How far is Key West, FL from Port Saint Lucie, FL?
The driving distance from Key West, FL to Port Saint Lucie, FL is about 275 miles (442.6 km), with a travel time of about 05h 00m by car.
- The straight-line flight distance is about 209.1 miles (336.5 km).
- For a round trip, plan for roughly 10h 00m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 00m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census-designated place in Miami-Dade County, Florida
Route Weather Snapshot
Check the forecast at both ends before you head out.
Slight Chance Showers And Thunderstorms then Chance Showers And Thunderstorms
Mostly Sunny then Slight Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Key West and Port Saint Lucie.
Turn-by-Turn Driving Directions
Step-by-step road directions between Key West and Port Saint Lucie.
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1
Start on George Street
112 m · 21 sec · George Street
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2
At the end of the road, turn left onto Flagler Avenue
2.1 mi · 5 min · Flagler Avenue
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3
At the end of the road, turn left onto South Roosevelt Boulevard
1367 ft · 41 sec · South Roosevelt Boulevard
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4
Turn right onto Overseas Highway
36.1 mi · 57 min · Overseas Highway
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5
Continue on New Seven Mile Bridge
68.1 mi · 1 hr 46 min · New Seven Mile Bridge
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6
Continue on Dixie Highway
19.4 mi · 27 min · Dixie Highway
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7
Take the exit slight right toward Miami, Orlando, Florida's Turnpike North
1785 ft · 38 sec
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8
Continue on Homestead Extension of Florida's Turnpike
13.2 mi · 16 min · Homestead Extension of Florida's Turnpike
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9
Keep slight right to continue on Homestead Extension of Florida's Turnpike
3.6 mi · 5 min · Homestead Extension of Florida's Turnpike
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10
Keep slight left to continue on Homestead Extension of Florida's Turnpike
2.5 mi · 3 min · Homestead Extension of Florida's Turnpike
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11
Keep slight right to continue on Homestead Extension of Florida's Turnpike
27.1 mi · 30 min · Homestead Extension of Florida's Turnpike
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12
Keep slight right to continue on Homestead Extension of Florida's Turnpike
1 mi · 1 min · Homestead Extension of Florida's Turnpike
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13
Merge slight left onto Florida's Turnpike
95.2 mi · 1 hr 46 min · Florida's Turnpike
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14
Take the exit slight right toward Port Saint Lucie
1.3 km · 2 min
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15
Continue on Southwest Bayshore Boulevard
147 m · 15 sec · Southwest Bayshore Boulevard
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16
Turn right onto Southwest Port Saint Lucie Boulevard
1.4 km · 2 min · Southwest Port Saint Lucie Boulevard
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17
Turn left onto Southeast Airoso Boulevard
1.6 mi · 3 min · Southeast Airoso Boulevard
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18
Turn left onto Southwest Carter Avenue
66 m · 9 sec · Southwest Carter Avenue
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19
Arrive at your destination
0 m · 1 sec · Southwest Carter Avenue
Car Route Details
A richer read on the saved driving route between Key West and Port Saint Lucie.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Florida's Turnpike
Merge slight left onto Florida's Turnpike
95.2 mi · 01h 46m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Slight Chance Showers And Thunderstorms then Chance Showers And Thunderstorms leaving Key West and Mostly Sunny then Slight Chance Showers And Thunderstorms near Port Saint Lucie.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Key West to Port Saint Lucie?
The road trip is about 275 miles (442.6 km) and usually takes 05h 00m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Goulds is a useful midpoint, sitting about 136.3 miles from Key West and 138.7 miles from Port Saint Lucie.
How much longer is the road route than the straight-line distance?
The direct path is about 209.1 miles (336.5 km), while the road route adds roughly 65.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 7:00 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $40.28 one way or $80.55 round trip. Estimated CO2 is about 86.3 kg one way.
What should you check before leaving?
Before you leave, expect Slight Chance Showers And Thunderstorms then Chance Showers And Thunderstorms around Key West and Mostly Sunny then Slight Chance Showers And Thunderstorms near Port Saint Lucie.
Stop Ideas Near Goulds
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
City Hall Bistro & Martini Bar
Historic Homestead Town Hall Museum
Miami City Hall
Homestead Building & Zoning
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Goulds.
Miami Intermodal Center
Hollywood
Fort Lauderdale
Deerfield Beach
Flight Path Map
This map shows the direct air route between Key West and Port Saint Lucie. Straight-line distance: 209.08 mi (336.48 km).
#1 Key West
County seat city of Monroe County, Florida, United States; island in Florida Keys
| Population | 23,767 |
| Coordinates | 24.5552400, -81.7816300 |
| Altitude | 1 |
| Country | United States |
#2 Port Saint Lucie
The second most populous city in St.
| Population | 209,715 |
| Coordinates | 27.2939300, -80.3503300 |
| Altitude | 5 |
| Country | United States |
End: Southwest Carter Avenue (-80.350328, 27.294381)
Estimated Travel Time
Distance: 443 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 09m |
| 40 mph (64.37 km/h) | 06h 52m |
| 50 mph (80.47 km/h) | 05h 30m |
| 60 mph (96.56 km/h) | 04h 35m |
| 70 mph (112.65 km/h) | 03h 55m |
| 80 mph (129 km/h) | 03h 25m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $40.28 | $80.55 |
| Mid-grade | $4.60 | $44.63 | $89.25 |
| Premium | $4.90 | $47.54 | $95.08 |
| Diesel | $4.35 | $42.24 | $84.48 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · May 26, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.