How far is San Antonio, TX from Lamesa, TX?
The driving distance from San Antonio, TX to Lamesa, TX is about 346.2 miles (557.1 km), with a travel time of about 06h 00m by car.
- The straight-line flight distance is about 307 miles (494 km).
- For a round trip, plan for roughly 12h 01m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 00m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Cloudy
Mostly Sunny
Driving Route Map
The map below follows the saved road route between San Antonio and Lamesa.
Turn-by-Turn Driving Directions
Step-by-step road directions between San Antonio and Lamesa.
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1
Start on Dolorosa Street
44 m · 5 sec · Dolorosa Street
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2
Continue on West Market Street
1042 ft · 28 sec · West Market Street
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3
Turn left onto Navarro Street
1.3 km · 2 min · Navarro Street
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4
Enter the roundabout and take exit 2 toward San Pedro Avenue
26 m · 2 sec · San Pedro Avenue
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5
Exit the roundabout onto San Pedro Avenue
2891 ft · 1 min · San Pedro Avenue
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6
Turn left onto West Cypress Street
604 ft · 10 sec · West Cypress Street
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7
Turn straight onto East Fredericksburg Road
1.2 mi · 2 min · East Fredericksburg Road
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8
Turn right onto Interstate 10 West
657 ft · 13 sec · Interstate 10 West
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9
Take the ramp slight left toward I 10 West, US 87 North
553 ft · 14 sec
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10
Merge slight left onto McDermott Freeway
12.8 mi · 15 min · McDermott Freeway
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11
Keep slight right
98.7 mi · 1 hr 37 min
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12
Take the exit slight right toward US 83 North, US 377: Junction, Menard
1665 ft · 44 sec
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13
Turn right onto North Main Street
29.3 mi · 31 min · North Main Street
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14
Continue on Frisco Avenue
21.5 mi · 23 min · Frisco Avenue
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15
Turn left onto West Broadway Street
39.2 mi · 40 min · West Broadway Street
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16
Continue on South Bryant Boulevard
4.1 mi · 6 min · South Bryant Boulevard
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17
Continue on South Koenigheim Street
1.4 mi · 2 min · South Koenigheim Street
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18
Continue on North Bryant Boulevard
4.3 mi · 6 min · North Bryant Boulevard
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19
Continue on US Highway 87 North
23.2 mi · 24 min · US Highway 87 North
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20
Continue straight
15.8 mi · 17 min
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21
Turn straight onto US Highway 87 North
52 mi · 52 min · US Highway 87 North
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22
Continue on North US Highway 87
15.2 mi · 15 min · North US Highway 87
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23
Continue on William Crooker Highway
4.3 mi · 4 min · William Crooker Highway
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24
Continue on South US Highway 87
18.1 mi · 18 min · South US Highway 87
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25
Continue on South Dallas Avenue
1.3 mi · 2 min · South Dallas Avenue
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26
Continue on South Lynn Avenue
1.2 mi · 1 min · South Lynn Avenue
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27
Turn left
49 m · 12 sec
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28
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between San Antonio and Lamesa.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
McDermott Freeway
Keep slight right
98.7 mi · 01h 37m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Mostly Cloudy leaving San Antonio and Mostly Sunny near Lamesa.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from San Antonio to Lamesa?
The road trip is about 346.2 miles (557.1 km) and usually takes 06h 00m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Live Oak is a useful midpoint, sitting about 173.2 miles from San Antonio and 173 miles from Lamesa.
How much longer is the road route than the straight-line distance?
The direct path is about 307 miles (494 km), while the road route adds roughly 39.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $46.18 one way or $92.36 round trip. Estimated CO2 is about 108.6 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Cloudy around San Antonio and Mostly Sunny near Lamesa.
Flight Path Map
This map shows the direct air route between San Antonio and Lamesa. Straight-line distance: 306.99 mi (494.05 km).
#1 San Antonio
The seventh most populous city in the United States and the center of the San Antonio metropolitan area.
| Population | 1,567,118 |
| Coordinates | 29.4241200, -98.4936300 |
| Altitude | 198 |
| Country | United States |
#2 Lamesa
City in Texas, USA
| Population | 9,131 |
| Coordinates | 32.7376000, -101.9509900 |
| Altitude | 912 |
| Country | United States |
End: Lamesa (-101.95099, 32.7376)
Estimated Travel Time
Distance: 557 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 32m |
| 40 mph (64.37 km/h) | 08h 39m |
| 50 mph (80.47 km/h) | 06h 55m |
| 60 mph (96.56 km/h) | 05h 46m |
| 70 mph (112.65 km/h) | 04h 56m |
| 80 mph (129 km/h) | 04h 19m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $46.18 | $92.36 |
| Mid-grade | $4.25 | $51.96 | $103.92 |
| Premium | $4.59 | $56.10 | $112.20 |
| Diesel | $3.99 | $48.79 | $97.59 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Apr 26, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.