How far is Guadalupe, CA from San Diego, CA?
The driving distance from Guadalupe, CA to San Diego, CA is about 289.7 miles (466.3 km), with a travel time of about 04h 42m by car.
- The straight-line flight distance is about 250 miles (402.4 km).
- For a round trip, plan for roughly 09h 25m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM PDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 42m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
The third most populous city in Santa Barbara County, California.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Guadalupe and San Diego.
Turn-by-Turn Driving Directions
Step-by-step road directions between Guadalupe and San Diego.
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1
Start on 10th Street
37 m · 11 sec · 10th Street
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2
Turn left onto Guadalupe Street
1.6 km · 1 min · Guadalupe Street
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3
Continue on Cabrillo Highway
9.9 mi · 14 min · Cabrillo Highway
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4
Turn left onto West Clark Avenue
3.4 mi · 6 min · West Clark Avenue
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5
Take the ramp right
1375 ft · 34 sec
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6
Merge slight left
18.6 mi · 21 min
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7
Take the exit slight right toward CA 154: Los Olivos, Lake Cachuma
1266 ft · 37 sec
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8
Turn left onto Chumash Highway
6.4 mi · 10 min · Chumash Highway
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9
Enter the roundabout and take exit 2 toward Chumash Highway
39 m · 2 sec · Chumash Highway
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10
Exit the roundabout onto Chumash Highway
2.2 mi · 3 min · Chumash Highway
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11
Enter the roundabout and take exit 2 toward Chumash Highway
35 m · 2 sec · Chumash Highway
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12
Exit the roundabout onto Chumash Highway
23.9 mi · 33 min · Chumash Highway
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13
Take the ramp slight left toward US 101 South
1206 ft · 32 sec
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14
Merge slight left onto El Camino Real
17 mi · 20 min · El Camino Real
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15
Continue on Ventura Freeway
65.2 mi · 1 hr 15 min · Ventura Freeway
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16
Take the exit slight right toward I 405 North, I 405 South: Sacramento, Santa Monica
758 ft · 19 sec
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17
Keep slight right to continue on I 405 South: San Diego Freeway, Santa Monica
1584 ft · 39 sec
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18
Keep slight left to continue on I 405 South: San Diego Freeway
553 ft · 14 sec
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19
Merge slight left onto San Diego Freeway
13.3 mi · 15 min · San Diego Freeway
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20
Keep slight right to continue on San Diego Freeway
26.5 mi · 31 min · San Diego Freeway
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21
Keep slight right to continue on San Diego Freeway
2.3 mi · 3 min · San Diego Freeway
-
22
Keep slight left to continue on San Diego Freeway
893 ft · 12 sec · San Diego Freeway
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23
Keep slight left
10.3 mi · 12 min
-
24
Keep slight right to continue on Corona Del Mar Freeway
4 mi · 5 min · Corona Del Mar Freeway
-
25
Continue on San Joaquin Hills Transportation Corridor
10.3 mi · 12 min · San Joaquin Hills Transportation Corridor
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26
Take the exit slight right toward La Paz Road, Moulton Parkway
133 m · 6 sec
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27
Keep slight left to continue on CA 73 South: Moulton Parkway
2519 ft · 33 sec
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28
Keep slight left to continue on CA 73 South
3218 ft · 42 sec
-
29
Merge slight left onto San Joaquin Hills Transportation Corridor
2.5 mi · 3 min · San Joaquin Hills Transportation Corridor
-
30
Merge slight left onto San Diego Freeway
67.8 mi · 1 hr 19 min · San Diego Freeway
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31
Take the exit slight right toward Front Street, Civic Center, 2nd Avenue
1164 ft · 28 sec
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32
Keep slight right to continue on Front Street, Civic Center
592 ft · 15 sec
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33
Continue on Front Street
2662 ft · 2 min · Front Street
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34
Arrive at your destination
0 m · 1 sec · Front Street
Car Route Details
A richer read on the saved driving route between Guadalupe and San Diego.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
San Diego Freeway
Merge slight left onto San Diego Freeway
67.8 mi · 01h 19m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Guadalupe and Mostly Sunny near San Diego.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Guadalupe to San Diego?
The road trip is about 289.7 miles (466.3 km) and usually takes 04h 42m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Santa Maria is a useful midpoint, sitting about 144 miles from Guadalupe and 145.8 miles from San Diego.
How much longer is the road route than the straight-line distance?
The direct path is about 250 miles (402.4 km), while the road route adds roughly 39.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM PDT. If you want a more comfortable same-day return, try to leave by 7:34 AM PDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $58.96 one way or $117.92 round trip. Estimated CO2 is about 90.8 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Guadalupe and Mostly Sunny near San Diego.
Stop Ideas Near Santa Maria
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Beverly Wilshire, A Four Seasons Hotel
City of Beverly Hills Parking Lot
Topanga Canyon Town Council
City of Santa Clarita: Newhall Community Center
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Santa Maria.
Westwood-UCLA, CA
Chatsworth station
Van Nuys station
Simi Valley
Flight Path Map
This map shows the direct air route between Guadalupe and San Diego. Straight-line distance: 250.01 mi (402.36 km).
#1 Guadalupe
City in Santa Barbara County, California
| Population | 8,140 |
| Coordinates | 34.9716400, -120.5718400 |
| Altitude | 26 |
| Country | United States |
#2 San Diego
The eighth most populous city in the United States and the center of the San Diego metropolitan area.
| Population | 1,422,420 |
| Coordinates | 32.7157100, -117.1647200 |
| Altitude | 20 |
| Country | United States |
End: Front Street (-117.164717, 32.71571)
Estimated Travel Time
Distance: 466 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 39m |
| 40 mph (64.37 km/h) | 07h 14m |
| 50 mph (80.47 km/h) | 05h 47m |
| 60 mph (96.56 km/h) | 04h 49m |
| 70 mph (112.65 km/h) | 04h 08m |
| 80 mph (129 km/h) | 03h 36m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $5.77 | $58.96 | $117.92 |
| Mid-grade | $6.07 | $61.99 | $123.99 |
| Premium | $6.24 | $63.80 | $127.61 |
| Diesel | $7.57 | $77.33 | $154.67 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in California · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.