How far is Apalachicola, FL from Port Saint Lucie, FL?
The driving distance from Apalachicola, FL to Port Saint Lucie, FL is about 412.7 miles (664.2 km), with a travel time of about 06h 52m by car.
- The straight-line flight distance is about 327.7 miles (527.4 km).
- For a round trip, plan for roughly 13h 45m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 52m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Florida, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms
Sunny
Driving Route Map
The map below follows the saved road route between Apalachicola and Port Saint Lucie.
Turn-by-Turn Driving Directions
Step-by-step road directions between Apalachicola and Port Saint Lucie.
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1
Start on 5th Street
563 ft · 30 sec · 5th Street
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2
Turn left onto Avenue C
139 m · 24 sec · Avenue C
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3
Turn right
42.9 mi · 1 hr 4 min
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4
Continue on Sopchoppy Highway
6.6 mi · 10 min · Sopchoppy Highway
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5
Turn left onto Coastal Highway
54.4 mi · 1 hr 11 min · Coastal Highway
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6
Turn right onto Byron Butler Parkway
58.3 mi · 1 hr 14 min · Byron Butler Parkway
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7
Keep slight right
8.3 mi · 12 min
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8
Turn left
48 mi · 1 hr 1 min
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9
Take the exit right toward I 75 South: Tampa
1926 ft · 47 sec
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10
Merge slight left
24.7 mi · 26 min
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11
Take the exit slight left toward Florida's Turnpike South, Orlando
165.2 mi · 2 hr 57 min · Florida's Turnpike
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12
Take the exit slight right toward Port Saint Lucie
1 mi · 3 min
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13
Continue on Southwest Bayshore Boulevard
147 m · 15 sec · Southwest Bayshore Boulevard
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14
Turn right onto Southwest Port Saint Lucie Boulevard
1.4 km · 2 min · Southwest Port Saint Lucie Boulevard
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15
Turn left onto Southeast Airoso Boulevard
1.6 mi · 3 min · Southeast Airoso Boulevard
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16
Turn left onto Southwest Carter Avenue
66 m · 9 sec · Southwest Carter Avenue
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17
Arrive at your destination
0 m · 1 sec · Southwest Carter Avenue
Car Route Details
A richer read on the saved driving route between Apalachicola and Port Saint Lucie.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Florida's Turnpike
Take the exit slight left toward Florida's Turnpike South, Orlando
165 mi · 02h 57m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Chance Showers And Thunderstorms leaving Apalachicola and Sunny near Port Saint Lucie.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Apalachicola to Port Saint Lucie?
The road trip is about 412.7 miles (664.2 km) and usually takes 06h 52m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Williston is a useful midpoint, sitting about 206.3 miles from Apalachicola and 206.5 miles from Port Saint Lucie.
How much longer is the road route than the straight-line distance?
The direct path is about 327.7 miles (527.4 km), while the road route adds roughly 85 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $60.39 one way or $120.79 round trip. Estimated CO2 is about 129.4 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms around Apalachicola and Sunny near Port Saint Lucie.
Stop Ideas Near Williston
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Williston.
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Flight Path Map
This map shows the direct air route between Apalachicola and Port Saint Lucie. Straight-line distance: 327.73 mi (527.43 km).
#1 Apalachicola
County seat of Franklin County, Florida, United States
| Population | 2,372 |
| Coordinates | 29.7260000, -84.9856000 |
| Altitude | 4 |
| Country | United States |
#2 Port Saint Lucie
The second most populous city in St.
| Population | 209,715 |
| Coordinates | 27.2939300, -80.3503300 |
| Altitude | 5 |
| Country | United States |
End: Southwest Carter Avenue (-80.350328, 27.294381)
Estimated Travel Time
Distance: 664 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 13h 45m |
| 40 mph (64.37 km/h) | 10h 19m |
| 50 mph (80.47 km/h) | 08h 15m |
| 60 mph (96.56 km/h) | 06h 52m |
| 70 mph (112.65 km/h) | 05h 53m |
| 80 mph (129 km/h) | 05h 08m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $60.39 | $120.79 |
| Mid-grade | $4.60 | $66.92 | $133.84 |
| Premium | $4.90 | $71.29 | $142.57 |
| Diesel | $4.35 | $63.34 | $126.67 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 30, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.