How far is San Antonio, TX from Knox City, TX?
The driving distance from San Antonio, TX to Knox City, TX is about 333.5 miles (536.7 km), with a travel time of about 06h 12m by car.
- The straight-line flight distance is about 286.8 miles (461.6 km).
- For a round trip, plan for roughly 12h 24m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 12m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Concho County, Texas, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny
Driving Route Map
The map below follows the saved road route between San Antonio and Knox City.
Turn-by-Turn Driving Directions
Step-by-step road directions between San Antonio and Knox City.
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1
Start on Dolorosa Street
44 m · 5 sec · Dolorosa Street
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2
Continue on West Market Street
1042 ft · 28 sec · West Market Street
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3
Turn left onto Navarro Street
1.3 km · 2 min · Navarro Street
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4
Enter the roundabout and take exit 2 toward San Pedro Avenue
26 m · 2 sec · San Pedro Avenue
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5
Exit the roundabout onto San Pedro Avenue
2891 ft · 1 min · San Pedro Avenue
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6
Turn left onto West Cypress Street
604 ft · 10 sec · West Cypress Street
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7
Turn straight onto East Fredericksburg Road
1.2 mi · 2 min · East Fredericksburg Road
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8
Turn right onto Interstate 10 West
657 ft · 13 sec · Interstate 10 West
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9
Take the ramp slight left toward I 10 West, US 87 North
553 ft · 14 sec
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10
Merge slight left onto McDermott Freeway
12.8 mi · 15 min · McDermott Freeway
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11
Keep slight right
98.7 mi · 1 hr 37 min
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12
Take the exit slight right toward US 83 North, US 377: Junction, Menard
1665 ft · 44 sec
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13
Turn right onto North Main Street
29.3 mi · 31 min · North Main Street
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14
Continue on Frisco Avenue
41.9 mi · 45 min · Frisco Avenue
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15
Continue on Roberts Avenue
16.5 mi · 18 min · Roberts Avenue
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16
Turn right onto Hutchings Avenue
1.5 km · 2 min · Hutchings Avenue
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17
Turn straight onto US 83 North
78.9 mi · 1 hr 27 min
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18
Turn slight right onto East Court Plaza
589 ft · 8 sec · East Court Plaza
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19
Continue on Commercial Avenue
15.9 mi · 18 min · Commercial Avenue
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20
Take the exit slight right
1551 ft · 45 sec
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21
Turn left
538 ft · 14 sec
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22
Turn left
7.5 mi · 11 min
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23
Turn right
10.8 mi · 16 min
-
24
Continue on State Highway 6
12.7 mi · 19 min · State Highway 6
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25
Continue on Grand Central Avenue
1.3 km · 1 min · Grand Central Avenue
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26
Continue on State Highway 6
1.6 mi · 2 min · State Highway 6
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27
Continue on South Central Avenue
1 mi · 2 min · South Central Avenue
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28
Turn right onto East Main Street
14 m · 1 sec · East Main Street
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29
Arrive at your destination
0 m · 1 sec · East Main Street
Car Route Details
A richer read on the saved driving route between San Antonio and Knox City.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
McDermott Freeway
Keep slight right
98.7 mi · 01h 37m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Partly Sunny leaving San Antonio and Sunny near Knox City.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from San Antonio to Knox City?
The road trip is about 333.5 miles (536.7 km) and usually takes 06h 12m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Eden is a useful midpoint, sitting about 167 miles from San Antonio and 166.5 miles from Knox City.
How much longer is the road route than the straight-line distance?
The direct path is about 286.8 miles (461.6 km), while the road route adds roughly 46.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $44.48 one way or $88.96 round trip. Estimated CO2 is about 104.6 kg one way.
What should you check before leaving?
Before you leave, expect Partly Sunny around San Antonio and Sunny near Knox City.
Flight Path Map
This map shows the direct air route between San Antonio and Knox City. Straight-line distance: 286.8 mi (461.56 km).
#1 San Antonio
The seventh most populous city in the United States and the center of the San Antonio metropolitan area.
| Population | 1,567,118 |
| Coordinates | 29.4241200, -98.4936300 |
| Altitude | 198 |
| Country | United States |
#2 Knox City
City in Knox County, Texas, United States
| Population | 1,120 |
| Coordinates | 33.4181500, -99.8189800 |
| Altitude | 466 |
| Country | United States |
End: Knox City (-99.81898, 33.41815)
Estimated Travel Time
Distance: 537 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 06m |
| 40 mph (64.37 km/h) | 08h 20m |
| 50 mph (80.47 km/h) | 06h 40m |
| 60 mph (96.56 km/h) | 05h 33m |
| 70 mph (112.65 km/h) | 04h 45m |
| 80 mph (129 km/h) | 04h 09m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $44.48 | $88.96 |
| Mid-grade | $4.25 | $50.05 | $100.09 |
| Premium | $4.59 | $54.04 | $108.07 |
| Diesel | $3.99 | $47.00 | $94.00 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Jun 01, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.