How far is Cape Coral, FL from San Antonio, FL?
The driving distance from Cape Coral, FL to San Antonio, FL is about 156.3 miles (251.5 km), with a travel time of about 03h 05m by car.
- The straight-line flight distance is about 124.1 miles (199.8 km).
- For a round trip, plan for roughly 06h 10m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 05m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census-designated place in Sarasota County, Florida
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Cape Coral and San Antonio.
Turn-by-Turn Driving Directions
Step-by-step road directions between Cape Coral and San Antonio.
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1
Start on the route
29 m · 7 sec
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2
Turn right onto Cape Coral Parkway East
38 m · 7 sec · Cape Coral Parkway East
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3
Turn right onto Vincennes Boulevard
109 m · 13 sec · Vincennes Boulevard
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4
Enter the roundabout and take exit 2 toward Vincennes Boulevard
19 m · 2 sec · Vincennes Boulevard
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5
Exit the roundabout onto Vincennes Boulevard
2436 ft · 1 min · Vincennes Boulevard
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6
Turn right onto Coronado Parkway
1 km · 2 min · Coronado Parkway
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7
Turn left onto Del Prado Boulevard South
5.2 mi · 11 min · Del Prado Boulevard South
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8
Continue on Del Prado Boulevard North
6.5 mi · 11 min · Del Prado Boulevard North
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9
Turn left onto North Tamiami Trail
10.4 mi · 13 min · North Tamiami Trail
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10
Turn right onto Tuckers Grade
1.1 mi · 2 min · Tuckers Grade
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11
Take the ramp slight left toward I 75 North: Tampa
2299 ft · 56 sec
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12
Merge slight left
127.5 mi · 2 hr 18 min
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13
Take the exit slight right toward FL 52: Dade City, San Antonio
1846 ft · 45 sec
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14
Keep slight right to continue on FL 52 East
64 m · 6 sec
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15
Turn straight onto State Road 52
1.2 mi · 2 min · State Road 52
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16
Turn slight left
103 m · 14 sec
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17
Continue on Old State Road 52
1.9 mi · 3 min · Old State Road 52
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18
Turn left onto Curley Street
1552 ft · 50 sec · Curley Street
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19
Turn left onto Pennsylvania Avenue
19 m · 3 sec · Pennsylvania Avenue
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20
Arrive at your destination
0 m · 1 sec · Pennsylvania Avenue
Car Route Details
A richer read on the saved driving route between Cape Coral and San Antonio.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 75 North
Merge slight left
128 mi · 02h 18m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Cape Coral and Sunny near San Antonio.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Cape Coral to San Antonio?
The road trip is about 156.3 miles (251.5 km) and usually takes 03h 05m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
The Meadows is a useful midpoint, sitting about 78.3 miles from Cape Coral and 78 miles from San Antonio.
How much longer is the road route than the straight-line distance?
The direct path is about 124.1 miles (199.8 km), while the road route adds roughly 32.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 10:50 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $22.90 one way or $45.79 round trip. Estimated CO2 is about 49.1 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Cape Coral and Sunny near San Antonio.
Stop Ideas Near The Meadows
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to The Meadows.
Sarasota, Florida
Bradenton, Florida
Port Charlotte, Florida
St Petersburg-Pinellas Park-Clearwater, Florida
Flight Path Map
This map shows the direct air route between Cape Coral and San Antonio. Straight-line distance: 124.13 mi (199.77 km).
#1 Cape Coral
The second most populous city in Lee County, Florida.
| Population | 200,972 |
| Coordinates | 26.5628500, -81.9495300 |
| Altitude | 1 |
| Country | United States |
#2 San Antonio
City in Pasco County, Florida, USA
| Population | 1,506 |
| Coordinates | 28.3361100, -82.2745300 |
| Altitude | 51 |
| Country | United States |
End: San Antonio (-82.27453, 28.33611)
Estimated Travel Time
Distance: 252 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 12m |
| 40 mph (64.37 km/h) | 03h 54m |
| 50 mph (80.47 km/h) | 03h 07m |
| 60 mph (96.56 km/h) | 02h 36m |
| 70 mph (112.65 km/h) | 02h 13m |
| 80 mph (129 km/h) | 01h 56m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $22.90 | $45.79 |
| Mid-grade | $4.60 | $25.37 | $50.74 |
| Premium | $4.90 | $27.03 | $54.05 |
| Diesel | $4.35 | $24.01 | $48.02 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.