How far is St. Louis, MO from Hillsboro, MO?
The driving distance from St. Louis, MO to Hillsboro, MO is about 39.6 miles (63.8 km), with a travel time of about 00h 52m by car.
- The straight-line flight distance is about 33.7 miles (54.2 km).
- For a round trip, plan for roughly 01h 45m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 00h 52m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Missouri
Route Weather Snapshot
Check the forecast at both ends before you head out.
Scattered Rain Showers
Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between St. Louis and Hillsboro.
Turn-by-Turn Driving Directions
Step-by-step road directions between St. Louis and Hillsboro.
-
1
Start on Market Street
26 m · 4 sec · Market Street
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2
Turn left onto South Tucker Boulevard
1.3 mi · 4 min · South Tucker Boulevard
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3
Turn straight onto Gravois Avenue
1619 ft · 46 sec · Gravois Avenue
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4
Take the ramp left toward I 55 South: Memphis
626 ft · 15 sec
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5
Merge slight left
15.3 mi · 19 min
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6
Take the exit slight right toward MO 141: Arnold
1143 ft · 28 sec
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7
Keep slight right to continue on MO 141 North: Arnold, Jefferson College Arnold
615 ft · 15 sec
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8
Merge slight left
3.2 mi · 4 min
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9
Take the exit left toward MO 21 South: Hillsboro
1057 ft · 14 sec
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10
Merge slight left onto Veterans Memorial Highway
17.1 mi · 20 min · Veterans Memorial Highway
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11
Take the exit slight right toward MO A
1791 ft · 46 sec
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12
Turn left
1001 ft · 21 sec
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13
Turn straight onto MO 21 Business
63 m · 9 sec
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14
Turn slight right onto Old State Highway 21
1.2 mi · 3 min · Old State Highway 21
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15
Arrive at your destination
0 m · 1 sec · Old State Highway 21
Car Route Details
A richer read on the saved driving route between St. Louis and Hillsboro.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Veterans Memorial Highway
Merge slight left onto Veterans Memorial Highway
17.1 mi · 00h 20m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Scattered Rain Showers leaving St. Louis and Chance Showers And Thunderstorms near Hillsboro.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from St. Louis to Hillsboro?
The road trip is about 39.6 miles (63.8 km) and usually takes 00h 52m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Arnold is a useful midpoint, sitting about 19.8 miles from St. Louis and 19.8 miles from Hillsboro.
How much longer is the road route than the straight-line distance?
The direct path is about 33.7 miles (54.2 km), while the road route adds roughly 5.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 4:44 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $5.28 one way or $10.56 round trip. Estimated CO2 is about 12.4 kg one way.
What should you check before leaving?
Before you leave, expect Scattered Rain Showers around St. Louis and Chance Showers And Thunderstorms near Hillsboro.
Stop Ideas Near Arnold
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Arnold.
Kirkwood
Gateway Transportation Center
Alton
Washington
Flight Path Map
This map shows the direct air route between St. Louis and Hillsboro. Straight-line distance: 33.69 mi (54.22 km).
#1 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
#2 Hillsboro
City in Missouri, United States
| Population | 3,355 |
| Coordinates | 38.2322800, -90.5629000 |
| Altitude | 242 |
| Country | United States |
End: Hillsboro (-90.5629, 38.23228)
Estimated Travel Time
Distance: 64 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 01h 19m |
| 40 mph (64.37 km/h) | 00h 59m |
| 50 mph (80.47 km/h) | 00h 47m |
| 60 mph (96.56 km/h) | 00h 39m |
| 70 mph (112.65 km/h) | 00h 33m |
| 80 mph (129 km/h) | 00h 29m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $5.28 | $10.56 |
| Mid-grade | $4.25 | $5.95 | $11.91 |
| Premium | $4.65 | $6.52 | $13.03 |
| Diesel | $5.30 | $7.43 | $14.85 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 31, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.