How far is St. Louis, MO from Waynesville, MO?
The driving distance from St. Louis, MO to Waynesville, MO is about 133.7 miles (215.2 km), with a travel time of about 02h 32m by car.
- The straight-line flight distance is about 121.9 miles (196.2 km).
- For a round trip, plan for roughly 05h 05m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 32m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Missouri
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny
Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between St. Louis and Waynesville.
Turn-by-Turn Driving Directions
Step-by-step road directions between St. Louis and Waynesville.
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1
Start on Market Street
1.6 km · 2 min · Market Street
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2
Turn left onto South Jefferson Avenue
1.2 mi · 3 min · South Jefferson Avenue
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3
Take the ramp straight toward I 44 West
1051 ft · 16 sec
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4
Merge slight left onto Officer David Haynes Memorial Highway
2.3 mi · 3 min · Officer David Haynes Memorial Highway
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5
Continue on Officer Michael Barwick Memorial Highway
3.5 mi · 4 min · Officer Michael Barwick Memorial Highway
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6
Continue on Police Officer Robert Stanze Memorial Highway
2.7 mi · 3 min · Police Officer Robert Stanze Memorial Highway
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7
Continue on Police Officer Ernest M. Brockman Sr. Memorial Highway
3.5 mi · 4 min · Police Officer Ernest M. Brockman Sr. Memorial Highway
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8
Continue on Henry Shaw Ozark Corridor
117.2 mi · 2 hr 8 min · Henry Shaw Ozark Corridor
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9
Take the exit slight right toward I 44 Business: Waynesville
1099 ft · 23 sec
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10
Turn straight
1.9 mi · 4 min
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11
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between St. Louis and Waynesville.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
Henry Shaw Ozark Corridor
Continue on Henry Shaw Ozark Corridor
117 mi · 02h 08m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Partly Sunny leaving St. Louis and Showers And Thunderstorms Likely near Waynesville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from St. Louis to Waynesville?
The road trip is about 133.7 miles (215.2 km) and usually takes 02h 32m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Sullivan is a useful midpoint, sitting about 66.8 miles from St. Louis and 66.9 miles from Waynesville.
How much longer is the road route than the straight-line distance?
The direct path is about 121.9 miles (196.2 km), while the road route adds roughly 11.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 1:24 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $17.80 one way or $35.60 round trip. Estimated CO2 is about 41.9 kg one way.
What should you check before leaving?
Before you leave, expect Partly Sunny around St. Louis and Showers And Thunderstorms Likely near Waynesville.
Stop Ideas Near Sullivan
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Sullivan.
Washington
Hermann
Kirkwood
Gateway Transportation Center
Flight Path Map
This map shows the direct air route between St. Louis and Waynesville. Straight-line distance: 121.91 mi (196.19 km).
#1 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
#2 Waynesville
City in Pulaski County, Missouri, United States
| Population | 5,308 |
| Coordinates | 37.8286500, -92.2007200 |
| Altitude | 246 |
| Country | United States |
End: Waynesville (-92.20072, 37.82865)
Estimated Travel Time
Distance: 215 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 04h 27m |
| 40 mph (64.37 km/h) | 03h 20m |
| 50 mph (80.47 km/h) | 02h 40m |
| 60 mph (96.56 km/h) | 02h 13m |
| 70 mph (112.65 km/h) | 01h 54m |
| 80 mph (129 km/h) | 01h 40m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $17.80 | $35.60 |
| Mid-grade | $4.25 | $20.07 | $40.15 |
| Premium | $4.65 | $21.97 | $43.93 |
| Diesel | $5.30 | $25.03 | $50.07 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 30, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.