How far is Panhandle, TX from San Antonio, TX?
The driving distance from Panhandle, TX to San Antonio, TX is about 508 miles (817.5 km), with a travel time of about 08h 04m by car.
- The straight-line flight distance is about 442.4 miles (712 km).
- For a round trip, plan for roughly 16h 08m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 08h 04m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Nolan County, Texas, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Panhandle and San Antonio.
Turn-by-Turn Driving Directions
Step-by-step road directions between Panhandle and San Antonio.
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1
Start on East 5th Street
29 m · 9 sec · East 5th Street
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2
Turn left onto Main Street
1148 ft · 34 sec · Main Street
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3
Turn right onto West Broadway Street
764 ft · 13 sec · West Broadway Street
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4
Turn straight
1585 ft · 29 sec
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5
Turn right onto West US Highway 60
15.9 mi · 16 min · West US Highway 60
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6
Continue on East Amarillo Boulevard
6 mi · 7 min · East Amarillo Boulevard
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7
Turn left
59 m · 5 sec
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8
Take the ramp slight left
1350 ft · 37 sec
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9
Merge slight left onto North Lakeside Drive
1.8 mi · 2 min · North Lakeside Drive
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10
Take the exit slight right
75 m · 7 sec
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11
Turn slight right onto East Interstate Drive
2810 ft · 56 sec · East Interstate Drive
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12
Take the ramp slight left
1118 ft · 27 sec
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13
Merge slight left
4.3 mi · 5 min
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14
Take the exit slight right toward I 27 South, US 87, US 60, US 287 North: Canyon, Lubbock, Dumas, Pampa, Downtown
143 m · 9 sec
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15
Keep slight left to continue on I 27 South, US 87 South, US 60 West: Canyon, Lubbock
2952 ft · 1 min
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16
Merge slight left onto Canyon Expressway
13.2 mi · 15 min · Canyon Expressway
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17
Keep slight left to continue on Marshall Formby Memorial Highway
103.7 mi · 1 hr 44 min · Marshall Formby Memorial Highway
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18
Take the exit slight right toward Loop 289
1011 ft · 25 sec
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19
Turn straight onto North Interstate 27
2536 ft · 57 sec · North Interstate 27
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20
Turn left onto North Loop 289
1110 ft · 22 sec · North Loop 289
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21
Take the ramp slight left
885 ft · 22 sec
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22
Merge slight left
7.5 mi · 9 min
-
23
Take the exit slight right toward Spur 331: Southeast Drive
128 m · 10 sec
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24
Keep slight right to continue on Spur 331: Southeast Drive
71 m · 6 sec
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25
Turn straight onto Southeast Loop 289
563 ft · 14 sec · Southeast Loop 289
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26
Turn right onto Southeast Drive
1.9 mi · 3 min · Southeast Drive
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27
Merge slight right onto Slaton Road
996 ft · 13 sec · Slaton Road
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28
Continue on East Highway 84
6.9 mi · 7 min · East Highway 84
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29
Continue on Trooper Jerry Don Davis Memorial Highway
4.5 mi · 5 min · Trooper Jerry Don Davis Memorial Highway
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30
Continue on East Highway 84
20 mi · 20 min · East Highway 84
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31
Continue on North US Highway 84
1 mi · 1 min · North US Highway 84
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32
Turn left onto East 15th Street
734 ft · 15 sec · East 15th Street
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33
Turn right onto Ralls Road
1863 ft · 38 sec · Ralls Road
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34
Turn straight onto North Avenue F
1.1 mi · 2 min · North Avenue F
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35
At the end of the road, turn left onto US Highway 84
73.9 mi · 1 hr 14 min · US Highway 84
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36
Keep slight left to continue on I 20 East, US 84 East: Abilene
6.5 mi · 7 min
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37
Take the exit slight right toward SH 70 South, SH 70 Business: Sweetwater, San Angelo
737 ft · 18 sec
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38
Turn slight left onto Southwest Georgia Avenue
624 ft · 17 sec · Southwest Georgia Avenue
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39
Turn right onto Lamar Street
1.2 km · 1 min · Lamar Street
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40
Continue on State Highway 70
10.4 mi · 11 min · State Highway 70
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41
Turn left onto State Highway 153
29.5 mi · 33 min · State Highway 153
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42
Turn right
12.3 mi · 13 min
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43
Turn left
6.3 mi · 7 min
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44
At the end of the road, turn right onto Hutchings Avenue
118 m · 18 sec · Hutchings Avenue
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45
Turn left onto South 7th Street
16.5 mi · 18 min · South 7th Street
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46
Continue on Grassmeyer Street
41.9 mi · 45 min · Grassmeyer Street
-
47
Continue on Ellis Street
29.4 mi · 31 min · Ellis Street
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48
Take the exit left toward I 10 East: San Antonio
40 mi · 38 min
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49
Continue straight
54.3 mi · 55 min
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50
Keep slight right
17.4 mi · 20 min
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51
Keep slight right to continue on McDermott Freeway
1.7 mi · 2 min · McDermott Freeway
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52
Take the exit slight right toward Santa Rosa Street, Downtown
2505 ft · 1 min
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53
Turn straight onto North Pecos-La Trinidad
804 ft · 16 sec · North Pecos-La Trinidad
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54
Keep slight right to continue on North Pecos-La Trinidad
2963 ft · 1 min · North Pecos-La Trinidad
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55
Turn left onto Dolorosa Street
2582 ft · 56 sec · Dolorosa Street
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56
Arrive at your destination
0 m · 1 sec · Dolorosa Street
Car Route Details
A richer read on the saved driving route between Panhandle and San Antonio.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Marshall Formby Memorial Highway
Keep slight left to continue on Marshall Formby Memorial Highway
104 mi · 01h 44m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Sunny leaving Panhandle and Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms near San Antonio.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Panhandle to San Antonio?
The road trip is about 508 miles (817.5 km) and usually takes 08h 04m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Roscoe is a useful midpoint, sitting about 267.7 miles from Panhandle and 240.2 miles from San Antonio.
How much longer is the road route than the straight-line distance?
The direct path is about 442.4 miles (712 km), while the road route adds roughly 65.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $67.72 one way or $135.44 round trip. Estimated CO2 is about 159.3 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Panhandle and Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms near San Antonio.
Stop Ideas Near Roscoe
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Mustang Harbor Splash Pad
City of Sweetwater
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Roscoe.
Flight Path Map
This map shows the direct air route between Panhandle and San Antonio. Straight-line distance: 442.39 mi (711.95 km).
#1 Panhandle
Town in Texas, United States
| Population | 2,341 |
| Coordinates | 35.3456000, -101.3804400 |
| Altitude | 1054 |
| Country | United States |
#2 San Antonio
The seventh most populous city in the United States and the center of the San Antonio metropolitan area.
| Population | 1,567,118 |
| Coordinates | 29.4241200, -98.4936300 |
| Altitude | 198 |
| Country | United States |
End: Dolorosa Street (-98.493645, 29.424163)
Estimated Travel Time
Distance: 818 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 16h 55m |
| 40 mph (64.37 km/h) | 12h 42m |
| 50 mph (80.47 km/h) | 10h 09m |
| 60 mph (96.56 km/h) | 08h 27m |
| 70 mph (112.65 km/h) | 07h 15m |
| 80 mph (129 km/h) | 06h 20m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $67.72 | $135.44 |
| Mid-grade | $4.25 | $76.20 | $152.39 |
| Premium | $4.59 | $82.27 | $164.54 |
| Diesel | $3.99 | $71.55 | $143.11 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.