How far is Lenexa, KS from Medicine Lodge, KS?
The driving distance from Lenexa, KS to Medicine Lodge, KS is about 265.7 miles (427.6 km), with a travel time of about 05h 22m by car.
- The straight-line flight distance is about 238.9 miles (384.4 km).
- For a round trip, plan for roughly 10h 45m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 22m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Butler County, Kansas, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Lenexa and Medicine Lodge.
Turn-by-Turn Driving Directions
Step-by-step road directions between Lenexa and Medicine Lodge.
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1
Start on the route
78 m · 21 sec
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2
Turn right
22 m · 10 sec
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3
Turn left onto Rosehill Road
152 m · 21 sec · Rosehill Road
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4
Turn right onto Lenexa Drive
635 ft · 31 sec · Lenexa Drive
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5
Continue on Lenexa Drive
757 ft · 34 sec · Lenexa Drive
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6
Turn right onto West 95th Street
1033 ft · 20 sec · West 95th Street
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7
Take the ramp slight left toward I 35 South, US 56 West, US 169 South: Wichita
908 ft · 22 sec
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8
Merge slight left
1.7 mi · 2 min
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9
Continue straight
37.1 mi · 39 min
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10
Continue straight
132.8 mi · 2 hr 14 min
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11
Take the exit slight right toward US 54, US 400
2804 ft · 1 min
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12
Merge slight left onto Vietnam Veterans Memorial Highway
11.4 mi · 14 min · Vietnam Veterans Memorial Highway
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13
Take the exit slight right toward I 235 South
953 ft · 24 sec
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14
Merge slight left
1.6 mi · 2 min
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15
Take the exit slight right toward KS 42
1487 ft · 36 sec
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16
Turn right onto West Southwest Boulevard
2633 ft · 55 sec · West Southwest Boulevard
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17
Continue on West Cessna Boulevard
1.1 mi · 2 min · West Cessna Boulevard
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18
Continue on West Southwest Boulevard
7.2 mi · 9 min · West Southwest Boulevard
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19
Continue on State Highway 42
17.3 mi · 31 min · State Highway 42
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20
Turn left
17.7 mi · 31 min
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21
At the end of the road, turn right onto East 14th Street
1.1 mi · 2 min · East 14th Street
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22
Turn left
3 mi · 5 min
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23
Turn right
30.9 mi · 46 min
-
24
Turn right onto South Main Street
1758 ft · 54 sec · South Main Street
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25
Turn left onto West Kansas Avenue
131 m · 21 sec · West Kansas Avenue
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26
Turn right onto North Cherry Street
64 m · 12 sec · North Cherry Street
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27
Turn right
47 m · 11 sec
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28
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Lenexa and Medicine Lodge.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 35 South
Continue straight
133 mi · 02h 14m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Lenexa and Sunny near Medicine Lodge.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Lenexa to Medicine Lodge?
The road trip is about 265.7 miles (427.6 km) and usually takes 05h 22m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Cassoday is a useful midpoint, sitting about 132.7 miles from Lenexa and 133 miles from Medicine Lodge.
How much longer is the road route than the straight-line distance?
The direct path is about 238.9 miles (384.4 km), while the road route adds roughly 26.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 6:14 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $35.37 one way or $70.74 round trip. Estimated CO2 is about 83.4 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Lenexa and Sunny near Medicine Lodge.
Stop Ideas Near Cassoday
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Cassoday.
Newton
Hutchinson
Flight Path Map
This map shows the direct air route between Lenexa and Medicine Lodge. Straight-line distance: 238.88 mi (384.44 km).
#1 Lenexa
The most populous city in Johnson County, Kansas.
| Population | 56,156 |
| Coordinates | 38.9536200, -94.7335700 |
| Altitude | 314 |
| Country | United States |
#2 Medicine Lodge
City in Barber County, Kansas, United States
| Population | 1,804 |
| Coordinates | 37.2811300, -98.5803600 |
| Altitude | 456 |
| Country | United States |
End: Medicine Lodge (-98.58036, 37.28113)
Estimated Travel Time
Distance: 428 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 51m |
| 40 mph (64.37 km/h) | 06h 38m |
| 50 mph (80.47 km/h) | 05h 18m |
| 60 mph (96.56 km/h) | 04h 25m |
| 70 mph (112.65 km/h) | 03h 47m |
| 80 mph (129 km/h) | 03h 18m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $35.37 | $70.74 |
| Mid-grade | $4.25 | $39.89 | $79.79 |
| Premium | $4.65 | $43.65 | $87.31 |
| Diesel | $5.30 | $49.75 | $99.50 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Kansas · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.