How far is St. Louis, MO from Winona, MO?
The driving distance from St. Louis, MO to Winona, MO is about 183.2 miles (294.8 km), with a travel time of about 03h 46m by car.
- The straight-line flight distance is about 127.5 miles (205.2 km).
- For a round trip, plan for roughly 07h 33m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 46m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Township in Madison County, Missouri, USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Driving Route Map
The map below follows the saved road route between St. Louis and Winona.
Turn-by-Turn Driving Directions
Step-by-step road directions between St. Louis and Winona.
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1
Start on Market Street
26 m · 4 sec · Market Street
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2
Turn left onto South Tucker Boulevard
1.3 mi · 4 min · South Tucker Boulevard
-
3
Turn straight onto Gravois Avenue
1619 ft · 46 sec · Gravois Avenue
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4
Take the ramp left toward I 55 South: Memphis
626 ft · 15 sec
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5
Merge slight left
32.7 mi · 38 min
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6
Take the exit slight right toward US 67 South: Farmington, Poplar Bluff
914 ft · 20 sec
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7
Keep slight left
729 ft · 18 sec
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8
Enter the roundabout and take exit 1 toward the route
9 m · 1 sec
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9
Exit the roundabout
81.4 mi · 1 hr 34 min
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10
Take the exit slight right
842 ft · 21 sec
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11
Turn right
36 m · 3 sec
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12
Turn right
13.4 mi · 20 min
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13
Continue on North Main Street
25.8 mi · 37 min · North Main Street
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14
Turn right
26.9 mi · 32 min
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15
Turn right
1.2 km · 1 min
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16
Turn right
23 m · 2 sec
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17
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between St. Louis and Winona.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
US 67 South
Exit the roundabout
81.4 mi · 01h 34m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving St. Louis and Clear near Winona.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from St. Louis to Winona?
The road trip is about 183.2 miles (294.8 km) and usually takes 03h 46m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Central is a useful midpoint, sitting about 91.6 miles from St. Louis and 91.6 miles from Winona.
How much longer is the road route than the straight-line distance?
The direct path is about 127.5 miles (205.2 km), while the road route adds roughly 55.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 9:26 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $24.36 one way or $48.72 round trip. Estimated CO2 is about 57.4 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around St. Louis and Clear near Winona.
Stop Ideas Near Central
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Central.
Poplar Bluff
Carbondale station
Du Quoin
Flight Path Map
This map shows the direct air route between St. Louis and Winona. Straight-line distance: 127.53 mi (205.24 km).
#1 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
#2 Winona
City in Missouri, United States
| Population | 1,296 |
| Coordinates | 37.0097700, -91.3234700 |
| Altitude | 284 |
| Country | United States |
End: Winona (-91.32347, 37.00977)
Estimated Travel Time
Distance: 295 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 06m |
| 40 mph (64.37 km/h) | 04h 34m |
| 50 mph (80.47 km/h) | 03h 39m |
| 60 mph (96.56 km/h) | 03h 03m |
| 70 mph (112.65 km/h) | 02h 37m |
| 80 mph (129 km/h) | 02h 17m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $24.36 | $48.72 |
| Mid-grade | $4.25 | $27.47 | $54.95 |
| Premium | $4.65 | $30.06 | $60.13 |
| Diesel | $5.30 | $34.26 | $68.53 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 04, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.