How far is Tupelo, MS from De Kalb, MS?
The driving distance from Tupelo, MS to De Kalb, MS is about 112 miles (180.2 km), with a travel time of about 02h 20m by car.
- The straight-line flight distance is about 103 miles (165.8 km).
- For a round trip, plan for roughly 04h 41m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 20m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town of the United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny
Driving Route Map
The map below follows the saved road route between Tupelo and De Kalb.
Turn-by-Turn Driving Directions
Step-by-step road directions between Tupelo and De Kalb.
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1
Start on North Spring Street
21 m · 5 sec · North Spring Street
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2
Turn right onto Court Street
97 m · 16 sec · Court Street
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3
Turn right onto North Front Street
87 m · 15 sec · North Front Street
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4
Turn left onto East Main Street
2407 ft · 1 min · East Main Street
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5
Take the ramp straight
2248 ft · 56 sec
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6
Merge slight left onto Martin Luther King Drive
1.6 km · 1 min · Martin Luther King Drive
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7
Continue on Martin Luther King, Junior Drive
2.3 mi · 3 min · Martin Luther King, Junior Drive
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8
Continue on Martin Luther King Drive
7.7 mi · 9 min · Martin Luther King Drive
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9
Continue straight
1.4 mi · 2 min
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10
Continue straight
2.2 mi · 2 min
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11
Continue straight
1.5 mi · 2 min
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12
Continue straight
1.1 km · 49 sec
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13
Continue straight
1.4 mi · 2 min
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14
Continue on US Highway 45 Alternate
54.7 mi · 1 hr 6 min · US Highway 45 Alternate
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15
Continue on US Highway 45 Aiternate
18 mi · 21 min · US Highway 45 Aiternate
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16
Turn right
4.3 mi · 6 min
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17
Keep slight left
15.2 mi · 23 min
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18
At the end of the road, turn left
28 m · 3 sec
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19
Turn right onto Main Avenue
2979 ft · 50 sec · Main Avenue
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20
Arrive at your destination
0 m · 1 sec · Main Avenue
Car Route Details
A richer read on the saved driving route between Tupelo and De Kalb.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
US Highway 45 Alternate
Continue on US Highway 45 Alternate
54.7 mi · 01h 06m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Sunny leaving Tupelo and Partly Sunny near De Kalb.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Tupelo to De Kalb?
The road trip is about 112 miles (180.2 km) and usually takes 02h 20m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Artesia is a useful midpoint, sitting about 56.1 miles from Tupelo and 55.9 miles from De Kalb.
How much longer is the road route than the straight-line distance?
The direct path is about 103 miles (165.8 km), while the road route adds roughly 9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 1:48 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $14.96 one way or $29.92 round trip. Estimated CO2 is about 35.1 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Tupelo and Partly Sunny near De Kalb.
Stop Ideas Near Artesia
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Artesia.
Tuscaloosa
Union Station
Flight Path Map
This map shows the direct air route between Tupelo and De Kalb. Straight-line distance: 103.02 mi (165.8 km).
#1 Tupelo
City in and county seat of Lee County, Mississippi, United States
| Population | 38,303 |
| Coordinates | 34.2580700, -88.7046400 |
| Altitude | 85 |
| Country | United States |
#2 De Kalb
Town in Mississippi, United States
| Population | 1,005 |
| Coordinates | 32.7676300, -88.6508800 |
| Altitude | 141 |
| Country | United States |
End: De Kalb (-88.65088, 32.76763)
Estimated Travel Time
Distance: 180 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 03h 43m |
| 40 mph (64.37 km/h) | 02h 47m |
| 50 mph (80.47 km/h) | 02h 14m |
| 60 mph (96.56 km/h) | 01h 51m |
| 70 mph (112.65 km/h) | 01h 35m |
| 80 mph (129 km/h) | 01h 23m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $14.96 | $29.92 |
| Mid-grade | $4.26 | $16.82 | $33.65 |
| Premium | $4.63 | $18.27 | $36.54 |
| Diesel | $5.42 | $21.39 | $42.78 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.