How far is Lamesa, TX from San Antonio, TX?
The driving distance from Lamesa, TX to San Antonio, TX is about 348.1 miles (560.2 km), with a travel time of about 05h 15m by car.
- The straight-line flight distance is about 307 miles (494 km).
- For a round trip, plan for roughly 10h 30m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 15m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Texas
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Cloudy
Driving Route Map
The map below follows the saved road route between Lamesa and San Antonio.
Turn-by-Turn Driving Directions
Step-by-step road directions between Lamesa and San Antonio.
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1
Start on the route
49 m · 14 sec
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2
At the end of the road, turn right onto North Lynn Avenue
1.3 mi · 1 min · North Lynn Avenue
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3
Continue on South Dallas Avenue
1.3 mi · 1 min · South Dallas Avenue
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4
Continue on South US Highway 87
18.1 mi · 18 min · South US Highway 87
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5
Continue on William Crooker Highway
1.4 mi · 1 min · William Crooker Highway
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6
Continue on North US Highway 87
18.1 mi · 18 min · North US Highway 87
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7
Continue on William B Crooker Memorial Highway
52.1 mi · 52 min · William B Crooker Memorial Highway
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8
Continue on 4th Street
1.2 mi · 2 min · 4th Street
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9
Continue on US Highway 87 South
14.6 mi · 15 min · US Highway 87 South
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10
Continue straight
72.2 mi · 1 hr 18 min
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11
Turn right onto South Main Street
21.5 mi · 23 min · South Main Street
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12
Continue on Ellis Street
29.4 mi · 31 min · Ellis Street
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13
Take the exit left toward I 10 East: San Antonio
40 mi · 38 min
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14
Continue straight
54.3 mi · 55 min
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15
Keep slight right
17.4 mi · 20 min
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16
Keep slight right to continue on McDermott Freeway
1.7 mi · 2 min · McDermott Freeway
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17
Take the exit slight right toward Santa Rosa Street, Downtown
2505 ft · 1 min
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18
Turn straight onto North Pecos-La Trinidad
804 ft · 16 sec · North Pecos-La Trinidad
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19
Keep slight right to continue on North Pecos-La Trinidad
2963 ft · 1 min · North Pecos-La Trinidad
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20
Turn left onto Dolorosa Street
2582 ft · 56 sec · Dolorosa Street
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21
Arrive at your destination
0 m · 1 sec · Dolorosa Street
Car Route Details
A richer read on the saved driving route between Lamesa and San Antonio.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
US Highway 87 South
Continue straight
72.2 mi · 01h 18m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Lamesa and Mostly Cloudy near San Antonio.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Lamesa to San Antonio?
The road trip is about 348.1 miles (560.2 km) and usually takes 05h 15m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Live Oak is a useful midpoint, sitting about 173.2 miles from Lamesa and 174.9 miles from San Antonio.
How much longer is the road route than the straight-line distance?
The direct path is about 307 miles (494 km), while the road route adds roughly 41.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 6:30 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $46.41 one way or $92.81 round trip. Estimated CO2 is about 109.1 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Lamesa and Mostly Cloudy near San Antonio.
Flight Path Map
This map shows the direct air route between Lamesa and San Antonio. Straight-line distance: 306.99 mi (494.05 km).
#1 Lamesa
City in Texas, USA
| Population | 9,131 |
| Coordinates | 32.7376000, -101.9509900 |
| Altitude | 912 |
| Country | United States |
#2 San Antonio
The seventh most populous city in the United States and the center of the San Antonio metropolitan area.
| Population | 1,567,118 |
| Coordinates | 29.4241200, -98.4936300 |
| Altitude | 198 |
| Country | United States |
End: Dolorosa Street (-98.493645, 29.424163)
Estimated Travel Time
Distance: 560 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 35m |
| 40 mph (64.37 km/h) | 08h 42m |
| 50 mph (80.47 km/h) | 06h 57m |
| 60 mph (96.56 km/h) | 05h 48m |
| 70 mph (112.65 km/h) | 04h 58m |
| 80 mph (129 km/h) | 04h 20m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $46.41 | $92.81 |
| Mid-grade | $4.25 | $52.21 | $104.43 |
| Premium | $4.59 | $56.38 | $112.75 |
| Diesel | $3.99 | $49.03 | $98.07 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Apr 26, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.