How far is San Luis, AZ from Mesa, AZ?
The driving distance from San Luis, AZ to Mesa, AZ is about 100.7 miles (162.1 km), with a travel time of about 01h 52m by car.
- The straight-line flight distance is about 75.4 miles (121.3 km).
- For a round trip, plan for roughly 03h 44m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM MST.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 01h 52m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census designated place
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between San Luis and Mesa.
Turn-by-Turn Driving Directions
Step-by-step road directions between San Luis and Mesa.
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1
Start on the route
857 ft · 38 sec
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2
Continue on Indian Route 51
1.6 km · 4 min · Indian Route 51
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3
At the end of the road, turn right onto Indian Route 15
33.2 mi · 46 min · Indian Route 15
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4
Continue on South Chuichu Road
5.4 mi · 8 min · South Chuichu Road
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5
Turn right onto West Hanna Street
1 mi · 2 min · West Hanna Street
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6
Turn left onto South Trekell Road
2244 ft · 47 sec · South Trekell Road
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7
Take the ramp right toward I 8 East: Tucson
1841 ft · 45 sec
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8
Merge slight left onto Phoenix Bypass Route
3 mi · 3 min · Phoenix Bypass Route
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9
Keep slight left to continue on I 10 West: Phoenix
1.6 km · 2 min
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10
Merge slight left onto Phoenix-Casa Grande Highway
23.4 mi · 23 min · Phoenix-Casa Grande Highway
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11
Take the exit slight right toward AZ 587 North: Chandler, Gilbert
1404 ft · 54 sec
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12
Turn left
5.8 mi · 9 min
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13
Continue on South Arizona Avenue
11 mi · 19 min · South Arizona Avenue
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14
Continue on South Country Club Drive
4 mi · 7 min · South Country Club Drive
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15
Turn right onto West University Drive
1.6 km · 2 min · West University Drive
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16
Arrive at your destination
0 m · 1 sec · East University Drive
Car Route Details
A richer read on the saved driving route between San Luis and Mesa.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
Indian Route 15
At the end of the road, turn right onto Indian Route 15
33.2 mi · 00h 46m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Mostly Sunny leaving San Luis and Mostly Sunny near Mesa.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from San Luis to Mesa?
The road trip is about 100.7 miles (162.1 km) and usually takes 01h 52m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Arizona City is a useful midpoint, sitting about 45.5 miles from San Luis and 55.2 miles from Mesa.
How much longer is the road route than the straight-line distance?
The direct path is about 75.4 miles (121.3 km), while the road route adds roughly 25.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM MST. If you want a more comfortable same-day return, try to leave by 2:46 PM MST.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $17.63 one way or $35.25 round trip. Estimated CO2 is about 31.6 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around San Luis and Mostly Sunny near Mesa.
Stop Ideas Near Arizona City
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
City of Casa Grande
Eloy City Hall
Arizona City Plaza
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Arizona City.
Maricopa
Phoenix (Airport), Arizona
Phoenix (Greyhound), Arizona
Tucson
Flight Path Map
This map shows the direct air route between San Luis and Mesa. Straight-line distance: 75.38 mi (121.32 km).
#1 San Luis
Town in Yuma County, Arizona, United States
| Population | 36,242 |
| Coordinates | 32.3467300, -112.0409700 |
| Altitude | 547 |
| Country | United States |
#2 Mesa
The fourth most populous city in Arizona and the center of the Mesa metropolitan area.
| Population | 528,159 |
| Coordinates | 33.4222700, -111.8226400 |
| Altitude | 378 |
| Country | United States |
End: East University Drive (-111.82264, 33.422353)
Estimated Travel Time
Distance: 162 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 03h 21m |
| 40 mph (64.37 km/h) | 02h 31m |
| 50 mph (80.47 km/h) | 02h 00m |
| 60 mph (96.56 km/h) | 01h 40m |
| 70 mph (112.65 km/h) | 01h 26m |
| 80 mph (129 km/h) | 01h 15m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.95 | $17.63 | $35.25 |
| Mid-grade | $5.34 | $19.00 | $38.01 |
| Premium | $5.57 | $19.81 | $39.63 |
| Diesel | $6.37 | $22.66 | $45.33 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Arizona · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.