How far is Greenville, SC from Myrtle Beach, SC?
The driving distance from Greenville, SC to Myrtle Beach, SC is about 253.6 miles (408.1 km), with a travel time of about 04h 00m by car.
- The straight-line flight distance is about 215.8 miles (347.3 km).
- For a round trip, plan for roughly 08h 01m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 00m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census-designated place in Kershaw County, South Carolina
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Rain Showers
Partly Sunny then Slight Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Greenville and Myrtle Beach.
Turn-by-Turn Driving Directions
Step-by-step road directions between Greenville and Myrtle Beach.
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1
Start on North Church Street
151 m · 21 sec · North Church Street
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2
Turn left onto East North Street
2612 ft · 43 sec · East North Street
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3
Continue straight
10.5 mi · 13 min
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4
Keep slight left to continue on Golden Strip Freeway
31.6 mi · 35 min · Golden Strip Freeway
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5
Merge slight left
55.2 mi · 1 hr
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6
Take the exit slight right toward I 20 East: Florence
1687 ft · 41 sec
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7
Merge slight left
79.4 mi · 1 hr 30 min
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8
Turn left onto West Palmetto Street
22.6 mi · 33 min · West Palmetto Street
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9
Continue straight
3.1 mi · 4 min
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10
Continue straight
41.9 mi · 55 min
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11
Turn straight
2 mi · 4 min
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12
Turn slight right onto 8th Avenue North
76 m · 15 sec · 8th Avenue North
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13
Turn right onto North Kings Highway
1443 ft · 41 sec · North Kings Highway
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14
Turn left onto 5th Avenue North
61 m · 11 sec · 5th Avenue North
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15
Turn right
60 m · 14 sec
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16
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Greenville and Myrtle Beach.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 20 East
Merge slight left
79.4 mi · 01h 30m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Rain Showers leaving Greenville and Partly Sunny then Slight Chance Showers And Thunderstorms near Myrtle Beach.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Greenville to Myrtle Beach?
The road trip is about 253.6 miles (408.1 km) and usually takes 04h 00m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Lugoff is a useful midpoint, sitting about 123.7 miles from Greenville and 129.9 miles from Myrtle Beach.
How much longer is the road route than the straight-line distance?
The direct path is about 215.8 miles (347.3 km), while the road route adds roughly 37.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 8:58 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $35.45 one way or $70.90 round trip. Estimated CO2 is about 79.5 kg one way.
What should you check before leaving?
Before you leave, expect Chance Rain Showers around Greenville and Partly Sunny then Slight Chance Showers And Thunderstorms near Myrtle Beach.
Stop Ideas Near Lugoff
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Lugoff.
Camden
Columbia
Florence
Kingstree
Flight Path Map
This map shows the direct air route between Greenville and Myrtle Beach. Straight-line distance: 215.78 mi (347.26 km).
#1 Greenville
The most populous city in Greenville County, South Carolina.
| Population | 72,227 |
| Coordinates | 34.8526200, -82.3940100 |
| Altitude | 307 |
| Country | United States |
#2 Myrtle Beach
Coastal city in South Carolina, United States
| Population | 35,555 |
| Coordinates | 33.6890600, -78.8866900 |
| Altitude | 8 |
| Country | United States |
End: North Kings Highway (-78.887105, 33.689329)
Estimated Travel Time
Distance: 408 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 26m |
| 40 mph (64.37 km/h) | 06h 20m |
| 50 mph (80.47 km/h) | 05h 04m |
| 60 mph (96.56 km/h) | 04h 13m |
| 70 mph (112.65 km/h) | 03h 37m |
| 80 mph (129 km/h) | 03h 09m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $35.45 | $70.90 |
| Mid-grade | $4.43 | $39.64 | $79.28 |
| Premium | $4.78 | $42.76 | $85.53 |
| Diesel | $5.62 | $50.33 | $100.67 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in South Carolina · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.