How far is Greenville, SC from Bluffton, SC?
The driving distance from Greenville, SC to Bluffton, SC is about 245.8 miles (395.5 km), with a travel time of about 04h 38m by car.
- The straight-line flight distance is about 201.1 miles (323.7 km).
- For a round trip, plan for roughly 09h 17m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 38m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Calhoun County, South Carolina
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Greenville and Bluffton.
Turn-by-Turn Driving Directions
Step-by-step road directions between Greenville and Bluffton.
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1
Start on North Church Street
151 m · 21 sec · North Church Street
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2
Turn left onto East North Street
2612 ft · 43 sec · East North Street
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3
Continue straight
10.5 mi · 13 min
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4
Keep slight left to continue on Golden Strip Freeway
31.6 mi · 35 min · Golden Strip Freeway
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5
Merge slight left
55.8 mi · 1 hr 1 min
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6
Keep slight right to continue on Charleston
60.2 mi · 1 hr 6 min
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7
Take the exit slight right toward I 95 South: Savannah
1.4 km · 2 min
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8
Merge slight left
56.6 mi · 1 hr 1 min
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9
Take the exit slight right toward SC 462: Coosawhatchie
1478 ft · 37 sec
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10
Turn left onto Coosaw Scenic Drive
9.6 mi · 13 min · Coosaw Scenic Drive
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11
Continue on Lowcountry Drive
7.9 mi · 11 min · Lowcountry Drive
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12
Turn right onto Okatie Highway
4.2 mi · 5 min · Okatie Highway
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13
Take the exit slight right
1365 ft · 37 sec
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14
Merge slight left onto Fording Island Road
5.8 mi · 7 min · Fording Island Road
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15
Turn right onto Bluffton Road
1.3 km · 1 min · Bluffton Road
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16
Enter the roundabout and take exit 2 toward Bluffton Road
52 m · 4 sec · Bluffton Road
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17
Exit the roundabout onto Bluffton Road
1.4 km · 2 min · Bluffton Road
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18
Turn left onto Bruin Road
27 m · 2 sec · Bruin Road
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19
Arrive at your destination
0 m · 1 sec · Bruin Road
Car Route Details
A richer read on the saved driving route between Greenville and Bluffton.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Charleston
Keep slight right to continue on Charleston
60.2 mi · 01h 06m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Greenville and Mostly Sunny near Bluffton.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Greenville to Bluffton?
The road trip is about 245.8 miles (395.5 km) and usually takes 04h 38m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Saint Matthews is a useful midpoint, sitting about 123 miles from Greenville and 122.8 miles from Bluffton.
How much longer is the road route than the straight-line distance?
The direct path is about 201.1 miles (323.7 km), while the road route adds roughly 44.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 7:42 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $34.34 one way or $68.68 round trip. Estimated CO2 is about 77.1 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Greenville and Mostly Sunny near Bluffton.
Stop Ideas Near Saint Matthews
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Saint Matthews.
Columbia
Denmark
Camden
Kingstree
Flight Path Map
This map shows the direct air route between Greenville and Bluffton. Straight-line distance: 201.13 mi (323.69 km).
#1 Greenville
The most populous city in Greenville County, South Carolina.
| Population | 72,227 |
| Coordinates | 34.8526200, -82.3940100 |
| Altitude | 307 |
| Country | United States |
#2 Bluffton
Town in Beaufort County, South Carolina, United States
| Population | 28,230 |
| Coordinates | 32.2371500, -80.8603900 |
| Altitude | 6 |
| Country | United States |
End: Bluffton (-80.86039, 32.23715)
Estimated Travel Time
Distance: 396 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 11m |
| 40 mph (64.37 km/h) | 06h 08m |
| 50 mph (80.47 km/h) | 04h 54m |
| 60 mph (96.56 km/h) | 04h 05m |
| 70 mph (112.65 km/h) | 03h 30m |
| 80 mph (129 km/h) | 03h 03m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $34.34 | $68.68 |
| Mid-grade | $4.43 | $38.40 | $76.80 |
| Premium | $4.78 | $41.43 | $82.85 |
| Diesel | $5.62 | $48.76 | $97.52 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in South Carolina · Apr 13, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.