How far is Saltillo, MS from Oxford, MS?
The driving distance from Saltillo, MS to Oxford, MS is about 297.1 miles (478.2 km), with a travel time of about 04h 48m by car.
- The straight-line flight distance is about 250.4 miles (402.9 km).
- For a round trip, plan for roughly 09h 37m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 48m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Mississippi, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Driving Route Map
The map below follows the saved road route between Saltillo and Oxford.
Turn-by-Turn Driving Directions
Step-by-step road directions between Saltillo and Oxford.
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1
Start on East Mobile Street
153 m · 12 sec · East Mobile Street
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2
Turn right onto North 3rd Avenue
1.2 mi · 3 min · North 3rd Avenue
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3
Turn sharp left
1.2 mi · 2 min
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4
Take the ramp slight left toward Tupelo
1357 ft · 35 sec
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5
Merge slight left
19.9 mi · 24 min
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6
Continue straight
1.4 mi · 2 min
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7
Continue straight
2.2 mi · 2 min
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8
Continue straight
1.5 mi · 2 min
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9
Continue straight
1.1 km · 49 sec
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10
Continue straight
1.4 mi · 2 min
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11
Continue on US Highway 45 Alternate
35.7 mi · 44 min · US Highway 45 Alternate
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12
Take the exit slight right toward US 82 West, MS 12 West, MS 25 South: Starkville
11.8 mi · 13 min
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13
Take the exit slight right toward MS 25 South: Louisville
5 mi · 7 min
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14
Continue straight
26.8 mi · 31 min
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15
Take the exit slight right
92.5 mi · 1 hr 46 min
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16
Take the exit slight right
1078 ft · 26 sec
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17
Merge slight left
6.1 mi · 8 min
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18
Keep slight left to continue on I 55 South: McComb, New Orleans
53.8 mi · 58 min
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19
Take the exit slight right toward US 84: South Brookhaven, Natchez
1459 ft · 36 sec
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20
Keep slight right to continue on US 84: South Brookhaven, Natchez
125 m · 10 sec
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21
Merge slight left
22.7 mi · 26 min
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22
Turn left
1.4 mi · 3 min
-
23
Turn left
1.9 mi · 2 min
-
24
Turn right onto Yap 3 Road
2.6 mi · 6 min · Yap 3 Road
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25
Continue on Gloster Road
3.8 mi · 9 min · Gloster Road
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26
At the end of the road, turn right onto Gloster Road
2.8 mi · 7 min · Gloster Road
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27
Continue on Oxford-Meadville Road
6.3 mi · 15 min · Oxford-Meadville Road
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28
Arrive at your destination
0 m · 1 sec · Oxford-Meadville Road
Car Route Details
A richer read on the saved driving route between Saltillo and Oxford.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
MS 25 South
Take the exit slight right
92.5 mi · 01h 46m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Saltillo and Sunny near Oxford.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Saltillo to Oxford?
The road trip is about 297.1 miles (478.2 km) and usually takes 04h 48m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Wiggins is a useful midpoint, sitting about 151.9 miles from Saltillo and 145.3 miles from Oxford.
How much longer is the road route than the straight-line distance?
The direct path is about 250.4 miles (402.9 km), while the road route adds roughly 46.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 7:22 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $39.69 one way or $79.38 round trip. Estimated CO2 is about 93.1 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Saltillo and Sunny near Oxford.
Stop Ideas Near Wiggins
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Wiggins.
Union Station
Yazoo City
Union Station
Greenwood
Flight Path Map
This map shows the direct air route between Saltillo and Oxford. Straight-line distance: 250.36 mi (402.92 km).
#1 Saltillo
Human settlement in Lee County, Mississippi, United States of America
| Population | 5,071 |
| Coordinates | 34.3764900, -88.6817200 |
| Altitude | 98 |
| Country | United States |
#2 Oxford
City in Lafayette County, Mississippi, United States of America
| Population | 28,635 |
| Coordinates | 31.2679500, -90.8981600 |
| Altitude | 128 |
| Country | United States |
End: Oxford-Meadville Road (-90.898562, 31.26795)
Estimated Travel Time
Distance: 478 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 54m |
| 40 mph (64.37 km/h) | 07h 25m |
| 50 mph (80.47 km/h) | 05h 56m |
| 60 mph (96.56 km/h) | 04h 57m |
| 70 mph (112.65 km/h) | 04h 14m |
| 80 mph (129 km/h) | 03h 42m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $39.69 | $79.38 |
| Mid-grade | $4.26 | $44.63 | $89.27 |
| Premium | $4.63 | $48.47 | $96.94 |
| Diesel | $5.42 | $56.75 | $113.50 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · May 03, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.