How far is Cape Girardeau, MO from Berkeley, MO?
The driving distance from Cape Girardeau, MO to Berkeley, MO is about 123.8 miles (199.2 km), with a travel time of about 02h 29m by car.
- The straight-line flight distance is about 109.4 miles (176.1 km).
- For a round trip, plan for roughly 04h 58m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 29m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Sainte Genevieve County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Cloudy
Scattered Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Cape Girardeau and Berkeley.
Turn-by-Turn Driving Directions
Step-by-step road directions between Cape Girardeau and Berkeley.
-
1
Start on Broadway Street
2 mi · 4 min · Broadway Street
-
2
Turn right onto North Kingshighway
3.6 mi · 6 min · North Kingshighway
-
3
Take the ramp slight right toward I 55 North: Saint Louis
1606 ft · 39 sec
-
4
Merge slight left
95.1 mi · 1 hr 42 min
-
5
Continue on Rosa Parks Highway
4.3 mi · 5 min · Rosa Parks Highway
-
6
Take the exit slight right toward Reavis Barracks Road
742 ft · 24 sec
-
7
Turn left onto Reavis Barracks Road
1.2 km · 2 min · Reavis Barracks Road
-
8
Continue on Mackenzie Road
2623 ft · 1 min · Mackenzie Road
-
9
Turn left onto Reavis Road
2639 ft · 1 min · Reavis Road
-
10
Turn right onto Tesson Ferry Road
2511 ft · 58 sec · Tesson Ferry Road
-
11
Continue on South Rock Hill Road
3232 ft · 1 min · South Rock Hill Road
-
12
Turn slight right
43 m · 4 sec
-
13
Turn straight onto Laclede Station Road
3.5 mi · 6 min · Laclede Station Road
-
14
Continue on South Hanley Road
1.6 mi · 3 min · South Hanley Road
-
15
Turn slight right onto Eager Road
3052 ft · 1 min · Eager Road
-
16
Take the ramp slight right toward I 170 North
2323 ft · 34 sec
-
17
Merge slight right onto Inner Belt Expressway
8.5 mi · 11 min · Inner Belt Expressway
-
18
Take the exit slight right toward Airport Road
950 ft · 20 sec
-
19
Turn right onto Airport Road
1684 ft · 41 sec · Airport Road
-
20
Turn left onto Evergreen Boulevard
1653 ft · 1 min · Evergreen Boulevard
-
21
Arrive at your destination
0 m · 1 sec · Evergreen Boulevard
Car Route Details
A richer read on the saved driving route between Cape Girardeau and Berkeley.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 55 North
Merge slight left
95.1 mi · 01h 42m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Mostly Cloudy leaving Cape Girardeau and Scattered Showers And Thunderstorms near Berkeley.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Cape Girardeau to Berkeley?
The road trip is about 123.8 miles (199.2 km) and usually takes 02h 29m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Bloomsdale is a useful midpoint, sitting about 61.9 miles from Cape Girardeau and 61.9 miles from Berkeley.
How much longer is the road route than the straight-line distance?
The direct path is about 109.4 miles (176.1 km), while the road route adds roughly 14.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 1:32 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $16.48 one way or $32.96 round trip. Estimated CO2 is about 38.8 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Cloudy around Cape Girardeau and Scattered Showers And Thunderstorms near Berkeley.
Stop Ideas Near Bloomsdale
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Bloomsdale.
Kirkwood
Gateway Transportation Center
Du Quoin
Carbondale station
Flight Path Map
This map shows the direct air route between Cape Girardeau and Berkeley. Straight-line distance: 109.44 mi (176.12 km).
#1 Cape Girardeau
The second-largest city in Cape Girardeau County, Missouri.
| Population | 41,588 |
| Coordinates | 37.3058800, -89.5181500 |
| Altitude | 108 |
| Country | United States |
#2 Berkeley
Suburb of St.
| Population | 8,892 |
| Coordinates | 38.7545000, -90.3312300 |
| Altitude | 164 |
| Country | United States |
End: Berkeley (-90.33123, 38.7545)
Estimated Travel Time
Distance: 199 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 04h 07m |
| 40 mph (64.37 km/h) | 03h 05m |
| 50 mph (80.47 km/h) | 02h 28m |
| 60 mph (96.56 km/h) | 02h 03m |
| 70 mph (112.65 km/h) | 01h 46m |
| 80 mph (129 km/h) | 01h 32m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $16.48 | $32.96 |
| Mid-grade | $4.25 | $18.59 | $37.17 |
| Premium | $4.65 | $20.34 | $40.68 |
| Diesel | $5.30 | $23.18 | $46.36 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 15, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.