How far is San Antonio, TX from Panhandle, TX?
The driving distance from San Antonio, TX to Panhandle, TX is about 534.7 miles (860.5 km), with a travel time of about 09h 24m by car.
- The straight-line flight distance is about 442.4 miles (712 km).
- For a round trip, plan for roughly 18h 48m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 09h 24m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Nolan County, Texas, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms
Sunny
Driving Route Map
The map below follows the saved road route between San Antonio and Panhandle.
Turn-by-Turn Driving Directions
Step-by-step road directions between San Antonio and Panhandle.
-
1
Start on Dolorosa Street
44 m · 5 sec · Dolorosa Street
-
2
Continue on West Market Street
1042 ft · 28 sec · West Market Street
-
3
Turn left onto Navarro Street
1.3 km · 2 min · Navarro Street
-
4
Enter the roundabout and take exit 2 toward San Pedro Avenue
26 m · 2 sec · San Pedro Avenue
-
5
Exit the roundabout onto San Pedro Avenue
2891 ft · 1 min · San Pedro Avenue
-
6
Turn left onto West Cypress Street
604 ft · 10 sec · West Cypress Street
-
7
Turn straight onto East Fredericksburg Road
1.2 mi · 2 min · East Fredericksburg Road
-
8
Turn right onto Interstate 10 West
657 ft · 13 sec · Interstate 10 West
-
9
Take the ramp slight left toward I 10 West, US 87 North
553 ft · 14 sec
-
10
Merge slight left onto McDermott Freeway
12.8 mi · 15 min · McDermott Freeway
-
11
Keep slight right
98.7 mi · 1 hr 37 min
-
12
Take the exit slight right toward US 83 North, US 377: Junction, Menard
1665 ft · 44 sec
-
13
Turn right onto North Main Street
29.3 mi · 31 min · North Main Street
-
14
Continue on Frisco Avenue
41.9 mi · 45 min · Frisco Avenue
-
15
Continue on Roberts Avenue
16.5 mi · 18 min · Roberts Avenue
-
16
Turn right onto Hutchings Avenue
118 m · 18 sec · Hutchings Avenue
-
17
Turn left onto North Broadway Street
6.3 mi · 7 min · North Broadway Street
-
18
Turn right
12.3 mi · 13 min
-
19
Turn left onto State Highway 153
29.5 mi · 33 min · State Highway 153
-
20
Keep slight right to continue on State Highway 153
6 m · 1 sec · State Highway 153
-
21
Turn right onto State Highway 70
10.4 mi · 11 min · State Highway 70
-
22
Continue on Lamar Street
1.3 km · 1 min · Lamar Street
-
23
Turn left onto Northwest Georgia Avenue
670 ft · 17 sec · Northwest Georgia Avenue
-
24
Take the ramp slight left toward I 20 West: Midland
104 m · 8 sec
-
25
Merge slight left
6 mi · 6 min
-
26
Take the exit slight right toward US 84 West: Snyder, Lubbock
1721 ft · 20 sec
-
27
Keep slight left
74.2 mi · 1 hr 14 min
-
28
Turn right onto South Avenue F
1 mi · 2 min · South Avenue F
-
29
Keep slight left to continue on North Avenue F
617 ft · 11 sec · North Avenue F
-
30
Turn straight onto Ralls Road
1863 ft · 39 sec · Ralls Road
-
31
Turn left onto East 15th Street
734 ft · 17 sec · East 15th Street
-
32
Turn right onto North US Highway 84
1 mi · 1 min · North US Highway 84
-
33
Continue on Highway 84
20 mi · 20 min · Highway 84
-
34
Continue on Trooper Jerry Don Davis Memorial Highway
4.6 mi · 5 min · Trooper Jerry Don Davis Memorial Highway
-
35
Continue on East Highway 84
6.8 mi · 7 min · East Highway 84
-
36
Continue on Slaton Road
4.5 mi · 6 min · Slaton Road
-
37
Take the exit slight right
1302 ft · 27 sec
-
38
Turn slight right onto Interstate 27
98 m · 6 sec · Interstate 27
-
39
Take the ramp straight
1303 ft · 32 sec
-
40
Merge slight left onto Marshall Formby Memorial Highway
109.9 mi · 1 hr 51 min · Marshall Formby Memorial Highway
-
41
Continue on Canyon Expressway
12.8 mi · 14 min · Canyon Expressway
-
42
Take the exit slight right toward I 40, US 287 South: Albuquerque, Oklahoma City, Fort Worth
607 ft · 11 sec
-
43
Keep slight right to continue on I 40 East, US 287 South: Oklahoma City, Fort Worth
1503 ft · 28 sec
-
44
Merge slight left
4.7 mi · 6 min
-
45
Take the exit slight right toward Loop 335: Lakeside Drive
963 ft · 23 sec
-
46
Turn straight onto East Interstate Drive
1141 ft · 25 sec · East Interstate Drive
-
47
Turn left onto South Lakeside Drive
1.9 mi · 2 min · South Lakeside Drive
-
48
Take the exit slight right toward US 60, I 40 Business: Amarillo Boulevard
1620 ft · 47 sec
-
49
Turn right onto East Amarillo Boulevard
5.9 mi · 7 min · East Amarillo Boulevard
-
50
Continue on East US Highway 60
15.9 mi · 18 min · East US Highway 60
-
51
Turn left onto State Highway 207
955 ft · 16 sec · State Highway 207
-
52
Continue on Franklin Avenue
1394 ft · 29 sec · Franklin Avenue
-
53
Turn left onto Main Street
1148 ft · 34 sec · Main Street
-
54
Turn right onto East 5th Street
29 m · 4 sec · East 5th Street
-
55
Arrive at your destination
0 m · 1 sec · East 5th Street
Car Route Details
A richer read on the saved driving route between San Antonio and Panhandle.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Marshall Formby Memorial Highway
Merge slight left onto Marshall Formby Memorial Highway
110 mi · 01h 51m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms leaving San Antonio and Sunny near Panhandle.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from San Antonio to Panhandle?
The road trip is about 534.7 miles (860.5 km) and usually takes 09h 24m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Roscoe is a useful midpoint, sitting about 267.6 miles from San Antonio and 267.1 miles from Panhandle.
How much longer is the road route than the straight-line distance?
The direct path is about 442.4 miles (712 km), while the road route adds roughly 92.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $71.31 one way or $142.62 round trip. Estimated CO2 is about 167.7 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms around San Antonio and Sunny near Panhandle.
Stop Ideas Near Roscoe
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Mustang Harbor Splash Pad
City of Sweetwater
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Roscoe.
Flight Path Map
This map shows the direct air route between San Antonio and Panhandle. Straight-line distance: 442.39 mi (711.95 km).
#1 San Antonio
The seventh most populous city in the United States and the center of the San Antonio metropolitan area.
| Population | 1,567,118 |
| Coordinates | 29.4241200, -98.4936300 |
| Altitude | 198 |
| Country | United States |
#2 Panhandle
Town in Texas, United States
| Population | 2,341 |
| Coordinates | 35.3456000, -101.3804400 |
| Altitude | 1054 |
| Country | United States |
End: Panhandle (-101.38044, 35.3456)
Estimated Travel Time
Distance: 861 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 17h 49m |
| 40 mph (64.37 km/h) | 13h 22m |
| 50 mph (80.47 km/h) | 10h 41m |
| 60 mph (96.56 km/h) | 08h 54m |
| 70 mph (112.65 km/h) | 07h 38m |
| 80 mph (129 km/h) | 06h 40m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $71.31 | $142.62 |
| Mid-grade | $4.25 | $80.24 | $160.47 |
| Premium | $4.59 | $86.63 | $173.26 |
| Diesel | $3.99 | $75.35 | $150.70 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.