How far is Gladstone, MO from St. Louis, MO?
The driving distance from Gladstone, MO to St. Louis, MO is about 256.1 miles (412.2 km), with a travel time of about 03h 54m by car.
- The straight-line flight distance is about 237.6 miles (382.3 km).
- For a round trip, plan for roughly 07h 49m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 54m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
The most populous city in the state of Missouri.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms
Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between Gladstone and St. Louis.
Turn-by-Turn Driving Directions
Step-by-step road directions between Gladstone and St. Louis.
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1
Start on North Garfield Avenue
126 m · 21 sec · North Garfield Avenue
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2
Turn right onto Northeast 61st Street
1843 ft · 1 min · Northeast 61st Street
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3
Turn right onto North Antioch Road
1.2 km · 2 min · North Antioch Road
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4
Turn left onto Northeast Chouteau Trafficway
1.7 mi · 3 min · Northeast Chouteau Trafficway
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5
Continue on Northeast Chouteau Parkway
1.6 mi · 3 min · Northeast Chouteau Parkway
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6
Continue on North Chouteau Trafficway
1.7 mi · 3 min · North Chouteau Trafficway
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7
Turn left onto East Front Street
1.2 mi · 2 min · East Front Street
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8
Take the ramp slight right toward I 435 South: Grandview
1353 ft · 33 sec
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9
Merge slight left onto Lamar Hunt Memorial Highway
4.4 mi · 5 min · Lamar Hunt Memorial Highway
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10
Keep slight right to continue on I 70, US 24 West, US 40: Saint Louis, Kansas City, Sports Complex
1500 ft · 23 sec
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11
Keep slight left to continue on I 70 East: Saint Louis
1.2 mi · 2 min
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12
Keep slight left to continue on I 70 East: Saint Louis
143 m · 12 sec
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13
Merge slight left onto George Brett Super Highway
2213 ft · 29 sec · George Brett Super Highway
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14
Continue on Truman/Eisenhower Presidential Highway
2.9 mi · 3 min · Truman/Eisenhower Presidential Highway
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15
Continue on Clifton J. Scott Memorial Highway
1.8 mi · 2 min · Clifton J. Scott Memorial Highway
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16
Continue on Truman/Eisenhower Presidential Highway
2.6 mi · 3 min · Truman/Eisenhower Presidential Highway
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17
Continue on Dwight D. Eisenhower Highway
52.5 mi · 57 min · Dwight D. Eisenhower Highway
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18
Continue on U.S. Submarine Veterans' Memorial Highway
32 mi · 34 min · U.S. Submarine Veterans' Memorial Highway
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19
Keep slight left to continue on U.S. Submarine Veterans' Memorial Highway
22.4 mi · 24 min · U.S. Submarine Veterans' Memorial Highway
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20
Continue on Dwight D. Eisenhower Highway
1.8 mi · 2 min · Dwight D. Eisenhower Highway
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21
Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway
1.6 mi · 2 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
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22
Continue on Sheriff Roger I. Wilson Memorial Highway
1.9 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
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23
Continue on Dwight D. Eisenhower Highway
81 mi · 1 hr 35 min · Dwight D. Eisenhower Highway
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24
Take the exit slight right toward I 64 East, US 40 East, US 61 South: Chesterfield
1567 ft · 33 sec
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25
Merge slight left onto Avenue of the Saints
27.7 mi · 34 min · Avenue of the Saints
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26
Continue on Daniel Boone Expressway
5.7 mi · 7 min · Daniel Boone Expressway
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27
Continue on Jack Buck Memorial Highway
5.8 mi · 7 min · Jack Buck Memorial Highway
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28
Take the exit slight right toward 14th Street
1115 ft · 34 sec
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29
Turn left onto South 14th Street
1715 ft · 42 sec · South 14th Street
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30
Turn right onto Market Street
956 ft · 25 sec · Market Street
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31
Arrive at your destination
0 m · 1 sec · Market Street
Car Route Details
A richer read on the saved driving route between Gladstone and St. Louis.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Dwight D. Eisenhower Highway
Continue on Dwight D. Eisenhower Highway
81 mi · 01h 35m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Showers And Thunderstorms leaving Gladstone and Showers And Thunderstorms Likely near St. Louis.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Gladstone to St. Louis?
The road trip is about 256.1 miles (412.2 km) and usually takes 03h 54m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Columbia is a useful midpoint, sitting about 127.1 miles from Gladstone and 129 miles from St. Louis.
How much longer is the road route than the straight-line distance?
The direct path is about 237.6 miles (382.3 km), while the road route adds roughly 18.5 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 9:10 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $34.09 one way or $68.18 round trip. Estimated CO2 is about 80.3 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms around Gladstone and Showers And Thunderstorms Likely near St. Louis.
Stop Ideas Near Columbia
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Columbia.
Jefferson City
Sedalia
Hermann
Flight Path Map
This map shows the direct air route between Gladstone and St. Louis. Straight-line distance: 237.56 mi (382.31 km).
#1 Gladstone
City in Missouri, USA
| Population | 27,677 |
| Coordinates | 39.2038900, -94.5546800 |
| Altitude | 287 |
| Country | United States |
#2 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
End: Market Street (-90.197859, 38.627348)
Estimated Travel Time
Distance: 412 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 32m |
| 40 mph (64.37 km/h) | 06h 24m |
| 50 mph (80.47 km/h) | 05h 07m |
| 60 mph (96.56 km/h) | 04h 16m |
| 70 mph (112.65 km/h) | 03h 39m |
| 80 mph (129 km/h) | 03h 11m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $34.09 | $68.18 |
| Mid-grade | $4.25 | $38.45 | $76.89 |
| Premium | $4.65 | $42.07 | $84.14 |
| Diesel | $5.30 | $47.95 | $95.90 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 24, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.