How far is Syracuse, NY from Holtsville, NY?
The driving distance from Syracuse, NY to Holtsville, NY is about 302.4 miles (486.6 km), with a travel time of about 06h 11m by car.
- The straight-line flight distance is about 221.8 miles (357 km).
- For a round trip, plan for roughly 12h 23m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 11m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Sullivan County, New York, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Rain Showers Likely
Chance Rain Showers
Driving Route Map
The map below follows the saved road route between Syracuse and Holtsville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Syracuse and Holtsville.
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1
Start on South State Street
3 m · 6 sec · South State Street
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2
Turn left onto East Genesee Street
1371 ft · 31 sec · East Genesee Street
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3
Turn right onto Almond Street
1445 ft · 28 sec · Almond Street
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4
Turn slight right
90 m · 5 sec
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5
Take the ramp straight toward I 81 South
1057 ft · 26 sec
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6
Merge slight left
2 mi · 3 min
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7
Continue straight
1.2 km · 49 sec
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8
Continue straight
72.6 mi · 1 hr 25 min
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9
Keep slight right to continue on I 81 South: Scranton
53.4 mi · 1 hr 3 min
-
10
Keep slight right to continue on I 84 East, I 380 South, US 6 East: Carbondale, Mt Pocono
1.2 km · 1 min
-
11
Continue on I 84 East, I 380 South: Mount Pocono, Milford
3.7 mi · 5 min
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12
Keep slight right to continue on I 380 South: Mount Pocono
23.6 mi · 26 min
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13
Keep slight left to continue on I 80 East: Stroudsburg
1 mi · 1 min
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14
Merge slight right onto Keystone Shortway
80 mi · 1 hr 37 min · Keystone Shortway
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15
Keep slight right to continue on Christopher Columbus Highway
5.5 mi · 6 min · Christopher Columbus Highway
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16
Keep slight left to continue on I 95 North: George Washington Bridge, New York City
1503 ft · 23 sec
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17
Keep slight right to continue on Leonia, Teaneck
2128 ft · 38 sec
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18
Turn right onto Leonia
1032 ft · 35 sec
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19
Turn straight onto Degraw Avenue
138 m · 9 sec · Degraw Avenue
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20
Continue on Fort Lee Road
1.1 mi · 2 min · Fort Lee Road
-
21
Continue on Main Street
143 m · 13 sec · Main Street
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22
Take the ramp left toward George Washington Bridge
144 m · 13 sec
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23
Merge slight left onto Bergen Boulevard
1552 ft · 29 sec · Bergen Boulevard
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24
Take the exit slight left toward George Washington Bridge Upper Level
95 m · 5 sec
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25
Merge slight left
1649 ft · 20 sec
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26
Keep slight left
1.3 km · 1 min
-
27
Continue on George Washington Bridge (upper level)
3174 ft · 1 min · George Washington Bridge (upper level)
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28
Continue on Trans-Manhattan Expressway
1.2 km · 1 min · Trans-Manhattan Expressway
-
29
Continue on Cross Bronx Expressway
4.7 mi · 6 min · Cross Bronx Expressway
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30
Keep slight right to continue on Cross Bronx Expressway
2 mi · 3 min · Cross Bronx Expressway
-
31
Merge slight left onto Throgs Neck Expressway
3271 ft · 58 sec · Throgs Neck Expressway
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32
Continue on Throgs Neck Bridge
2 mi · 3 min · Throgs Neck Bridge
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33
Continue on Clearview Expressway
3.2 mi · 3 min · Clearview Expressway
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34
Take the exit slight right toward I 495: Manhattan, Eastern Long Island
810 ft · 28 sec
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35
Keep slight left to continue on I 495 East: Long Island Expressway, Eastern Long Island
1448 ft · 39 sec
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36
Merge slight left onto Long Island Expressway
39.2 mi · 53 min · Long Island Expressway
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37
Take the exit slight right toward CR 97: Nicolls Road, Blue Point, Stony Brook
1110 ft · 19 sec
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38
Turn straight onto Express Drive South
3156 ft · 60 sec · Express Drive South
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39
Continue on Express Drive South
789 ft · 18 sec · Express Drive South
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40
Turn right onto Waverly Avenue
1810 ft · 54 sec · Waverly Avenue
-
41
Turn right onto Union Avenue
23 m · 3 sec · Union Avenue
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42
Arrive at your destination
0 m · 1 sec · Union Avenue
Car Route Details
A richer read on the saved driving route between Syracuse and Holtsville.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Keystone Shortway
Merge slight right onto Keystone Shortway
80 mi · 01h 37m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Rain Showers Likely leaving Syracuse and Chance Rain Showers near Holtsville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Syracuse to Holtsville?
The road trip is about 302.4 miles (486.6 km) and usually takes 06h 11m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Tusten is a useful midpoint, sitting about 151.1 miles from Syracuse and 151.3 miles from Holtsville.
How much longer is the road route than the straight-line distance?
The direct path is about 221.8 miles (357 km), while the road route adds roughly 80.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $42.78 one way or $85.55 round trip. Estimated CO2 is about 94.8 kg one way.
What should you check before leaving?
Before you leave, expect Rain Showers Likely around Syracuse and Chance Rain Showers near Holtsville.
Stop Ideas Near Tusten
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Tusten.
Scranton, PA
White Haven, PA
Wilkes-Barre, PA
Poughkeepsie station
Flight Path Map
This map shows the direct air route between Syracuse and Holtsville. Straight-line distance: 221.84 mi (357.02 km).
#1 Syracuse
The fifth most populous city in New York.
| Population | 141,229 |
| Coordinates | 43.0481200, -76.1474200 |
| Altitude | 121 |
| Country | United States |
#2 Holtsville
Census-designated place in Suffolk County, New York
| Population | 19,714 |
| Coordinates | 40.8153800, -73.0451100 |
| Altitude | 32 |
| Country | United States |
End: Holtsville (-73.04511, 40.81538)
Estimated Travel Time
Distance: 487 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 10h 04m |
| 40 mph (64.37 km/h) | 07h 33m |
| 50 mph (80.47 km/h) | 06h 02m |
| 60 mph (96.56 km/h) | 05h 02m |
| 70 mph (112.65 km/h) | 04h 19m |
| 80 mph (129 km/h) | 03h 46m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.01 | $42.78 | $85.55 |
| Mid-grade | $4.48 | $47.81 | $95.62 |
| Premium | $4.86 | $51.87 | $103.73 |
| Diesel | $4.69 | $50.08 | $100.17 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in New York · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.