved road route between O'Fallon and Memphis.
Turn-by-Turn Driving Directions
Step-by-step road directions between O'Fallon and Memphis.
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1
Start on the route
8 m · 7 sec
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2
Turn left onto South Main Street
3116 ft · 2 min · South Main Street
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3
Turn left onto I 70 East
10 m · 6 sec
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4
Turn sharp left onto South Main Street
87 m · 11 sec · South Main Street
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5
Turn left onto West Terra Lane
576 ft · 12 sec · West Terra Lane
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6
Take the ramp straight toward I 70 West
146 m · 7 sec
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7
Merge slight left
6.9 mi · 8 min
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8
Take the exit slight right toward US 61 North: Hannibal
2234 ft · 48 sec
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9
Merge slight left onto Avenue of the Saints
73.3 mi · 1 hr 27 min · Avenue of the Saints
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10
Take the exit slight left
76 m · 15 sec
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11
Turn left onto Paris Gravel Road
2645 ft · 1 min · Paris Gravel Road
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12
Keep slight right to continue on County Road 422
85 m · 9 sec · County Road 422
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13
Turn right onto Veterans Road
3.2 mi · 6 min · Veterans Road
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14
Turn left
1.7 mi · 2 min
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15
Turn left onto Avenue of the Saints
17 mi · 20 min · Avenue of the Saints
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16
Take the exit slight right toward Avenue of the Saints
33.3 mi · 39 min · Avenue of the Saints
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17
Take the exit slight right toward US 136: Wayland, Kahoka
1561 ft · 48 sec
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18
Turn left
33.8 mi · 50 min
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19
Turn right onto South Market Street
2417 ft · 54 sec · South Market Street
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20
Turn left onto East Monroe Street
530 ft · 11 sec · East Monroe Street
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21
Arrive at your destination
0 m · 1 sec · West Monroe Street
Car Route Details
A richer read on the saved driving route between O'Fallon and Memphis.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Avenue of the Saints
Merge slight left onto Avenue of the Saints
73.3 mi · 01h 27m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving O'Fallon and Patchy Frost then Sunny near Memphis.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from O'Fallon to Memphis?
The road trip is about 171.9 miles (276.6 km) and usually takes 03h 38m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Hannibal is a useful midpoint, sitting about 85.9 miles from O'Fallon and 85.9 miles from Memphis.
How much longer is the road route than the straight-line distance?
The direct path is about 138.1 miles (222.3 km), while the road route adds roughly 33.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 9:42 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $22.85 one way or $45.70 round trip. Estimated CO2 is about 53.9 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around O'Fallon and Patchy Frost then Sunny near Memphis.
Stop Ideas Near Hannibal
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Hannibal.
Quincy
Fort Madison station
Macomb
La Plata
Flight Path Map
This map shows the direct air route between O'Fallon and Memphis. Straight-line distance: 138.14 mi (222.31 km).
#1 O'Fallon
The most populous city in St.
| Population | 89,769 |
| Coordinates | 38.8106100, -90.6998500 |
| Altitude | 165 |
| Country | United States |
#2 Memphis
City in Scotland County, Missouri, United States
| Population | 1,815 |
| Coordinates | 40.4578100, -92.1712900 |
| Altitude | 244 |
| Country | United States |
End: Memphis (-92.17129, 40.45781)
Estimated Travel Time
Distance: 277 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 43m |
| 40 mph (64.37 km/h) | 04h 17m |
| 50 mph (80.47 km/h) | 03h 26m |
| 60 mph (96.56 km/h) | 02h 51m |
| 70 mph (112.65 km/h) | 02h 27m |
| 80 mph (129 km/h) | 02h 08m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $22.85 | $45.70 |
| Mid-grade | $4.25 | $25.77 | $51.55 |
| Premium | $4.65 | $28.20 | $56.41 |
| Diesel | $5.30 | $32.14 | $64.28 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 02, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.