How far is Guadalupe, CA from Santa Ana, CA?
The driving distance from Guadalupe, CA to Santa Ana, CA is about 205.2 miles (330.3 km), with a travel time of about 03h 32m by car.
- The straight-line flight distance is about 176 miles (283.2 km).
- For a round trip, plan for roughly 07h 04m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM PDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 32m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
The most populous city in Ventura County, California.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Patchy Fog
Partly Sunny
Driving Route Map
The map below follows the saved road route between Guadalupe and Santa Ana.
Turn-by-Turn Driving Directions
Step-by-step road directions between Guadalupe and Santa Ana.
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1
Start on 10th Street
37 m · 11 sec · 10th Street
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2
Turn left onto Guadalupe Street
1.6 km · 1 min · Guadalupe Street
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3
Continue on Cabrillo Highway
9.9 mi · 14 min · Cabrillo Highway
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4
Turn left onto West Clark Avenue
3.4 mi · 6 min · West Clark Avenue
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5
Take the ramp right
1375 ft · 34 sec
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6
Merge slight left
18.6 mi · 21 min
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7
Take the exit slight right toward CA 154: Los Olivos, Lake Cachuma
1266 ft · 39 sec
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8
Turn left onto Chumash Highway
6.4 mi · 10 min · Chumash Highway
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9
Enter the roundabout and take exit 2 toward Chumash Highway
39 m · 2 sec · Chumash Highway
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10
Exit the roundabout onto Chumash Highway
2.2 mi · 3 min · Chumash Highway
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11
Enter the roundabout and take exit 2 toward Chumash Highway
35 m · 2 sec · Chumash Highway
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12
Exit the roundabout onto Chumash Highway
23.9 mi · 33 min · Chumash Highway
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13
Take the ramp slight left toward US 101 South
1206 ft · 32 sec
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14
Merge slight left onto El Camino Real
17 mi · 20 min · El Camino Real
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15
Continue on Ventura Freeway
70.5 mi · 1 hr 21 min · Ventura Freeway
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16
Keep slight right to continue on Route 101
1 km · 44 sec · Route 101
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17
Merge slight left onto Hollywood Freeway
10.3 mi · 14 min · Hollywood Freeway
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18
Continue on Santa Ana Freeway
29.4 mi · 35 min · Santa Ana Freeway
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19
Keep slight right to continue on Santa Ana Freeway
1241 ft · 16 sec · Santa Ana Freeway
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20
Take the exit slight right toward Broadway, Main Street, Santa Ana
1.3 km · 57 sec
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21
Keep slight right to continue on Main Street North, Broadway
1656 ft · 22 sec
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22
Turn straight onto North Broadway
1.3 mi · 3 min · North Broadway
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23
Turn left onto West 5th Street
639 ft · 17 sec · West 5th Street
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24
Turn right onto North Main Street
1209 ft · 31 sec · North Main Street
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25
Turn right onto West 1st Street
16 m · 1 sec · West 1st Street
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26
Arrive at your destination
0 m · 1 sec · West 1st Street
Car Route Details
A richer read on the saved driving route between Guadalupe and Santa Ana.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Ventura Freeway
Continue on Ventura Freeway
70.5 mi · 01h 21m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Patchy Fog leaving Guadalupe and Partly Sunny near Santa Ana.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Guadalupe to Santa Ana?
The road trip is about 205.2 miles (330.3 km) and usually takes 03h 32m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Ventura is a useful midpoint, sitting about 98.4 miles from Guadalupe and 106.8 miles from Santa Ana.
How much longer is the road route than the straight-line distance?
The direct path is about 176 miles (283.2 km), while the road route adds roughly 29.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM PDT. If you want a more comfortable same-day return, try to leave by 9:56 AM PDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $41.77 one way or $83.54 round trip. Estimated CO2 is about 64.3 kg one way.
What should you check before leaving?
Before you leave, expect Patchy Fog around Guadalupe and Partly Sunny near Santa Ana.
Stop Ideas Near Ventura
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Bella Capri Inn & Suites
Hampton Inn & Suites Camarillo
Ventura City Hall (formerly the Ventura County Courthouse - California Historical Landmark #847)
San Buenaventura City Hall
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Ventura.
Ventura
Oxnard Transportation Center
Santa Paula, California
Carpinteria station
Flight Path Map
This map shows the direct air route between Guadalupe and Santa Ana. Straight-line distance: 175.95 mi (283.17 km).
#1 Guadalupe
City in Santa Barbara County, California
| Population | 8,140 |
| Coordinates | 34.9716400, -120.5718400 |
| Altitude | 26 |
| Country | United States |
#2 Santa Ana
The most populous city in Orange County, California and the center of the Santa Ana metropolitan area.
| Population | 331,301 |
| Coordinates | 33.7455700, -117.8678300 |
| Altitude | 35 |
| Country | United States |
End: West 1st Street (-117.86783, 33.745553)
Estimated Travel Time
Distance: 330 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 50m |
| 40 mph (64.37 km/h) | 05h 07m |
| 50 mph (80.47 km/h) | 04h 06m |
| 60 mph (96.56 km/h) | 03h 25m |
| 70 mph (112.65 km/h) | 02h 55m |
| 80 mph (129 km/h) | 02h 33m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $5.77 | $41.77 | $83.54 |
| Mid-grade | $6.07 | $43.92 | $87.84 |
| Premium | $6.24 | $45.20 | $90.40 |
| Diesel | $7.57 | $54.79 | $109.57 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in California · May 12, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.