How far is Adrian, MO from Saint Charles, MO?
The driving distance from Adrian, MO to Saint Charles, MO is about 252.3 miles (406 km), with a travel time of about 04h 15m by car.
- The straight-line flight distance is about 210.7 miles (339.1 km).
- For a round trip, plan for roughly 08h 31m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 15m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
This departure sits inside the recommended comfort window for the route.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Cooper County, Missouri, USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Slight Chance Showers And Thunderstorms then Chance Showers And Thunderstorms
Partly Sunny
Driving Route Map
The map below follows the saved road route between Adrian and Saint Charles.
Turn-by-Turn Driving Directions
Step-by-step road directions between Adrian and Saint Charles.
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1
Start on East Main Street
2120 ft · 1 min · East Main Street
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2
Turn right
1073 ft · 32 sec
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3
Continue on East 1st Street
1168 ft · 37 sec · East 1st Street
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4
Take the ramp left toward I 49 North, US 71 North: Kansas City
949 ft · 12 sec
-
5
Merge slight left
18.5 mi · 20 min
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6
Take the exit slight right toward MO 291 North: Lee's Summit
817 ft · 17 sec
-
7
Keep slight right to continue on MO 291 North: Lee's Summit
74 m · 6 sec
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8
Merge slight left
8.3 mi · 12 min
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9
Turn slight left
8.5 mi · 12 min
-
10
Take the exit slight right toward US 50 East, MO 291 North: Sedalia
2911 ft · 53 sec
-
11
Take the exit slight right toward MO 291 North: Independence, Hamblen Road
1191 ft · 37 sec
-
12
Turn left
91 m · 7 sec
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13
Continue straight
9.4 mi · 13 min
-
14
Take the exit slight right toward I 70 East: Saint Louis
2063 ft · 44 sec
-
15
Merge slight left onto Truman/Eisenhower Presidential Highway
1.1 mi · 1 min · Truman/Eisenhower Presidential Highway
-
16
Continue on Dwight D. Eisenhower Highway
52.5 mi · 57 min · Dwight D. Eisenhower Highway
-
17
Continue on U.S. Submarine Veterans' Memorial Highway
32 mi · 34 min · U.S. Submarine Veterans' Memorial Highway
-
18
Keep slight left to continue on U.S. Submarine Veterans' Memorial Highway
22.4 mi · 24 min · U.S. Submarine Veterans' Memorial Highway
-
19
Continue on Dwight D. Eisenhower Highway
1.8 mi · 2 min · Dwight D. Eisenhower Highway
-
20
Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway
1.6 mi · 2 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
-
21
Continue on Sheriff Roger I. Wilson Memorial Highway
1.9 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
-
22
Continue on Dwight D. Eisenhower Highway
99 mi · 1 hr 57 min · Dwight D. Eisenhower Highway
-
23
Take the exit slight right toward I 70 Business, MO 94: First Capitol Drive, Lewis and Clark Trail
653 ft · 14 sec
-
24
Keep slight left to continue on I 70 Business, MO 94 East: First Capitol Drive, Lindenwood University, SSM Health Saint Joseph Hospital
596 ft · 15 sec
-
25
Turn straight onto First Capitol Drive
1.5 km · 2 min · First Capitol Drive
-
26
Turn slight right onto MO 94
1.4 km · 2 min
-
27
Turn left onto South Second Street
1551 ft · 57 sec · South Second Street
-
28
Arrive at your destination
0 m · 1 sec · North Second Street
Car Route Details
A richer read on the saved driving route between Adrian and Saint Charles.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Dwight D. Eisenhower Highway
Continue on Dwight D. Eisenhower Highway
99 mi · 01h 57m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Slight Chance Showers And Thunderstorms then Chance Showers And Thunderstorms leaving Adrian and Partly Sunny near Saint Charles.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Adrian to Saint Charles?
The road trip is about 252.3 miles (406 km) and usually takes 04h 15m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Boonville is a useful midpoint, sitting about 130.7 miles from Adrian and 121.6 miles from Saint Charles.
How much longer is the road route than the straight-line distance?
The direct path is about 210.7 miles (339.1 km), while the road route adds roughly 41.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:28 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $33.56 one way or $67.12 round trip. Estimated CO2 is about 79.1 kg one way.
What should you check before leaving?
Before you leave, expect Slight Chance Showers And Thunderstorms then Chance Showers And Thunderstorms around Adrian and Partly Sunny near Saint Charles.
Stop Ideas Near Boonville
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Boonville.
Sedalia
Jefferson City
Warrensburg
Hermann
Flight Path Map
This map shows the direct air route between Adrian and Saint Charles. Straight-line distance: 210.7 mi (339.09 km).
#1 Adrian
City in Missouri, United States
| Population | 1,601 |
| Coordinates | 38.3975200, -94.3516200 |
| Altitude | 263 |
| Country | United States |
#2 Saint Charles
A city in St.
| Population | 71,761 |
| Coordinates | 38.7839400, -90.4812300 |
| Altitude | 147 |
| Country | United States |
End: North Second Street (-90.481269, 38.783952)
Estimated Travel Time
Distance: 406 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 24m |
| 40 mph (64.37 km/h) | 06h 18m |
| 50 mph (80.47 km/h) | 05h 02m |
| 60 mph (96.56 km/h) | 04h 12m |
| 70 mph (112.65 km/h) | 03h 36m |
| 80 mph (129 km/h) | 03h 08m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $33.56 | $67.12 |
| Mid-grade | $4.25 | $37.85 | $75.70 |
| Premium | $4.65 | $41.42 | $82.84 |
| Diesel | $5.30 | $47.21 | $94.41 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 30, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.