How far is Knoxville, TN from Waynesboro, TN?
The driving distance from Knoxville, TN to Waynesboro, TN is about 275.2 miles (442.9 km), with a travel time of about 05h 13m by car.
- The straight-line flight distance is about 220.2 miles (354.4 km).
- For a round trip, plan for roughly 10h 27m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 13m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Wilson County, Tennessee, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Knoxville and Waynesboro.
Turn-by-Turn Driving Directions
Step-by-step road directions between Knoxville and Waynesboro.
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1
Start on Henley Street
1056 ft · 20 sec · Henley Street
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2
Continue on Henley Street
727 ft · 14 sec · Henley Street
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3
Turn slight left onto Western Avenue
1.1 km · 1 min · Western Avenue
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4
Turn left onto Ailor Avenue
2326 ft · 43 sec · Ailor Avenue
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5
Take the ramp straight toward I 40 West, I 75 South
1637 ft · 40 sec
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6
Merge slight left
18.3 mi · 21 min
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7
Keep slight right to continue on Nashville
132.7 mi · 2 hr 23 min
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8
Take the exit slight right toward I 840 West: Memphis, Murfreesboro
1.1 mi · 1 min
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9
Continue on Tennessee National Guard Parkway
44.6 mi · 48 min · Tennessee National Guard Parkway
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10
Take the exit slight right toward I 65: Nashville, Huntsville
1805 ft · 22 sec
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11
Keep slight left to continue on I 65 South: Huntsville
1.6 mi · 3 min
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12
Merge slight left
11.5 mi · 12 min
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13
Take the exit slight right toward 412, 99: Columbia, Chapel Hill
1053 ft · 23 sec
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14
Keep slight right to continue on 412: Columbia
49 m · 5 sec
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15
Turn right onto Bear Creek Pike
30.2 mi · 35 min · Bear Creek Pike
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16
Turn right
1.1 km · 1 min
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17
Continue straight
1.3 mi · 2 min
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18
Turn slight left
10 mi · 18 min
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19
Continue straight
4.9 mi · 9 min
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20
Turn right onto Waynesboro Highway
14.4 mi · 16 min · Waynesboro Highway
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21
Continue on Dexter L Woods Memorial Boulevard
1.3 mi · 2 min · Dexter L Woods Memorial Boulevard
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22
At the end of the road, turn right onto Hill Street
58 m · 4 sec · Hill Street
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23
Turn left onto West Public Square
92 m · 7 sec · West Public Square
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24
At the end of the road, turn left onto Hollis Street
65 m · 4 sec · Hollis Street
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25
Turn left onto North Main Street
18 m · 1 sec · North Main Street
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26
Arrive at your destination
0 m · 1 sec · North Main Street
Car Route Details
A richer read on the saved driving route between Knoxville and Waynesboro.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Nashville
Keep slight right to continue on Nashville
133 mi · 02h 23m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Knoxville and Sunny near Waynesboro.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Knoxville to Waynesboro?
The road trip is about 275.2 miles (442.9 km) and usually takes 05h 13m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Watertown is a useful midpoint, sitting about 137.4 miles from Knoxville and 137.8 miles from Waynesboro.
How much longer is the road route than the straight-line distance?
The direct path is about 220.2 miles (354.4 km), while the road route adds roughly 55 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 6:32 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $36.62 one way or $73.23 round trip. Estimated CO2 is about 86.3 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Knoxville and Waynesboro, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Sunny around Knoxville and Sunny near Waynesboro.
Stop Ideas Near Watertown
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Watertown.
Nashville, TN
Flight Path Map
This map shows the direct air route between Knoxville and Waynesboro. Straight-line distance: 220.2 mi (354.37 km).
#1 Knoxville
The most populous city in Tennessee.
| Population | 190,223 |
| Coordinates | 35.9606400, -83.9207400 |
| Altitude | 276 |
| Country | United States |
#2 Waynesboro
City in Tennessee
| Population | 2,371 |
| Coordinates | 35.3195200, -87.7622500 |
| Altitude | 228 |
| Country | United States |
End: Waynesboro (-87.76225, 35.31952)
Estimated Travel Time
Distance: 443 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 10m |
| 40 mph (64.37 km/h) | 06h 52m |
| 50 mph (80.47 km/h) | 05h 30m |
| 60 mph (96.56 km/h) | 04h 35m |
| 70 mph (112.65 km/h) | 03h 55m |
| 80 mph (129 km/h) | 03h 25m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $36.62 | $73.23 |
| Mid-grade | $4.25 | $41.30 | $82.59 |
| Premium | $4.65 | $45.19 | $90.38 |
| Diesel | $5.30 | $51.50 | $103.00 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Tennessee · May 13, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.