How far is Doniphan, MO from O'Fallon, MO?
The driving distance from Doniphan, MO to O'Fallon, MO is about 202.3 miles (325.6 km), with a travel time of about 03h 18m by car.
- The straight-line flight distance is about 151.4 miles (243.7 km).
- For a round trip, plan for roughly 06h 36m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 18m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in St.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms
Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Doniphan and O'Fallon.
Turn-by-Turn Driving Directions
Step-by-step road directions between Doniphan and O'Fallon.
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1
Start on Plum Street
52 m · 10 sec · Plum Street
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2
Turn right onto Walnut Street
1.1 km · 1 min · Walnut Street
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3
Turn right
18.3 mi · 27 min
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4
Turn left
30 m · 2 sec
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5
Take the ramp slight right
890 ft · 24 sec
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6
Merge slight left
10.5 mi · 11 min
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7
Take the exit slight right toward US 60 West, US 67 North: Springfield
113.3 mi · 2 hr 10 min
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8
Keep slight right
1750 ft · 27 sec
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9
Take the exit straight toward I 55 North: Saint Louis
1735 ft · 49 sec
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10
Merge slight left
20.5 mi · 22 min
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11
Continue on Rosa Parks Highway
1.3 mi · 2 min · Rosa Parks Highway
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12
Take the exit slight right toward I 270 West, I 255 East: Kansas City, Chicago
1279 ft · 27 sec
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13
Keep slight left to continue on I 270 West: Kansas City
118 m · 8 sec
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14
Continue on I 270 West
1.2 km · 1 min
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15
Merge slight left
18.1 mi · 23 min
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16
Take the exit slight right toward I 70: Kansas City, Saint Louis, Saint Louis Lambert International Airport
1 mi · 1 min
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17
Keep slight left to continue on I 70 West: Kansas City
645 ft · 11 sec
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18
Continue on I 70 West: Kansas City
1 km · 57 sec
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19
Merge slight left
13.6 mi · 17 min
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20
Take the exit slight right toward MO K: O'Fallon, Main Street
119 m · 8 sec
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21
Turn straight onto East Terra Lane
1.4 km · 2 min · East Terra Lane
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22
Turn right onto South Main Street
2830 ft · 1 min · South Main Street
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23
Turn right
8 m · 2 sec
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24
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Doniphan and O'Fallon.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
US 60 West
Take the exit slight right toward US 60 West, US 67 North: Springfield
113 mi · 02h 10m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Showers And Thunderstorms leaving Doniphan and Showers And Thunderstorms near O'Fallon.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Doniphan to O'Fallon?
The road trip is about 202.3 miles (325.6 km) and usually takes 03h 18m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Farmington is a useful midpoint, sitting about 100.8 miles from Doniphan and 101.4 miles from O'Fallon.
How much longer is the road route than the straight-line distance?
The direct path is about 151.4 miles (243.7 km), while the road route adds roughly 50.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 10:24 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $26.92 one way or $53.85 round trip. Estimated CO2 is about 63.5 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms around Doniphan and Showers And Thunderstorms near O'Fallon.
Stop Ideas Near Farmington
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Farmington.
Kirkwood
Gateway Transportation Center
Washington
Carbondale station
Flight Path Map
This map shows the direct air route between Doniphan and O'Fallon. Straight-line distance: 151.45 mi (243.73 km).
#1 Doniphan
City in Ripley County, Missouri, United States
| Population | 1,919 |
| Coordinates | 36.6208900, -90.8234600 |
| Altitude | 122 |
| Country | United States |
#2 O'Fallon
The most populous city in St.
| Population | 89,769 |
| Coordinates | 38.8106100, -90.6998500 |
| Altitude | 165 |
| Country | United States |
End: (-90.699849, 38.810674)
Estimated Travel Time
Distance: 326 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 44m |
| 40 mph (64.37 km/h) | 05h 03m |
| 50 mph (80.47 km/h) | 04h 02m |
| 60 mph (96.56 km/h) | 03h 22m |
| 70 mph (112.65 km/h) | 02h 53m |
| 80 mph (129 km/h) | 02h 31m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $26.92 | $53.85 |
| Mid-grade | $4.25 | $30.37 | $60.73 |
| Premium | $4.65 | $33.23 | $66.46 |
| Diesel | $5.30 | $37.87 | $75.74 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.