How far is De Kalb, MS from Biloxi, MS?
The driving distance from De Kalb, MS to Biloxi, MS is about 199.8 miles (321.5 km), with a travel time of about 03h 12m by car.
- The straight-line flight distance is about 164.4 miles (264.6 km).
- For a round trip, plan for roughly 06h 25m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 12m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Mississippi, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny
Partly Sunny
Driving Route Map
The map below follows the saved road route between De Kalb and Biloxi.
Turn-by-Turn Driving Directions
Step-by-step road directions between De Kalb and Biloxi.
-
1
Start on Main Avenue
727 ft · 12 sec · Main Avenue
-
2
Turn slight left onto Church Street
28.6 mi · 43 min · Church Street
-
3
Turn straight onto Dale Drive
1202 ft · 24 sec · Dale Drive
-
4
Turn left
1.2 km · 1 min
-
5
Turn right
557 ft · 9 sec
-
6
Keep slight left to continue on South I 59, West I 20: Jackson
4.1 mi · 5 min
-
7
Continue straight
1.8 mi · 2 min
-
8
Keep slight left to continue on I 59 South: Laurel, New Orleans
88.7 mi · 1 hr 36 min
-
9
Take the exit slight right toward US 98 East: Lucedale, Mobile
3.2 mi · 4 min
-
10
Take the exit slight right toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast
1558 ft · 44 sec
-
11
Keep slight left to continue on Multi Purpose Center, Hattiesburg
833 ft · 28 sec
-
12
Turn right
41.9 mi · 49 min
-
13
Take the exit slight right toward MS 67 South: D'Iberville, Biloxi
1.2 km · 1 min
-
14
Continue on Biloxi-D'Iberville Scenic Expressway
20.5 mi · 24 min · Biloxi-D'Iberville Scenic Expressway
-
15
Continue straight
3.2 mi · 4 min
-
16
Take the exit slight right toward Division Street
1852 ft · 47 sec
-
17
Turn left onto Division Street
3090 ft · 2 min · Division Street
-
18
Turn right onto Main Street
2572 ft · 1 min · Main Street
-
19
Turn left onto Howard Avenue
28 m · 3 sec · Howard Avenue
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20
Arrive at your destination
0 m · 1 sec · Howard Avenue
Car Route Details
A richer read on the saved driving route between De Kalb and Biloxi.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 59 South
Keep slight left to continue on I 59 South: Laurel, New Orleans
88.7 mi · 01h 36m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Partly Sunny leaving De Kalb and Partly Sunny near Biloxi.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from De Kalb to Biloxi?
The road trip is about 199.8 miles (321.5 km) and usually takes 03h 12m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Ellisville is a useful midpoint, sitting about 98.1 miles from De Kalb and 101.8 miles from Biloxi.
How much longer is the road route than the straight-line distance?
The direct path is about 164.4 miles (264.6 km), while the road route adds roughly 35.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 10:34 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $26.70 one way or $53.40 round trip. Estimated CO2 is about 62.7 kg one way.
What should you check before leaving?
Before you leave, expect Partly Sunny around De Kalb and Partly Sunny near Biloxi.
Stop Ideas Near Ellisville
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Ellisville.
Laurel station
Hattiesburg, MS
Hattiesburg station
Union Station
Flight Path Map
This map shows the direct air route between De Kalb and Biloxi. Straight-line distance: 164.44 mi (264.64 km).
#1 De Kalb
Town in Mississippi, United States
| Population | 1,005 |
| Coordinates | 32.7676300, -88.6508800 |
| Altitude | 141 |
| Country | United States |
#2 Biloxi
The most populous city in Harrison County, Mississippi.
| Population | 46,127 |
| Coordinates | 30.3960300, -88.8853100 |
| Altitude | 6 |
| Country | United States |
End: Howard Avenue (-88.885301, 30.396075)
Estimated Travel Time
Distance: 322 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 39m |
| 40 mph (64.37 km/h) | 04h 59m |
| 50 mph (80.47 km/h) | 03h 59m |
| 60 mph (96.56 km/h) | 03h 19m |
| 70 mph (112.65 km/h) | 02h 51m |
| 80 mph (129 km/h) | 02h 29m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $26.70 | $53.40 |
| Mid-grade | $4.26 | $30.03 | $60.05 |
| Premium | $4.63 | $32.61 | $65.21 |
| Diesel | $5.42 | $38.18 | $76.35 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.