How far is St. Louis, MO from Louisiana, MO?
The driving distance from St. Louis, MO to Louisiana, MO is about 84 miles (135.2 km), with a travel time of about 01h 56m by car.
- The straight-line flight distance is about 72.9 miles (117.4 km).
- For a round trip, plan for roughly 03h 53m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 01h 56m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Lincoln County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between St. Louis and Louisiana.
Turn-by-Turn Driving Directions
Step-by-step road directions between St. Louis and Louisiana.
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1
Start on Market Street
26 m · 6 sec · Market Street
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2
Turn right onto North Tucker Boulevard
1.3 km · 2 min · North Tucker Boulevard
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3
Turn left onto North 13th Street
1274 ft · 25 sec · North 13th Street
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4
Continue on North 13th Street
111 m · 6 sec · North 13th Street
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5
Continue on North Florissant Avenue
3.5 mi · 6 min · North Florissant Avenue
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6
Take the ramp slight left toward I 70 West
773 ft · 12 sec
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7
Merge slight left onto Mark Twain Expressway
24.8 mi · 32 min · Mark Twain Expressway
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8
Take the exit slight right toward MO 79: Elsberry, Louisiana
725 ft · 15 sec
-
9
Keep slight right to continue on MO 79: Elsberry, Clarksville, Louisiana
572 ft · 12 sec
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10
Turn straight
53.9 mi · 1 hr 14 min
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11
Turn left onto Georgia Street
1194 ft · 26 sec · Georgia Street
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12
Turn right onto North 7th Street
90 m · 15 sec · North 7th Street
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13
Turn right onto Tennessee Street
11 m · 2 sec · Tennessee Street
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14
Arrive at your destination
0 m · 1 sec · Tennessee Street
Car Route Details
A richer read on the saved driving route between St. Louis and Louisiana.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
Longest stretch
Turn straight
53.9 mi · 01h 14m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Mostly Sunny leaving St. Louis and Mostly Sunny near Louisiana.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from St. Louis to Louisiana?
The road trip is about 84 miles (135.2 km) and usually takes 01h 56m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Old Monroe is a useful midpoint, sitting about 42 miles from St. Louis and 42 miles from Louisiana.
How much longer is the road route than the straight-line distance?
The direct path is about 72.9 miles (117.4 km), while the road route adds roughly 11.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 2:36 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $11.16 one way or $22.32 round trip. Estimated CO2 is about 26.3 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around St. Louis and Mostly Sunny near Louisiana.
Stop Ideas Near Old Monroe
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
City Hall Park
City of O'Fallon
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Old Monroe.
Washington
Kirkwood
Alton
Gateway Transportation Center
Flight Path Map
This map shows the direct air route between St. Louis and Louisiana. Straight-line distance: 72.95 mi (117.4 km).
#1 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
#2 Louisiana
Town in Pike County, Missouri, United States
| Population | 3,219 |
| Coordinates | 39.4489400, -91.0515300 |
| Altitude | 148 |
| Country | United States |
End: Louisiana (-91.05153, 39.44894)
Estimated Travel Time
Distance: 135 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 02h 47m |
| 40 mph (64.37 km/h) | 02h 06m |
| 50 mph (80.47 km/h) | 01h 40m |
| 60 mph (96.56 km/h) | 01h 24m |
| 70 mph (112.65 km/h) | 01h 12m |
| 80 mph (129 km/h) | 01h 02m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $11.16 | $22.32 |
| Mid-grade | $4.25 | $12.59 | $25.18 |
| Premium | $4.65 | $13.78 | $27.55 |
| Diesel | $5.30 | $15.70 | $31.40 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 01, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.