How far is Cameron, MO from Saint Charles, MO?
The driving distance from Cameron, MO to Saint Charles, MO is about 253 miles (407.2 km), with a travel time of about 04h 01m by car.
- The straight-line flight distance is about 211.7 miles (340.7 km).
- For a round trip, plan for roughly 08h 02m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 01m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
This departure sits inside the recommended comfort window for the route.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Cooper County, Missouri, USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms Likely
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Cameron and Saint Charles.
Turn-by-Turn Driving Directions
Step-by-step road directions between Cameron and Saint Charles.
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1
Start on West 2nd Street
1451 ft · 1 min · West 2nd Street
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2
At the end of the road, turn right onto North Walnut Street
13.1 mi · 17 min · North Walnut Street
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3
Enter the roundabout and take exit 3 toward the route
67 m · 4 sec
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4
Exit the roundabout
10.5 mi · 14 min
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5
Turn right onto Main Street
45.2 mi · 1 hr 2 min · Main Street
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6
Take the exit left toward I 70 East, US 40 East: Columbia
954 ft · 23 sec
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7
Merge slight left onto Dwight D. Eisenhower Highway
19.9 mi · 21 min · Dwight D. Eisenhower Highway
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8
Continue on U.S. Submarine Veterans' Memorial Highway
32 mi · 34 min · U.S. Submarine Veterans' Memorial Highway
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9
Keep slight left to continue on U.S. Submarine Veterans' Memorial Highway
22.4 mi · 24 min · U.S. Submarine Veterans' Memorial Highway
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10
Continue on Dwight D. Eisenhower Highway
1.8 mi · 2 min · Dwight D. Eisenhower Highway
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11
Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway
1.6 mi · 2 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
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12
Continue on Sheriff Roger I. Wilson Memorial Highway
1.9 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
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13
Continue on Dwight D. Eisenhower Highway
99 mi · 1 hr 57 min · Dwight D. Eisenhower Highway
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14
Take the exit slight right toward I 70 Business, MO 94: First Capitol Drive, Lewis and Clark Trail
653 ft · 14 sec
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15
Keep slight left to continue on I 70 Business, MO 94 East: First Capitol Drive, Lindenwood University, SSM Health Saint Joseph Hospital
596 ft · 15 sec
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16
Turn straight onto First Capitol Drive
1.5 km · 2 min · First Capitol Drive
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17
Turn slight right onto MO 94
1.4 km · 2 min
-
18
Turn left onto South Second Street
1551 ft · 57 sec · South Second Street
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19
Arrive at your destination
0 m · 1 sec · North Second Street
Car Route Details
A richer read on the saved driving route between Cameron and Saint Charles.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Dwight D. Eisenhower Highway
Continue on Dwight D. Eisenhower Highway
99 mi · 01h 57m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Showers And Thunderstorms Likely leaving Cameron and Mostly Sunny near Saint Charles.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Cameron to Saint Charles?
The road trip is about 253 miles (407.2 km) and usually takes 04h 01m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Boonville is a useful midpoint, sitting about 124.9 miles from Cameron and 128.1 miles from Saint Charles.
How much longer is the road route than the straight-line distance?
The direct path is about 211.7 miles (340.7 km), while the road route adds roughly 41.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:58 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $33.68 one way or $67.35 round trip. Estimated CO2 is about 79.4 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms Likely around Cameron and Mostly Sunny near Saint Charles.
Stop Ideas Near Boonville
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Boonville.
Sedalia
Jefferson City
Warrensburg
Hermann
Flight Path Map
This map shows the direct air route between Cameron and Saint Charles. Straight-line distance: 211.69 mi (340.68 km).
#1 Cameron
City in Missouri, USA
| Population | 8,136 |
| Coordinates | 39.7402800, -94.2410600 |
| Altitude | 315 |
| Country | United States |
#2 Saint Charles
A city in St.
| Population | 71,761 |
| Coordinates | 38.7839400, -90.4812300 |
| Altitude | 147 |
| Country | United States |
End: North Second Street (-90.481269, 38.783952)
Estimated Travel Time
Distance: 407 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 25m |
| 40 mph (64.37 km/h) | 06h 19m |
| 50 mph (80.47 km/h) | 05h 03m |
| 60 mph (96.56 km/h) | 04h 12m |
| 70 mph (112.65 km/h) | 03h 36m |
| 80 mph (129 km/h) | 03h 09m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $33.68 | $67.35 |
| Mid-grade | $4.25 | $37.98 | $75.96 |
| Premium | $4.65 | $41.56 | $83.12 |
| Diesel | $5.30 | $47.36 | $94.73 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.