How far is San Antonio, TX from Santa Fe, TX?
The driving distance from San Antonio, TX to Santa Fe, TX is about 230.2 miles (370.4 km), with a travel time of about 04h 12m by car.
- The straight-line flight distance is about 203.9 miles (328.2 km).
- For a round trip, plan for roughly 08h 24m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 12m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Colorado County, Texas, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms
Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between San Antonio and Santa Fe.
Turn-by-Turn Driving Directions
Step-by-step road directions between San Antonio and Santa Fe.
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1
Start on Dolorosa Street
44 m · 5 sec · Dolorosa Street
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2
Continue on West Market Street
1893 ft · 42 sec · West Market Street
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3
Continue on East Market Street
2143 ft · 46 sec · East Market Street
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4
Turn left
111 m · 13 sec
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5
Turn straight onto East Commerce Street
1.2 km · 1 min · East Commerce Street
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6
Keep slight left to continue on East Commerce Street
2.7 mi · 4 min · East Commerce Street
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7
Turn slight right onto East Houston Street
1349 ft · 31 sec · East Houston Street
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8
Turn left onto Interstate 10 East
583 ft · 12 sec · Interstate 10 East
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9
Take the ramp slight left toward I 10 East, US 90 East
874 ft · 21 sec
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10
Merge slight left onto Jose Lopez Freeway
1.8 mi · 2 min · Jose Lopez Freeway
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11
Continue on 90th Infantry Division Highway
22.2 mi · 23 min · 90th Infantry Division Highway
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12
Continue on I 10 East: Houston, Austin, Waco
151.1 mi · 2 hr 34 min
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13
Take the exit slight left toward I 10 Toll: Katy Tollway
1548 ft · 22 sec
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14
Merge slight left onto Katy Tollway
3.2 mi · 4 min · Katy Tollway
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15
Take the exit slight right
1092 ft · 15 sec
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16
Merge slight right onto Katy Freeway
10.3 mi · 13 min · Katy Freeway
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17
Take the exit slight left toward I 45 South: Galveston
819 ft · 20 sec
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18
Merge slight left onto Gulf Freeway
28.4 mi · 33 min · Gulf Freeway
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19
Take the exit slight right toward FM 517: Dickinson
1204 ft · 29 sec
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20
Turn straight onto South Gulf Freeway Frontage Road
1.4 km · 1 min · South Gulf Freeway Frontage Road
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21
Turn right
1 mi · 2 min
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22
Turn left onto FM 646
3.5 mi · 6 min · FM 646
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23
Turn right onto FM 1764
1.5 mi · 2 min · FM 1764
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24
Continue on Farm-to-Market Road 1764
152 m · 16 sec · Farm-to-Market Road 1764
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25
At the end of the road, turn left onto Highway 6
2250 ft · 40 sec · Highway 6
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26
Arrive at your destination
0 m · 1 sec · Highway 6
Car Route Details
A richer read on the saved driving route between San Antonio and Santa Fe.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 10 East
Continue on I 10 East: Houston, Austin, Waco
151 mi · 02h 34m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms leaving San Antonio and Showers And Thunderstorms near Santa Fe.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from San Antonio to Santa Fe?
The road trip is about 230.2 miles (370.4 km) and usually takes 04h 12m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Columbus is a useful midpoint, sitting about 115 miles from San Antonio and 115.2 miles from Santa Fe.
How much longer is the road route than the straight-line distance?
The direct path is about 203.9 miles (328.2 km), while the road route adds roughly 26.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:36 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $30.69 one way or $61.37 round trip. Estimated CO2 is about 72.2 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms around San Antonio and Showers And Thunderstorms near Santa Fe.
Stop Ideas Near Columbus
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Columbus.
Prairie View, TX
Bryan, TX
Houston
Houston, TX
Flight Path Map
This map shows the direct air route between San Antonio and Santa Fe. Straight-line distance: 203.95 mi (328.22 km).
#1 San Antonio
The seventh most populous city in the United States and the center of the San Antonio metropolitan area.
| Population | 1,567,118 |
| Coordinates | 29.4241200, -98.4936300 |
| Altitude | 198 |
| Country | United States |
#2 Santa Fe
City in Galveston County, Texas, United States
| Population | 13,461 |
| Coordinates | 29.3780100, -95.1057600 |
| Altitude | 9 |
| Country | United States |
End: Santa Fe (-95.10576, 29.37801)
Estimated Travel Time
Distance: 370 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 07h 40m |
| 40 mph (64.37 km/h) | 05h 45m |
| 50 mph (80.47 km/h) | 04h 36m |
| 60 mph (96.56 km/h) | 03h 50m |
| 70 mph (112.65 km/h) | 03h 17m |
| 80 mph (129 km/h) | 02h 52m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $30.69 | $61.37 |
| Mid-grade | $4.25 | $34.53 | $69.05 |
| Premium | $4.59 | $37.28 | $74.56 |
| Diesel | $3.99 | $32.42 | $64.85 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.