How far is Amarillo, TX from Santa Fe, TX?
The driving distance from Amarillo, TX to Santa Fe, TX is about 638.5 miles (1027.5 km), with a travel time of about 11h 29m by car.
- The straight-line flight distance is about 563 miles (906.1 km).
- For a round trip, plan for roughly 22h 59m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 11h 29m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census designated place
Route Weather Snapshot
Check the forecast at both ends before you head out.
Areas Of Fog
Partly Sunny then Slight Chance Rain Showers
Driving Route Map
The map below follows the saved road route between Amarillo and Santa Fe.
Turn-by-Turn Driving Directions
Step-by-step road directions between Amarillo and Santa Fe.
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1
Start on East Amarillo Boulevard
5.1 mi · 6 min · East Amarillo Boulevard
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2
Turn right
59 m · 5 sec
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3
Take the ramp slight left
1350 ft · 37 sec
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4
Merge slight left onto North Lakeside Drive
1.9 mi · 2 min · North Lakeside Drive
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5
Turn left onto East Interstate Drive
718 ft · 16 sec · East Interstate Drive
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6
Take the ramp slight left
858 ft · 21 sec
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7
Merge slight left
2.2 mi · 3 min
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8
Take the exit slight right toward US 287 South: Fort Worth
77.2 mi · 1 hr 22 min
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9
Turn slight right onto US Highway 287
13.6 mi · 14 min · US Highway 287
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10
Continue on Burnett Street
1.1 km · 59 sec · Burnett Street
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11
Continue on US Highway 287
13.8 mi · 15 min · US Highway 287
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12
Continue on Avenue F Northwest
2.8 mi · 3 min · Avenue F Northwest
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13
Continue on US Highway 287
54.4 mi · 59 min · US Highway 287
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14
Continue on Martin Luther King Jr Memorial Highway
4.1 mi · 4 min · Martin Luther King Jr Memorial Highway
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15
Continue on US Highway 287 East
40.5 mi · 43 min · US Highway 287 East
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16
Continue on Northwest Freeway
4.6 mi · 5 min · Northwest Freeway
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17
Keep slight right to continue on Northwest Freeway
2984 ft · 42 sec · Northwest Freeway
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18
Merge slight left onto Central Freeway
2.5 mi · 3 min · Central Freeway
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19
Continue on Lloyd Ruby Overpass
1.4 km · 1 min · Lloyd Ruby Overpass
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20
Continue on Central East Freeway
1.4 km · 1 min · Central East Freeway
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21
Keep slight right to continue on Central East Freeway
1.8 mi · 2 min · Central East Freeway
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22
Keep slight right to continue on Central East Freeway
96.6 mi · 1 hr 44 min · Central East Freeway
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23
Continue straight
4.6 mi · 5 min
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24
Merge slight left onto North Freeway
2.3 mi · 3 min · North Freeway
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25
Take the exit slight right toward I 820
2148 ft · 24 sec
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26
Keep slight left to continue on I 820 East
1 mi · 2 min
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27
Merge slight left onto Northeast Loop
1893 ft · 25 sec · Northeast Loop
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28
Take the exit slight left toward I 820 Express East Toll
675 ft · 8 sec
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29
Merge slight left onto I 820 TEXpress
5.5 mi · 6 min · I 820 TEXpress
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30
Continue on SH 121/183 TEXpress
4.4 mi · 4 min · SH 121/183 TEXpress
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31
Continue on SH 183 TEXpress
11.7 mi · 12 min · SH 183 TEXpress
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32
Keep slight right to continue on SH 183 TEXpress
3.3 mi · 3 min · SH 183 TEXpress
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33
Merge slight right onto John W Carpenter Freeway
1.3 km · 51 sec · John W Carpenter Freeway
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34
Merge slight left onto North Stemmons Freeway
3.9 mi · 5 min · North Stemmons Freeway
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35
Take the exit slight right toward Continental Avenue, Commerce Street West
778 ft · 22 sec
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36
Turn straight onto North Stemmons Freeway
764 ft · 18 sec · North Stemmons Freeway
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37
Turn left onto Continental Avenue
1715 ft · 49 sec · Continental Avenue
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38
Turn left onto McKinney Avenue
1118 ft · 25 sec · McKinney Avenue
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39
Take the ramp slight left toward US 75 North
1229 ft · 30 sec
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40
Merge slight left onto Woodall Rodgers Freeway
2170 ft · 37 sec · Woodall Rodgers Freeway
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41
Keep slight right to continue on I 45 South: Houston
2537 ft · 49 sec
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42
Merge slight left onto Julius Schepps Freeway
3.1 mi · 4 min · Julius Schepps Freeway
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43
Keep slight left to continue on Julius Schepps Freeway
234.2 mi · 4 hr 6 min · Julius Schepps Freeway
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44
Continue on Gulf Freeway
28.6 mi · 34 min · Gulf Freeway
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45
Take the exit slight right toward FM 517: Dickinson
1204 ft · 29 sec
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46
Turn straight onto South Gulf Freeway Frontage Road
1.4 km · 1 min · South Gulf Freeway Frontage Road
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47
Turn right
1 mi · 2 min
-
48
Turn left onto FM 646
3.5 mi · 6 min · FM 646
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49
Turn right onto FM 1764
1.5 mi · 2 min · FM 1764
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50
Continue on Farm-to-Market Road 1764
152 m · 16 sec · Farm-to-Market Road 1764
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51
At the end of the road, turn left onto Highway 6
2250 ft · 40 sec · Highway 6
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52
Arrive at your destination
0 m · 1 sec · Highway 6
Car Route Details
A richer read on the saved driving route between Amarillo and Santa Fe.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Julius Schepps Freeway
Keep slight left to continue on Julius Schepps Freeway
234 mi · 04h 06m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Areas Of Fog leaving Amarillo and Partly Sunny then Slight Chance Rain Showers near Santa Fe.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Amarillo to Santa Fe?
The road trip is about 638.5 miles (1027.5 km) and usually takes 11h 29m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Pecan Acres is a useful midpoint, sitting about 319.1 miles from Amarillo and 319.4 miles from Santa Fe.
How much longer is the road route than the straight-line distance?
The direct path is about 563 miles (906.1 km), while the road route adds roughly 75.5 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $86.49 one way or $172.99 round trip. Estimated CO2 is about 200.2 kg one way.
What should you check before leaving?
Before you leave, expect Areas Of Fog around Amarillo and Partly Sunny then Slight Chance Rain Showers near Santa Fe.
Stop Ideas Near Pecan Acres
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
The Keller Watertower
Roanoke City Hall
Niles City Hall Saloon
City Hall Park
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Pecan Acres.
Fort Worth Central Station
Union Station
Dallas, TX
Cleburne
Flight Path Map
This map shows the direct air route between Amarillo and Santa Fe. Straight-line distance: 563.01 mi (906.07 km).
#1 Amarillo
The second most populous city in Texas Panhandle.
| Population | 199,654 |
| Coordinates | 35.2220000, -101.8313000 |
| Altitude | 1118 |
| Country | United States |
#2 Santa Fe
City in Galveston County, Texas, United States
| Population | 13,461 |
| Coordinates | 29.3780100, -95.1057600 |
| Altitude | 9 |
| Country | United States |
End: Santa Fe (-95.10576, 29.37801)
Estimated Travel Time
Distance: 1028 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 21h 16m |
| 40 mph (64.37 km/h) | 15h 57m |
| 50 mph (80.47 km/h) | 12h 46m |
| 60 mph (96.56 km/h) | 10h 38m |
| 70 mph (112.65 km/h) | 09h 07m |
| 80 mph (129 km/h) | 07h 57m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.84 | $86.49 | $172.99 |
| Mid-grade | $4.35 | $97.94 | $195.88 |
| Premium | $4.72 | $106.41 | $212.82 |
| Diesel | $5.78 | $130.13 | $260.27 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Oct 15, 2026