How far is Saint Charles, MO from Adrian, MO?
The driving distance from Saint Charles, MO to Adrian, MO is about 262.3 miles (422.2 km), with a travel time of about 05h 09m by car.
- The straight-line flight distance is about 210.7 miles (339.1 km).
- For a round trip, plan for roughly 10h 19m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 09m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Cooper County, Missouri, USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Cloudy then Chance Showers And Thunderstorms
Chance Showers And Thunderstorms then Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Saint Charles and Adrian.
Turn-by-Turn Driving Directions
Step-by-step road directions between Saint Charles and Adrian.
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1
Start on North Second Street
1551 ft · 1 min · North Second Street
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2
Turn right onto First Capitol Drive
1.4 km · 2 min · First Capitol Drive
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3
Turn left onto First Capitol Drive
1.5 km · 2 min · First Capitol Drive
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4
Take the ramp slight right toward I 70 West
1018 ft · 14 sec
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5
Merge slight left
211.2 mi · 3 hr 59 min
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6
Continue on Truman/Eisenhower Presidential Highway
1.6 mi · 2 min · Truman/Eisenhower Presidential Highway
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7
Take the exit slight right toward I 470 South, MO 291 South: Lee's Summit
1418 ft · 40 sec
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8
Merge slight left
6.4 mi · 8 min
-
9
Keep slight left to continue on MO 291 South: Harrisonville
3.3 mi · 6 min
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10
Take the ramp right toward US 50 West, MO 291 South: Kansas City
2959 ft · 54 sec
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11
Take the exit slight right toward MO 291 South: Jefferson Street, Harrisonville
767 ft · 19 sec
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12
Keep slight left to continue on MO 291 South: Harrisonville
16.9 mi · 25 min
-
13
Continue on Cantrell Road
629 ft · 19 sec · Cantrell Road
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14
Take the exit straight toward I 49 South, US 71 South: Joplin
1138 ft · 28 sec
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15
Merge slight left
18.4 mi · 20 min
-
16
Take the exit slight right toward MO 18: Clinton, Adrian
1039 ft · 24 sec
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17
Turn right onto East 1st Street
665 ft · 25 sec · East 1st Street
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18
Continue straight
1073 ft · 32 sec
-
19
Turn left onto East Main Street
2120 ft · 1 min · East Main Street
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20
Arrive at your destination
0 m · 1 sec · East Main Street
Car Route Details
A richer read on the saved driving route between Saint Charles and Adrian.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 70 West
Merge slight left
211 mi · 03h 59m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Cloudy then Chance Showers And Thunderstorms leaving Saint Charles and Chance Showers And Thunderstorms then Showers And Thunderstorms near Adrian.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Saint Charles to Adrian?
The road trip is about 262.3 miles (422.2 km) and usually takes 05h 09m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Boonville is a useful midpoint, sitting about 131 miles from Saint Charles and 131.4 miles from Adrian.
How much longer is the road route than the straight-line distance?
The direct path is about 210.7 miles (339.1 km), while the road route adds roughly 51.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 6:40 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $34.92 one way or $69.84 round trip. Estimated CO2 is about 82.3 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Cloudy then Chance Showers And Thunderstorms around Saint Charles and Chance Showers And Thunderstorms then Showers And Thunderstorms near Adrian.
Stop Ideas Near Boonville
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Boonville.
Sedalia
Jefferson City
Warrensburg
Hermann
Flight Path Map
This map shows the direct air route between Saint Charles and Adrian. Straight-line distance: 210.7 mi (339.09 km).
#1 Saint Charles
A city in St.
| Population | 71,761 |
| Coordinates | 38.7839400, -90.4812300 |
| Altitude | 147 |
| Country | United States |
#2 Adrian
City in Missouri, United States
| Population | 1,601 |
| Coordinates | 38.3975200, -94.3516200 |
| Altitude | 263 |
| Country | United States |
End: Adrian (-94.35162, 38.39752)
Estimated Travel Time
Distance: 422 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 44m |
| 40 mph (64.37 km/h) | 06h 33m |
| 50 mph (80.47 km/h) | 05h 14m |
| 60 mph (96.56 km/h) | 04h 22m |
| 70 mph (112.65 km/h) | 03h 44m |
| 80 mph (129 km/h) | 03h 16m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $34.92 | $69.84 |
| Mid-grade | $4.25 | $39.38 | $78.77 |
| Premium | $4.65 | $43.10 | $86.19 |
| Diesel | $5.30 | $49.12 | $98.23 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 12, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.