How far is Andrews, SC from Florence, SC?
The driving distance from Andrews, SC to Florence, SC is about 63.5 miles (102.2 km), with a travel time of about 01h 32m by car.
- The straight-line flight distance is about 52.7 miles (84.8 km).
- For a round trip, plan for roughly 03h 05m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM EDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 01h 32m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Williamsburg County, South Carolina, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Driving Route Map
The map below follows the saved road route between Andrews and Florence.
Turn-by-Turn Driving Directions
Step-by-step road directions between Andrews and Florence.
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1
Start on East Main Street
1 mi · 1 min · East Main Street
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2
Continue on US Highway 521
17.4 mi · 20 min · US Highway 521
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3
Turn right onto Martin Luther King Jr Avenue
6.1 mi · 11 min · Martin Luther King Jr Avenue
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4
At the end of the road, turn right onto East Main Street
1454 ft · 32 sec · East Main Street
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5
Turn left onto Eastland Avenue
1.6 mi · 4 min · Eastland Avenue
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6
Turn left onto Dennis Avenue
1611 ft · 47 sec · Dennis Avenue
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7
At the end of the road, turn right onto North Williamsburg County Highway
10.6 mi · 13 min · North Williamsburg County Highway
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8
Continue on South Ron McNair Boulevard
15.2 mi · 24 min · South Ron McNair Boulevard
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9
Continue on South Irby Street
7 mi · 10 min · South Irby Street
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10
Turn right onto Freedom Boulevard
1.3 mi · 2 min · Freedom Boulevard
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11
Turn left onto South Church Street
2.7 mi · 5 min · South Church Street
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12
Turn left
18 m · 4 sec
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13
Turn slight left
38 m · 14 sec
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14
At the end of the road, turn left
14 m · 5 sec
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15
Turn right
15 m · 4 sec
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16
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Andrews and Florence.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
US Highway 521
Continue on US Highway 521
17.4 mi · 00h 20m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Sunny leaving Andrews and Sunny near Florence.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Andrews to Florence?
The road trip is about 63.5 miles (102.2 km) and usually takes 01h 32m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Kingstree is a useful midpoint, sitting about 31.8 miles from Andrews and 31.7 miles from Florence.
How much longer is the road route than the straight-line distance?
The direct path is about 52.7 miles (84.8 km), while the road route adds roughly 10.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM EDT. If you want a more comfortable same-day return, try to leave by 3:24 PM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $9.94 one way or $19.88 round trip. Estimated CO2 is about 22.3 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Andrews and Sunny near Florence.
Stop Ideas Near Kingstree
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Kingstree.
Kingstree
Florence
Charleston, South Carolina
Dillon
Flight Path Map
This map shows the direct air route between Andrews and Florence. Straight-line distance: 52.7 mi (84.82 km).
#1 Andrews
City in South Carolina, United States of America
| Population | 2,866 |
| Coordinates | 33.4512800, -79.5609000 |
| Altitude | 8 |
| Country | United States |
#2 Florence
Civil town in Florence County, Wisconsin
| Population | 38,467 |
| Coordinates | 34.1954300, -79.7625600 |
| Altitude | 42 |
| Country | United States |
End: Florence (-79.76256, 34.19543)
Estimated Travel Time
Distance: 102 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 02h 06m |
| 40 mph (64.37 km/h) | 01h 35m |
| 50 mph (80.47 km/h) | 01h 16m |
| 60 mph (96.56 km/h) | 01h 03m |
| 70 mph (112.65 km/h) | 00h 54m |
| 80 mph (129 km/h) | 00h 47m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $9.94 | $19.88 |
| Mid-grade | $4.43 | $11.12 | $22.23 |
| Premium | $4.78 | $11.99 | $23.99 |
| Diesel | $5.62 | $14.12 | $28.23 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in South Carolina · Apr 11, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.