How far is Mayville, WI from La Crosse, WI?
The driving distance from Mayville, WI to La Crosse, WI is about 164 miles (264 km), with a travel time of about 02h 56m by car.
- The straight-line flight distance is about 136.4 miles (219.5 km).
- For a round trip, plan for roughly 05h 53m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 56m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Village in Juneau County, Wisconsin
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Mayville and La Crosse.
Turn-by-Turn Driving Directions
Step-by-step road directions between Mayville and La Crosse.
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1
Start on the route
75 m · 23 sec
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2
Turn left onto Allen Street
41 m · 11 sec · Allen Street
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3
Turn left onto South School Street
101 m · 17 sec · South School Street
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4
Turn right onto Horicon Street
1.6 km · 2 min · Horicon Street
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5
Continue on State Highway 28
4.3 mi · 8 min · State Highway 28
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6
At the end of the road, turn right onto West Lake Street
2487 ft · 49 sec · West Lake Street
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7
Turn left onto Vine Street
791 ft · 14 sec · Vine Street
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8
Continue on Barstow Street
1679 ft · 28 sec · Barstow Street
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9
Continue on Main Street
1296 ft · 24 sec · Main Street
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10
Turn right onto Washington Street
1 km · 57 sec · Washington Street
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11
Continue on State Highway 33
8 mi · 11 min · State Highway 33
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12
Continue on Park Avenue
2438 ft · 55 sec · Park Avenue
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13
Turn left
1614 ft · 39 sec
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14
Merge slight left
13.4 mi · 15 min
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15
Take the exit slight right toward WI 16, WI 60: Columbus, Portage
1758 ft · 43 sec
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16
Keep slight right
73 m · 6 sec
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17
Turn straight onto James Street
979 ft · 21 sec · James Street
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18
Continue on State Highway 16
22.7 mi · 31 min · State Highway 16
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19
Turn straight onto US Highway 51 & State Highway 16
2.7 mi · 4 min · US Highway 51 & State Highway 16
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20
Continue on East Wisconsin Street
1.6 mi · 4 min · East Wisconsin Street
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21
Turn left onto West Cook Street
3.7 mi · 5 min · West Cook Street
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22
Take the ramp slight right
2038 ft · 50 sec
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23
Merge slight left
60.2 mi · 1 hr 5 min
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24
Keep slight left to continue on I 90 West: Tomah, La Crosse
39.1 mi · 42 min
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25
Take the exit slight right toward WI 16: La Crosse, Onalaska
1636 ft · 42 sec
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26
At the end of the road, turn left
4.9 mi · 9 min
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27
Continue on Losey Boulevard North
2575 ft · 2 min · Losey Boulevard North
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28
Turn right onto Main Street
1.1 km · 2 min · Main Street
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29
Turn left onto 16th Street South
1.3 km · 2 min · 16th Street South
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30
Turn right onto Johnson Street
1824 ft · 1 min · Johnson Street
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31
At the end of the road, turn right onto West Avenue South
99 m · 11 sec · West Avenue South
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32
Arrive at your destination
0 m · 1 sec · West Avenue South
Car Route Details
A richer read on the saved driving route between Mayville and La Crosse.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
West Cook Street
Merge slight left
60.2 mi · 01h 05m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Sunny leaving Mayville and Sunny near La Crosse.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Mayville to La Crosse?
The road trip is about 164 miles (264 km) and usually takes 02h 56m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Lyndon Station is a useful midpoint, sitting about 83.8 miles from Mayville and 80.3 miles from La Crosse.
How much longer is the road route than the straight-line distance?
The direct path is about 136.4 miles (219.5 km), while the road route adds roughly 27.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 12:36 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $21.83 one way or $43.67 round trip. Estimated CO2 is about 51.5 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Mayville and Sunny near La Crosse.
Stop Ideas Near Lyndon Station
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Lyndon Station.
Wisconsin Dells
Portage
Westfield, WI
Tomah
Flight Path Map
This map shows the direct air route between Mayville and La Crosse. Straight-line distance: 136.38 mi (219.49 km).
#1 Mayville
City in Dodge County, Wisconsin, United States
| Population | 4,829 |
| Coordinates | 43.4941600, -88.5448200 |
| Altitude | 283 |
| Country | United States |
#2 La Crosse
The most populous city in La Crosse County, Wisconsin.
| Population | 51,163 |
| Coordinates | 43.8013600, -91.2395800 |
| Altitude | 204 |
| Country | United States |
End: West Avenue South (-91.239623, 43.801338)
Estimated Travel Time
Distance: 264 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 27m |
| 40 mph (64.37 km/h) | 04h 06m |
| 50 mph (80.47 km/h) | 03h 16m |
| 60 mph (96.56 km/h) | 02h 44m |
| 70 mph (112.65 km/h) | 02h 20m |
| 80 mph (129 km/h) | 02h 02m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $21.83 | $43.67 |
| Mid-grade | $4.25 | $24.62 | $49.25 |
| Premium | $4.65 | $26.95 | $53.89 |
| Diesel | $5.30 | $30.71 | $61.42 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Wisconsin · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.