How far is Cayce, SC from Greenville, SC?
The driving distance from Cayce, SC to Greenville, SC is about 105.3 miles (169.5 km), with a travel time of about 01h 35m by car.
- The straight-line flight distance is about 97.1 miles (156.2 km).
- For a round trip, plan for roughly 03h 11m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM EDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 01h 35m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census-designated place in Laurens County, South Carolina
Route Weather Snapshot
Check the forecast at both ends before you head out.
Slight Chance Showers And Thunderstorms
Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between Cayce and Greenville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Cayce and Greenville.
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1
Start on Middleton Street
50 m · 8 sec · Middleton Street
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2
Turn right onto Glenn Street
2479 ft · 2 min · Glenn Street
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3
Turn left onto Airport Boulevard
1.6 km · 2 min · Airport Boulevard
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4
Take the ramp right toward I 26 West: Spartanburg
1059 ft · 26 sec
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5
Merge slight left
61 mi · 1 hr 7 min
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6
Keep slight left to continue on I 385 North: Laurens, Greenville
29.6 mi · 32 min
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7
Keep slight left to continue on Golden Strip Freeway
12.4 mi · 15 min · Golden Strip Freeway
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8
Continue on East North Street
1270 ft · 19 sec · East North Street
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9
Continue on Beattie Place
1231 ft · 27 sec · Beattie Place
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10
Turn right onto North Church Street
18 m · 2 sec · North Church Street
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11
Arrive at your destination
0 m · 1 sec · North Church Street
Car Route Details
A richer read on the saved driving route between Cayce and Greenville.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 26 West
Merge slight left
61 mi · 01h 07m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Slight Chance Showers And Thunderstorms leaving Cayce and Showers And Thunderstorms Likely near Greenville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Cayce to Greenville?
The road trip is about 105.3 miles (169.5 km) and usually takes 01h 35m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Joanna is a useful midpoint, sitting about 52.6 miles from Cayce and 52.7 miles from Greenville.
How much longer is the road route than the straight-line distance?
The direct path is about 97.1 miles (156.2 km), while the road route adds roughly 8.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM EDT. If you want a more comfortable same-day return, try to leave by 3:18 PM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $14.73 one way or $29.47 round trip. Estimated CO2 is about 33.1 kg one way.
What should you check before leaving?
Before you leave, expect Slight Chance Showers And Thunderstorms around Cayce and Showers And Thunderstorms Likely near Greenville.
Stop Ideas Near Joanna
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Joanna.
Spartanburg
Greenville
Columbia
Clemson
Flight Path Map
This map shows the direct air route between Cayce and Greenville. Straight-line distance: 97.04 mi (156.17 km).
#1 Cayce
City in Lexington and Richland counties in South Carolina, United States
| Population | 13,994 |
| Coordinates | 33.9657100, -81.0739800 |
| Altitude | 73 |
| Country | United States |
#2 Greenville
The most populous city in Greenville County, South Carolina.
| Population | 72,227 |
| Coordinates | 34.8526200, -82.3940100 |
| Altitude | 307 |
| Country | United States |
End: North Church Street (-82.394165, 34.852668)
Estimated Travel Time
Distance: 169 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 03h 30m |
| 40 mph (64.37 km/h) | 02h 37m |
| 50 mph (80.47 km/h) | 02h 06m |
| 60 mph (96.56 km/h) | 01h 45m |
| 70 mph (112.65 km/h) | 01h 30m |
| 80 mph (129 km/h) | 01h 18m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $14.73 | $29.47 |
| Mid-grade | $4.43 | $16.48 | $32.95 |
| Premium | $4.78 | $17.77 | $35.55 |
| Diesel | $5.62 | $20.92 | $41.84 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in South Carolina · Apr 30, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.