How far is De Kalb, MS from Tupelo, MS?
The driving distance from De Kalb, MS to Tupelo, MS is about 112.5 miles (181 km), with a travel time of about 01h 56m by car.
- The straight-line flight distance is about 103 miles (165.8 km).
- For a round trip, plan for roughly 03h 53m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 01h 56m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town of the United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny
Sunny
Driving Route Map
The map below follows the saved road route between De Kalb and Tupelo.
Turn-by-Turn Driving Directions
Step-by-step road directions between De Kalb and Tupelo.
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1
Start on Main Avenue
2979 ft · 55 sec · Main Avenue
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2
At the end of the road, turn left
28 m · 2 sec
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3
Turn right
19.5 mi · 29 min
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4
At the end of the road, turn left
18.3 mi · 21 min
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5
Keep slight left to continue on US Highway 45 Alternate
53 mi · 1 hr 4 min · US Highway 45 Alternate
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6
Continue on Martin Luther King Drive
18.1 mi · 21 min · Martin Luther King Drive
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7
Continue on Martin Luther King, Junior Drive
1.5 mi · 2 min · Martin Luther King, Junior Drive
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8
Take the exit slight right toward MS 6 East: Downtown Tupelo
2008 ft · 49 sec
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9
Keep slight left
52 m · 7 sec
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10
Turn left onto East Main Street
1.1 km · 2 min · East Main Street
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11
Turn right onto North Spring Street
70 m · 10 sec · North Spring Street
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12
Arrive at your destination
0 m · 1 sec · North Spring Street
Car Route Details
A richer read on the saved driving route between De Kalb and Tupelo.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
US Highway 45 Alternate
Keep slight left to continue on US Highway 45 Alternate
53 mi · 01h 04m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Partly Sunny leaving De Kalb and Sunny near Tupelo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from De Kalb to Tupelo?
The road trip is about 112.5 miles (181 km) and usually takes 01h 56m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Artesia is a useful midpoint, sitting about 56.2 miles from De Kalb and 56.3 miles from Tupelo.
How much longer is the road route than the straight-line distance?
The direct path is about 103 miles (165.8 km), while the road route adds roughly 9.5 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 2:36 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $15.03 one way or $30.07 round trip. Estimated CO2 is about 35.3 kg one way.
What should you check before leaving?
Before you leave, expect Partly Sunny around De Kalb and Sunny near Tupelo.
Stop Ideas Near Artesia
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Artesia.
Tuscaloosa
Union Station
Flight Path Map
This map shows the direct air route between De Kalb and Tupelo. Straight-line distance: 103.02 mi (165.8 km).
#1 De Kalb
Town in Mississippi, United States
| Population | 1,005 |
| Coordinates | 32.7676300, -88.6508800 |
| Altitude | 141 |
| Country | United States |
#2 Tupelo
City in and county seat of Lee County, Mississippi, United States
| Population | 38,303 |
| Coordinates | 34.2580700, -88.7046400 |
| Altitude | 85 |
| Country | United States |
End: North Spring Street (-88.704455, 34.258074)
Estimated Travel Time
Distance: 181 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 03h 44m |
| 40 mph (64.37 km/h) | 02h 48m |
| 50 mph (80.47 km/h) | 02h 14m |
| 60 mph (96.56 km/h) | 01h 52m |
| 70 mph (112.65 km/h) | 01h 36m |
| 80 mph (129 km/h) | 01h 24m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $15.03 | $30.07 |
| Mid-grade | $4.26 | $16.91 | $33.82 |
| Premium | $4.63 | $18.36 | $36.72 |
| Diesel | $5.42 | $21.50 | $43.00 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.