How far is Cameron, MO from Cape Girardeau, MO?
The driving distance from Cameron, MO to Cape Girardeau, MO is about 370.8 miles (596.7 km), with a travel time of about 05h 57m by car.
- The straight-line flight distance is about 305.7 miles (491.9 km).
- For a round trip, plan for roughly 11h 55m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 57m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
This departure sits inside the recommended comfort window for the route.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Missouri
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms Likely
Sunny
Driving Route Map
The map below follows the saved road route between Cameron and Cape Girardeau.
Turn-by-Turn Driving Directions
Step-by-step road directions between Cameron and Cape Girardeau.
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1
Start on West 2nd Street
12 m · 4 sec · West 2nd Street
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2
Turn right onto North Pine Street
758 ft · 35 sec · North Pine Street
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3
Turn right onto West 4th Street
1489 ft · 48 sec · West 4th Street
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4
Turn left onto North Walnut Street
1.2 km · 2 min · North Walnut Street
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5
Take the ramp slight right toward US 36 East: Hamilton
1165 ft · 18 sec
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6
Merge slight left
149.3 mi · 2 hr 53 min
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7
Continue on V.F.W. Memorial Highway
5.8 mi · 7 min · V.F.W. Memorial Highway
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8
Take the exit slight right toward Veterans Road
1167 ft · 30 sec
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9
Turn right onto Veterans Road
2.1 mi · 4 min · Veterans Road
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10
At the end of the road, turn left onto County Road 422
85 m · 7 sec · County Road 422
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11
Continue on Paris Gravel Road
2539 ft · 1 min · Paris Gravel Road
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12
Take the ramp right
37 m · 3 sec
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13
Merge slight left onto Avenue of the Saints
98.7 mi · 1 hr 58 min · Avenue of the Saints
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14
Take the exit slight right toward I 270: Chicago, Memphis
1829 ft · 39 sec
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15
Keep slight right to continue on I 270 South: Memphis
1691 ft · 31 sec
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16
Merge slight left
11.5 mi · 14 min
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17
Take the exit slight right toward I 55, US 61, US 67: Saint Louis, Memphis, Lemay Ferry Road
1911 ft · 27 sec
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18
Keep slight right to continue on I 55 South: Memphis
2031 ft · 44 sec
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19
Merge slight left onto Rosa Parks Highway
1.5 mi · 2 min · Rosa Parks Highway
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20
Continue on Officer Thomas G. Smith, Jr. Memorial Highway
1.8 mi · 2 min · Officer Thomas G. Smith, Jr. Memorial Highway
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21
Continue on Police Officer Steven Jarvis Memorial Highway
93.1 mi · 1 hr 40 min · Police Officer Steven Jarvis Memorial Highway
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22
Take the exit slight right toward US 61, MO 34, I 55 Business: Cape Girardeau, Jackson
814 ft · 17 sec
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23
Keep slight left to continue on I 55 Business, US 61 South, MO 34 East: Cape Girardeau
1354 ft · 29 sec
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24
Continue on North Kingshighway
3.6 mi · 6 min · North Kingshighway
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25
Turn left onto Broadway Street
2 mi · 4 min · Broadway Street
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26
Arrive at your destination
0 m · 1 sec · Broadway Street
Car Route Details
A richer read on the saved driving route between Cameron and Cape Girardeau.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
US 36 East
Merge slight left
149 mi · 02h 53m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Showers And Thunderstorms Likely leaving Cameron and Sunny near Cape Girardeau.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Cameron to Cape Girardeau?
The road trip is about 370.8 miles (596.7 km) and usually takes 05h 57m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Bowling Green is a useful midpoint, sitting about 186.6 miles from Cameron and 184.2 miles from Cape Girardeau.
How much longer is the road route than the straight-line distance?
The direct path is about 305.7 miles (491.9 km), while the road route adds roughly 65.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 5:04 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $49.32 one way or $98.65 round trip. Estimated CO2 is about 116.2 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms Likely around Cameron and Sunny near Cape Girardeau.
Stop Ideas Near Bowling Green
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Bowling Green.
Quincy
Hermann
Washington
Alton
Flight Path Map
This map shows the direct air route between Cameron and Cape Girardeau. Straight-line distance: 305.66 mi (491.91 km).
#1 Cameron
City in Missouri, USA
| Population | 8,136 |
| Coordinates | 39.7402800, -94.2410600 |
| Altitude | 315 |
| Country | United States |
#2 Cape Girardeau
The second-largest city in Cape Girardeau County, Missouri.
| Population | 41,588 |
| Coordinates | 37.3058800, -89.5181500 |
| Altitude | 108 |
| Country | United States |
End: Broadway Street (-89.518146, 37.305904)
Estimated Travel Time
Distance: 597 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 12h 21m |
| 40 mph (64.37 km/h) | 09h 16m |
| 50 mph (80.47 km/h) | 07h 24m |
| 60 mph (96.56 km/h) | 06h 10m |
| 70 mph (112.65 km/h) | 05h 17m |
| 80 mph (129 km/h) | 04h 37m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $49.32 | $98.65 |
| Mid-grade | $4.25 | $55.63 | $111.26 |
| Premium | $4.65 | $60.87 | $121.75 |
| Diesel | $5.30 | $69.38 | $138.75 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.