How far is Sanibel, FL from Port Saint Lucie, FL?
The driving distance from Sanibel, FL to Port Saint Lucie, FL is about 156.8 miles (252.4 km), with a travel time of about 03h 06m by car.
- The straight-line flight distance is about 118.4 miles (190.6 km).
- For a round trip, plan for roughly 06h 12m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 06m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Glades County, Florida, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Sunny then Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between Sanibel and Port Saint Lucie.
Turn-by-Turn Driving Directions
Step-by-step road directions between Sanibel and Port Saint Lucie.
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1
Start on the route
35 m · 10 sec
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2
Turn right onto Buttonwood Lane
766 ft · 39 sec · Buttonwood Lane
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3
Turn left onto Periwinkle Way
1.5 km · 2 min · Periwinkle Way
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4
Turn slight right
73 m · 7 sec
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5
Turn straight onto Causeway Road
2222 ft · 1 min · Causeway Road
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6
Continue on Sanibel Causeway
2.9 mi · 6 min · Sanibel Causeway
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7
Continue on McGregor Boulevard
2 mi · 3 min · McGregor Boulevard
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8
Continue on Summerlin Road
6 mi · 9 min · Summerlin Road
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9
Turn right onto Gladiolus Drive
1.5 mi · 2 min · Gladiolus Drive
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10
Continue on Ben C Pratt Six Mile Cypress Parkway
7.8 mi · 12 min · Ben C Pratt Six Mile Cypress Parkway
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11
Take the ramp slight right toward Colonial Boulevard East Bound
1318 ft · 38 sec
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12
Keep slight left
67 m · 8 sec
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13
Merge slight left onto Colonial Boulevard
1709 ft · 35 sec · Colonial Boulevard
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14
Take the exit slight left toward I 75 North: Tampa, I-75 North
2017 ft · 49 sec
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15
Merge slight left
4.3 mi · 5 min
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16
Take the exit slight right toward FL 80: Fort Myers, La Belle
1878 ft · 46 sec
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17
Turn right onto Palm Beach Boulevard
24.2 mi · 35 min · Palm Beach Boulevard
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18
Turn left onto North Bridge Street
4 mi · 6 min · North Bridge Street
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19
Turn right
14.8 mi · 18 min
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20
Continue straight
3.7 mi · 4 min
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21
Take the exit slight left
109 m · 10 sec
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22
Turn left onto Industrial Drive
34.4 mi · 46 min · Industrial Drive
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23
Turn left onto Parrott Avenue
3.1 mi · 6 min · Parrott Avenue
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24
Turn right onto Park Street
24.8 mi · 31 min · Park Street
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25
Turn right onto West Midway Road
4.4 mi · 8 min · West Midway Road
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26
Take the ramp slight right toward I 95 South: West Palm Beach
2661 ft · 1 min
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27
Merge slight left
4.9 mi · 5 min
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28
Take the exit slight right toward Crosstown Parkway
1872 ft · 49 sec
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29
Turn left onto Crosstown Parkway
4.3 mi · 8 min · Crosstown Parkway
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30
Turn right onto Southeast Airoso Boulevard
916 ft · 21 sec · Southeast Airoso Boulevard
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31
Turn right onto Southwest Carter Avenue
66 m · 9 sec · Southwest Carter Avenue
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32
Arrive at your destination
0 m · 1 sec · Southwest Carter Avenue
Car Route Details
A richer read on the saved driving route between Sanibel and Port Saint Lucie.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Industrial Drive
Turn left onto Industrial Drive
34.4 mi · 00h 46m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Sanibel and Mostly Sunny then Showers And Thunderstorms Likely near Port Saint Lucie.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Sanibel to Port Saint Lucie?
The road trip is about 156.8 miles (252.4 km) and usually takes 03h 06m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Moore Haven is a useful midpoint, sitting about 75.6 miles from Sanibel and 81.3 miles from Port Saint Lucie.
How much longer is the road route than the straight-line distance?
The direct path is about 118.4 miles (190.6 km), while the road route adds roughly 38.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 10:48 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $22.94 one way or $45.88 round trip. Estimated CO2 is about 49.1 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Sanibel and Mostly Sunny then Showers And Thunderstorms Likely near Port Saint Lucie.
Stop Ideas Near Moore Haven
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Moore Haven.
Okeechobee
Fort Myers, Florida
Sebring
Port Charlotte, Florida
Flight Path Map
This map shows the direct air route between Sanibel and Port Saint Lucie. Straight-line distance: 118.43 mi (190.6 km).
#1 Sanibel
City in Florida, USA
| Population | 7,429 |
| Coordinates | 26.4489700, -82.0223100 |
| Altitude | 1 |
| Country | United States |
#2 Port Saint Lucie
The second most populous city in St.
| Population | 209,715 |
| Coordinates | 27.2939300, -80.3503300 |
| Altitude | 5 |
| Country | United States |
End: Southwest Carter Avenue (-80.350328, 27.294381)
Estimated Travel Time
Distance: 252 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 13m |
| 40 mph (64.37 km/h) | 03h 55m |
| 50 mph (80.47 km/h) | 03h 08m |
| 60 mph (96.56 km/h) | 02h 36m |
| 70 mph (112.65 km/h) | 02h 14m |
| 80 mph (129 km/h) | 01h 57m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $22.94 | $45.88 |
| Mid-grade | $4.60 | $25.42 | $50.83 |
| Premium | $4.90 | $27.07 | $54.15 |
| Diesel | $4.35 | $24.06 | $48.11 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · May 31, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.