How far is Seneca, WI from La Crosse, WI?
The driving distance from Seneca, WI to La Crosse, WI is about 46.4 miles (74.6 km), with a travel time of about 00h 56m by car.
- The straight-line flight distance is about 39.6 miles (63.8 km).
- For a round trip, plan for roughly 01h 53m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 00h 56m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Village in Vernon and Crawford Counties, Wisconsin
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Seneca and La Crosse.
Turn-by-Turn Driving Directions
Step-by-step road directions between Seneca and La Crosse.
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1
Start on State Highway 27
1.1 mi · 2 min · State Highway 27
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2
Turn right onto County Road E
4.7 mi · 6 min · County Road E
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3
Continue on Spring Street
1851 ft · 56 sec · Spring Street
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4
Turn right onto State Highway 35
4.9 mi · 7 min · State Highway 35
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5
Continue on Great River Road
2.6 mi · 4 min · Great River Road
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6
Continue on Main Street
1.5 km · 1 min · Main Street
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7
Continue on Great River Road
14 mi · 19 min · Great River Road
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8
Continue on State Highway 35
6.1 mi · 8 min · State Highway 35
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9
Continue on Great River Road
3.4 mi · 5 min · Great River Road
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10
Continue on South Main Street
1.4 km · 1 min · South Main Street
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11
Continue on Great River Road
5.6 mi · 8 min · Great River Road
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12
Enter the roundabout and take exit 2 toward Great River Road
33 m · 2 sec · Great River Road
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13
Exit the roundabout onto Great River Road
1346 ft · 29 sec · Great River Road
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14
Enter the roundabout and take exit 2 toward Mormon Coulee Road
45 m · 3 sec · Mormon Coulee Road
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15
Exit the roundabout onto Mormon Coulee Road
2.6 mi · 5 min · Mormon Coulee Road
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16
Enter the roundabout and take exit 2 toward South Avenue
40 m · 4 sec · South Avenue
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17
Exit the roundabout onto South Avenue
947 ft · 27 sec · South Avenue
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18
Enter the roundabout and take exit 2 toward South Avenue
34 m · 3 sec · South Avenue
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19
Exit the roundabout onto South Avenue
2835 ft · 1 min · South Avenue
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20
Enter the roundabout and take exit 1 toward West Avenue South
5 m · 1 sec · West Avenue South
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21
Exit the roundabout onto West Avenue South
1.2 km · 2 min · West Avenue South
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22
Arrive at your destination
0 m · 1 sec · West Avenue South
Car Route Details
A richer read on the saved driving route between Seneca and La Crosse.
Turn-heavy local drive
The route has frequent decision points for its length, so lane choice and turn timing will matter more than cruising speed.
Great River Road
Continue on Great River Road
14 mi · 00h 19m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Sunny leaving Seneca and Sunny near La Crosse.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Seneca to La Crosse?
The road trip is about 46.4 miles (74.6 km) and usually takes 00h 56m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
De Soto is a useful midpoint, sitting about 24.5 miles from Seneca and 21.8 miles from La Crosse.
How much longer is the road route than the straight-line distance?
The direct path is about 39.6 miles (63.8 km), while the road route adds roughly 6.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 4:36 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $6.18 one way or $12.37 round trip. Estimated CO2 is about 14.6 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Seneca and Sunny near La Crosse.
Stop Ideas Near De Soto
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to De Soto.
La Crosse
Winona station
Tomah
Wisconsin Dells
Flight Path Map
This map shows the direct air route between Seneca and La Crosse. Straight-line distance: 39.64 mi (63.8 km).
#1 Seneca
Town in Crawford County, Wisconsin, United States
| Population | 1,051 |
| Coordinates | 43.2649800, -90.9584600 |
| Altitude | 382 |
| Country | United States |
#2 La Crosse
The most populous city in La Crosse County, Wisconsin.
| Population | 51,163 |
| Coordinates | 43.8013600, -91.2395800 |
| Altitude | 204 |
| Country | United States |
End: West Avenue South (-91.239623, 43.801338)
Estimated Travel Time
Distance: 75 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 01h 32m |
| 40 mph (64.37 km/h) | 01h 09m |
| 50 mph (80.47 km/h) | 00h 55m |
| 60 mph (96.56 km/h) | 00h 46m |
| 70 mph (112.65 km/h) | 00h 39m |
| 80 mph (129 km/h) | 00h 34m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $6.18 | $12.37 |
| Mid-grade | $4.25 | $6.97 | $13.95 |
| Premium | $4.65 | $7.63 | $15.27 |
| Diesel | $5.30 | $8.70 | $17.40 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Wisconsin · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.