How far is Senath, MO from St. Louis, MO?
The driving distance from Senath, MO to St. Louis, MO is about 219.4 miles (353.1 km), with a travel time of about 03h 23m by car.
- The straight-line flight distance is about 172.2 miles (277.2 km).
- For a round trip, plan for roughly 06h 46m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 23m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Cape Girardeau County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Showers And Thunderstorms Likely then Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Senath and St. Louis.
Turn-by-Turn Driving Directions
Step-by-step road directions between Senath and St. Louis.
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1
Start on the route
16 m · 9 sec
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2
Turn left onto Commercial Street
2831 ft · 1 min · Commercial Street
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3
Turn left
8.3 mi · 9 min
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4
Enter the roundabout and take exit 1 toward the route
11 m · 1 sec
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5
Exit the roundabout
1.4 mi · 2 min
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6
Turn right onto 1st Street
16.7 mi · 20 min · 1st Street
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7
Take the exit slight right toward I 55 North, US 61 North: Saint Louis
1637 ft · 56 sec
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8
Merge slight left
76 mi · 1 hr 21 min
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9
Keep slight left
101.5 mi · 1 hr 49 min
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10
Continue on Rosa Parks Highway
12.5 mi · 16 min · Rosa Parks Highway
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11
Take the exit slight right toward MO 30 East: Gravois Avenue
1001 ft · 24 sec
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12
Turn slight right onto Gravois Avenue
1044 ft · 27 sec · Gravois Avenue
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13
Continue on South Tucker Boulevard
1.3 mi · 3 min · South Tucker Boulevard
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14
Turn right onto Market Street
26 m · 2 sec · Market Street
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15
Arrive at your destination
0 m · 1 sec · Market Street
Car Route Details
A richer read on the saved driving route between Senath and St. Louis.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 55 North
Keep slight left
102 mi · 01h 49m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Senath and Showers And Thunderstorms Likely then Chance Showers And Thunderstorms near St. Louis.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Senath to St. Louis?
The road trip is about 219.4 miles (353.1 km) and usually takes 03h 23m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Jackson is a useful midpoint, sitting about 109.6 miles from Senath and 109.8 miles from St. Louis.
How much longer is the road route than the straight-line distance?
The direct path is about 172.2 miles (277.2 km), while the road route adds roughly 47.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 10:14 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $29.19 one way or $58.38 round trip. Estimated CO2 is about 68.8 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Senath and Showers And Thunderstorms Likely then Chance Showers And Thunderstorms near St. Louis.
Stop Ideas Near Jackson
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Jackson.
Carbondale station
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Du Quoin
Flight Path Map
This map shows the direct air route between Senath and St. Louis. Straight-line distance: 172.26 mi (277.23 km).
#1 Senath
City in Dunklin County, Missouri, United States
| Population | 1,596 |
| Coordinates | 36.1342300, -90.1598200 |
| Altitude | 78 |
| Country | United States |
#2 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
End: Market Street (-90.197859, 38.627348)
Estimated Travel Time
Distance: 353 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 07h 18m |
| 40 mph (64.37 km/h) | 05h 29m |
| 50 mph (80.47 km/h) | 04h 23m |
| 60 mph (96.56 km/h) | 03h 39m |
| 70 mph (112.65 km/h) | 03h 08m |
| 80 mph (129 km/h) | 02h 44m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $29.19 | $58.38 |
| Mid-grade | $4.25 | $32.92 | $65.84 |
| Premium | $4.65 | $36.02 | $72.04 |
| Diesel | $5.30 | $41.05 | $82.11 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 05, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.