How far is Cape Girardeau, MO from Webb City, MO?
The driving distance from Cape Girardeau, MO to Webb City, MO is about 338.7 miles (545.1 km), with a travel time of about 06h 33m by car.
- The straight-line flight distance is about 272.2 miles (438.1 km).
- For a round trip, plan for roughly 13h 06m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 33m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Howell County, Missouri, USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms
Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Cape Girardeau and Webb City.
Turn-by-Turn Driving Directions
Step-by-step road directions between Cape Girardeau and Webb City.
-
1
Start on Broadway Street
2497 ft · 56 sec · Broadway Street
-
2
Turn left onto North Sprigg Street
1.2 km · 2 min · North Sprigg Street
-
3
Turn right onto Shawnee Parkway
1.6 mi · 3 min · Shawnee Parkway
-
4
Turn left onto South Kingshighway
1.9 mi · 3 min · South Kingshighway
-
5
Keep slight left to continue on I 55 South, US 61 South: Sikeston
27.2 mi · 29 min
-
6
Take the exit slight right toward US 60 West: Dexter, Poplar Bluff
2865 ft · 1 min
-
7
Merge slight left
45.4 mi · 52 min
-
8
Keep slight left
5.5 mi · 6 min
-
9
Take the exit slight right toward US 60 West, US 67 North: Springfield, Saint Louis
4.5 mi · 6 min
-
10
Take the exit slight right
186.3 mi · 3 hr 39 min
-
11
Keep slight left to continue on I 44 West: Joplin
1.3 km · 2 min
-
12
Merge slight left onto Captain Aaron J Eidem Memorial Highway
56.3 mi · 1 hr · Captain Aaron J Eidem Memorial Highway
-
13
Take the exit slight right toward I 49 South, US 71 South, MO 249 North: Neosho, Fort Smith
1447 ft · 25 sec
-
14
Keep slight right to continue on MO 249 North
1015 ft · 22 sec
-
15
Merge slight left onto Governor Warren E Hearnes Memorial Highway
5 mi · 5 min · Governor Warren E Hearnes Memorial Highway
-
16
Take the exit slight left toward I 49 Business, MO 171 North: Webb City
3027 ft · 38 sec
-
17
Merge slight right onto I 49 Business, MO 171 North: Webb City
1 km · 47 sec
-
18
Enter the roundabout and take exit 2 toward East MacArthur Drive
72 m · 3 sec · East MacArthur Drive
-
19
Exit the roundabout onto East MacArthur Drive
1434 ft · 27 sec · East MacArthur Drive
-
20
Turn right onto South Main Street
1920 ft · 39 sec · South Main Street
-
21
Arrive at your destination
0 m · 1 sec · North Main Street
Car Route Details
A richer read on the saved driving route between Cape Girardeau and Webb City.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
US 60 West
Take the exit slight right
186 mi · 03h 39m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Showers And Thunderstorms leaving Cape Girardeau and Showers And Thunderstorms near Webb City.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Cape Girardeau to Webb City?
The road trip is about 338.7 miles (545.1 km) and usually takes 06h 33m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Mountain View is a useful midpoint, sitting about 169.1 miles from Cape Girardeau and 169.6 miles from Webb City.
How much longer is the road route than the straight-line distance?
The direct path is about 272.2 miles (438.1 km), while the road route adds roughly 66.5 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $45.06 one way or $90.13 round trip. Estimated CO2 is about 106.2 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms around Cape Girardeau and Showers And Thunderstorms near Webb City.
Flight Path Map
This map shows the direct air route between Cape Girardeau and Webb City. Straight-line distance: 272.24 mi (438.12 km).
#1 Cape Girardeau
The second-largest city in Cape Girardeau County, Missouri.
| Population | 41,588 |
| Coordinates | 37.3058800, -89.5181500 |
| Altitude | 108 |
| Country | United States |
#2 Webb City
City in Missouri
| Population | 12,134 |
| Coordinates | 37.1464500, -94.4630000 |
| Altitude | 305 |
| Country | United States |
End: Webb City (-94.463, 37.14645)
Estimated Travel Time
Distance: 545 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 17m |
| 40 mph (64.37 km/h) | 08h 28m |
| 50 mph (80.47 km/h) | 06h 46m |
| 60 mph (96.56 km/h) | 05h 38m |
| 70 mph (112.65 km/h) | 04h 50m |
| 80 mph (129 km/h) | 04h 13m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $45.06 | $90.13 |
| Mid-grade | $4.25 | $50.82 | $101.65 |
| Premium | $4.65 | $55.62 | $111.23 |
| Diesel | $5.30 | $63.38 | $126.77 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.