How far is Hilton Head Island, SC from Greenville, SC?
The driving distance from Hilton Head Island, SC to Greenville, SC is about 263.4 miles (423.9 km), with a travel time of about 03h 59m by car.
- The straight-line flight distance is about 207 miles (333.1 km).
- For a round trip, plan for roughly 07h 59m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 59m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Calhoun County, South Carolina
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms then Showers And Thunderstorms
Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between Hilton Head Island and Greenville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Hilton Head Island and Greenville.
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1
Start on Allen Road
887 ft · 42 sec · Allen Road
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2
Turn left onto Marshland Road
2.2 mi · 5 min · Marshland Road
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3
Take the ramp right
2176 ft · 53 sec
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4
Merge slight left onto Cross Island Parkway
2.3 mi · 2 min · Cross Island Parkway
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5
Merge slight left onto William Hilton Parkway
3.9 mi · 4 min · William Hilton Parkway
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6
Continue on Fording Island Road
9 mi · 13 min · Fording Island Road
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7
Take the exit slight right
1444 ft · 40 sec
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8
Keep slight right
45 m · 4 sec
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9
Merge slight left onto Okatie Highway
3.9 mi · 5 min · Okatie Highway
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10
Take the exit slight left
149 m · 14 sec
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11
Continue on Lowcountry Drive
7.9 mi · 11 min · Lowcountry Drive
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12
Continue on Coosaw Scenic Drive
9.4 mi · 13 min · Coosaw Scenic Drive
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13
Take the ramp slight right toward I 95 North, US 17 North: Florence
1435 ft · 35 sec
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14
Merge slight left
57.2 mi · 1 hr 1 min
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15
Take the exit slight right toward I 26 West: Columbia
1864 ft · 1 min
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16
Merge slight left
116.6 mi · 2 hr 7 min
-
17
Keep slight left to continue on I 385 North: Laurens, Greenville
29.6 mi · 32 min
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18
Keep slight left to continue on Golden Strip Freeway
12.4 mi · 15 min · Golden Strip Freeway
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19
Continue on East North Street
1270 ft · 19 sec · East North Street
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20
Continue on Beattie Place
1231 ft · 27 sec · Beattie Place
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21
Turn right onto North Church Street
18 m · 2 sec · North Church Street
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22
Arrive at your destination
0 m · 1 sec · North Church Street
Car Route Details
A richer read on the saved driving route between Hilton Head Island and Greenville.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 26 West
Merge slight left
117 mi · 02h 07m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Showers And Thunderstorms then Showers And Thunderstorms leaving Hilton Head Island and Showers And Thunderstorms Likely near Greenville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Hilton Head Island to Greenville?
The road trip is about 263.4 miles (423.9 km) and usually takes 03h 59m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Saint Matthews is a useful midpoint, sitting about 128.3 miles from Hilton Head Island and 135.1 miles from Greenville.
How much longer is the road route than the straight-line distance?
The direct path is about 207 miles (333.1 km), while the road route adds roughly 56.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 9:00 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $36.80 one way or $73.60 round trip. Estimated CO2 is about 82.6 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms then Showers And Thunderstorms around Hilton Head Island and Showers And Thunderstorms Likely near Greenville.
Stop Ideas Near Saint Matthews
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Saint Matthews.
Columbia
Denmark
Camden
Kingstree
Flight Path Map
This map shows the direct air route between Hilton Head Island and Greenville. Straight-line distance: 206.98 mi (333.1 km).
#1 Hilton Head Island
Resort town in South Carolina, USA
| Population | 39,619 |
| Coordinates | 32.1938200, -80.7381600 |
| Altitude | 3 |
| Country | United States |
#2 Greenville
The most populous city in Greenville County, South Carolina.
| Population | 72,227 |
| Coordinates | 34.8526200, -82.3940100 |
| Altitude | 307 |
| Country | United States |
End: North Church Street (-82.394165, 34.852668)
Estimated Travel Time
Distance: 424 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 46m |
| 40 mph (64.37 km/h) | 06h 35m |
| 50 mph (80.47 km/h) | 05h 16m |
| 60 mph (96.56 km/h) | 04h 23m |
| 70 mph (112.65 km/h) | 03h 45m |
| 80 mph (129 km/h) | 03h 17m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $36.80 | $73.60 |
| Mid-grade | $4.43 | $41.15 | $82.29 |
| Premium | $4.78 | $44.39 | $88.78 |
| Diesel | $5.62 | $52.25 | $104.49 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in South Carolina · May 30, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.